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Article: The Montreal definition and classification of gastroesophageal reflux disease: A global, evidence-based consensus paper | Die Montreal-definition und -klassifikation der gastroösophagealen refluxkrankheit: Ein globales evidenzbasiertes konsensus-papier

TitleThe Montreal definition and classification of gastroesophageal reflux disease: A global, evidence-based consensus paper | Die Montreal-definition und -klassifikation der gastroösophagealen refluxkrankheit: Ein globales evidenzbasiertes konsensus-papier
Authors
Issue Date2007
Citation
Zeitschrift Fur Gastroenterologie, 2007, v. 45 n. 11, p. 1125-1140 How to Cite?
AbstractAim: A world-wide recognised and accepted definition and classification of gastroesophageal reflux disease (GERD) would be highly desirable for research and clinical practice. The purpose of this project was to develop such a generally accepted definition and classification that could be used equally by patients, physicians, and supervisory bodies. Methods: In order to ensure a consensus among the participating experts a modifieddelphi process with a step-wise selection modality was employed. For this the working group of five persons formulated a series of statements on the basis of a systematic search of the literature using three databases (Embase, Cochrane-Study register, Medline). Then these statements were developed further for two years, revised and finally passed as consensus. The consensus group consisted of 44 experts from 18 countries. Each key vote was held on the basis of a six-point scale. A "consensus" was considered to have been reached when two-thirds of the participants voted in favour of the respective statement. Results: The level of agreement between the experts increased in the course of the multistep decision process, in the individual voting steps requiring at least two-thirds of the participants, the results were at first 86%, then 88% through to 94% and finally 100% in favour of the chosen statement. In the final voting, 94% of the final 51 statements were accepted by 90% of the consensus group. 90% of all statements were accepted unanimously or with only minor reservations. GERD was defined as a disease that is associated with troublesome symptoms and/or complications on account of reflux of stomach contents into the esophagus. The complaints are divided into esophageal and extra-esophageal syndromes. Among the novel aspects of this definition are the patient-orientated approach that is independent of endoscopic findings, the classification of the ailment into independent syndromes as well as the consideration of laryngitis, cough, asthma and dental problems as possible GERD syndromes. Furthermore, a new definition of suspected or demonstrated Barrett's esophagus is proposed. Conclusion: Irrespective of country-specific differences in terminology, language, prevalence and manifestations of this disease, evidence-based, world-wide valid consensus definitions are possible. A global consensus definition of GERD will simplify disease management, make mutual research possible and help in the design of generally valid studies. This will not only help the patient but also the physician and supervisory bodies. © Georg Thieme Verlag KG Stuttgart.
Persistent Identifierhttp://hdl.handle.net/10722/163135
ISSN
2015 Impact Factor: 1.357
2015 SCImago Journal Rankings: 0.293
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorVan Zanten, SVen_US
dc.contributor.authorKahrilas, Pen_US
dc.contributor.authorDent, Jen_US
dc.contributor.authorJones, Ren_US
dc.contributor.authorVakil, Nen_US
dc.contributor.authorAgreus, Len_US
dc.contributor.authorArmstrong, Den_US
dc.contributor.authorAttwood, Sen_US
dc.contributor.authorBergman, JFen_US
dc.contributor.authorBigard, MAen_US
dc.contributor.authorBlount, Pen_US
dc.contributor.authorBytzer, Pen_US
dc.contributor.authorChiba, Ten_US
dc.contributor.authorDelle Fave, Gen_US
dc.contributor.authorElSerag, Hen_US
dc.contributor.authorFan, Den_US
dc.contributor.authorFass, Ren_US
dc.contributor.authorFlook, Nen_US
dc.contributor.authorGalmiche, JPen_US
dc.contributor.authorHongo, Men_US
dc.contributor.authorIga, FHen_US
dc.contributor.authorJankowski, Jen_US
dc.contributor.authorJohnson, Den_US
dc.contributor.authorJohnssorn, Fen_US
dc.contributor.authorKatelaris, Pen_US
dc.contributor.authorKinoshita, Yen_US
dc.contributor.authorKlinkenbergKnol, Een_US
dc.contributor.authorLabenz, Jen_US
dc.contributor.authorLiker, Hen_US
dc.contributor.authorMalfertheiner, Pen_US
dc.contributor.authorMiwa, Hen_US
dc.contributor.authorMoayyedi, Pen_US
dc.contributor.authorPace, Fen_US
dc.contributor.authorPrado, Jen_US
dc.contributor.authorRichter, Jen_US
dc.contributor.authorSalis, Gen_US
dc.contributor.authorSanRen, Len_US
dc.contributor.authorSharma, Pen_US
dc.contributor.authorStanghellini, Ven_US
dc.contributor.authorTack, Jen_US
dc.contributor.authorTalley, Nen_US
dc.contributor.authorWong, Ben_US
dc.contributor.authorYaozong, Yen_US
dc.contributor.authorZapata, Cen_US
dc.date.accessioned2012-09-05T05:28:02Z-
dc.date.available2012-09-05T05:28:02Z-
dc.date.issued2007en_US
dc.identifier.citationZeitschrift Fur Gastroenterologie, 2007, v. 45 n. 11, p. 1125-1140en_US
dc.identifier.issn0044-2771en_US
dc.identifier.urihttp://hdl.handle.net/10722/163135-
dc.description.abstractAim: A world-wide recognised and accepted definition and classification of gastroesophageal reflux disease (GERD) would be highly desirable for research and clinical practice. The purpose of this project was to develop such a generally accepted definition and classification that could be used equally by patients, physicians, and supervisory bodies. Methods: In order to ensure a consensus among the participating experts a modifieddelphi process with a step-wise selection modality was employed. For this the working group of five persons formulated a series of statements on the basis of a systematic search of the literature using three databases (Embase, Cochrane-Study register, Medline). Then these statements were developed further for two years, revised and finally passed as consensus. The consensus group consisted of 44 experts from 18 countries. Each key vote was held on the basis of a six-point scale. A "consensus" was considered to have been reached when two-thirds of the participants voted in favour of the respective statement. Results: The level of agreement between the experts increased in the course of the multistep decision process, in the individual voting steps requiring at least two-thirds of the participants, the results were at first 86%, then 88% through to 94% and finally 100% in favour of the chosen statement. In the final voting, 94% of the final 51 statements were accepted by 90% of the consensus group. 90% of all statements were accepted unanimously or with only minor reservations. GERD was defined as a disease that is associated with troublesome symptoms and/or complications on account of reflux of stomach contents into the esophagus. The complaints are divided into esophageal and extra-esophageal syndromes. Among the novel aspects of this definition are the patient-orientated approach that is independent of endoscopic findings, the classification of the ailment into independent syndromes as well as the consideration of laryngitis, cough, asthma and dental problems as possible GERD syndromes. Furthermore, a new definition of suspected or demonstrated Barrett's esophagus is proposed. Conclusion: Irrespective of country-specific differences in terminology, language, prevalence and manifestations of this disease, evidence-based, world-wide valid consensus definitions are possible. A global consensus definition of GERD will simplify disease management, make mutual research possible and help in the design of generally valid studies. This will not only help the patient but also the physician and supervisory bodies. © Georg Thieme Verlag KG Stuttgart.en_US
dc.languageengen_US
dc.relation.ispartofZeitschrift fur Gastroenterologieen_US
dc.subject.meshEvidence-Based Medicineen_US
dc.subject.meshGastroesophageal Reflux - Classificationen_US
dc.subject.meshHumansen_US
dc.subject.meshInternationalityen_US
dc.subject.meshTerminology As Topicen_US
dc.titleThe Montreal definition and classification of gastroesophageal reflux disease: A global, evidence-based consensus paper | Die Montreal-definition und -klassifikation der gastroösophagealen refluxkrankheit: Ein globales evidenzbasiertes konsensus-papieren_US
dc.typeArticleen_US
dc.identifier.emailWong, B:bcywong@hku.hken_US
dc.identifier.authorityWong, B=rp00429en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1055/s-2007-963633en_US
dc.identifier.pmid18027314-
dc.identifier.scopuseid_2-s2.0-37349014577en_US
dc.identifier.volume45en_US
dc.identifier.issue11en_US
dc.identifier.spage1125en_US
dc.identifier.epage1140en_US
dc.identifier.isiWOS:000251508800010-
dc.identifier.scopusauthoridVan Zanten, SV=7004334673en_US
dc.identifier.scopusauthoridKahrilas, P=7102556261en_US
dc.identifier.scopusauthoridDent, J=7201577635en_US
dc.identifier.scopusauthoridJones, R=26643497700en_US
dc.identifier.scopusauthoridVakil, N=7102106058en_US
dc.identifier.scopusauthoridAgreus, L=7003997926en_US
dc.identifier.scopusauthoridArmstrong, D=7404406900en_US
dc.identifier.scopusauthoridAttwood, S=7005308203en_US
dc.identifier.scopusauthoridBergman, JF=23093318200en_US
dc.identifier.scopusauthoridBigard, MA=25932625900en_US
dc.identifier.scopusauthoridBlount, P=7007040478en_US
dc.identifier.scopusauthoridBytzer, P=7005590050en_US
dc.identifier.scopusauthoridChiba, T=7402420635en_US
dc.identifier.scopusauthoridDelle Fave, G=7007130920en_US
dc.identifier.scopusauthoridElSerag, H=7004977487en_US
dc.identifier.scopusauthoridFan, D=23093504500en_US
dc.identifier.scopusauthoridFass, R=7103304557en_US
dc.identifier.scopusauthoridFlook, N=6602160798en_US
dc.identifier.scopusauthoridGalmiche, JP=7102352811en_US
dc.identifier.scopusauthoridHongo, M=35901025600en_US
dc.identifier.scopusauthoridIga, FH=23094248900en_US
dc.identifier.scopusauthoridJankowski, J=7102760717en_US
dc.identifier.scopusauthoridJohnson, D=7406825008en_US
dc.identifier.scopusauthoridJohnssorn, F=23094255100en_US
dc.identifier.scopusauthoridKatelaris, P=7005727567en_US
dc.identifier.scopusauthoridKinoshita, Y=23093977000en_US
dc.identifier.scopusauthoridKlinkenbergKnol, E=35501869200en_US
dc.identifier.scopusauthoridLabenz, J=7007036791en_US
dc.identifier.scopusauthoridLiker, H=6506053015en_US
dc.identifier.scopusauthoridMalfertheiner, P=36048150200en_US
dc.identifier.scopusauthoridMiwa, H=7202031791en_US
dc.identifier.scopusauthoridMoayyedi, P=7005697363en_US
dc.identifier.scopusauthoridPace, F=7006204553en_US
dc.identifier.scopusauthoridPrado, J=7102168817en_US
dc.identifier.scopusauthoridRichter, J=7402925559en_US
dc.identifier.scopusauthoridSalis, G=7004468927en_US
dc.identifier.scopusauthoridSanRen, L=23095749200en_US
dc.identifier.scopusauthoridSharma, P=7403231562en_US
dc.identifier.scopusauthoridStanghellini, V=7006377452en_US
dc.identifier.scopusauthoridTack, J=7102745366en_US
dc.identifier.scopusauthoridTalley, N=36045241200en_US
dc.identifier.scopusauthoridWong, B=7402023340en_US
dc.identifier.scopusauthoridYaozong, Y=31767821500en_US
dc.identifier.scopusauthoridZapata, C=23096690800en_US

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