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Article: Prevalence and impact of vitamin D insufficiency in Southern Chinese adults

TitlePrevalence and impact of vitamin D insufficiency in Southern Chinese adults
Authors
Issue Date2007
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/ANM
Citation
Annals Of Nutrition And Metabolism, 2007, v. 51 n. 1, p. 59-64 How to Cite?
AbstractIntroduction: Vitamin D is a vital element for bone health but the problem of vitamin D deficiency is underestimated in Hong Kong. Methods: Serum 25(OH)D and parathyroid hormone (PTH) levels were evaluated in 382 community dwelling Chinese adults >50 years for their relation with bone mineral density (BMD) and risks of osteoporotic fractures and falls. Results: The mean age of the subjects was 69 ± 9 years. The mean 25(OH)D level was 28.3 ± 10.8 ng/ml with 62.8% of the subjects having levels <30 ng/ml. 6.3% of the subjects had elevated PTH levels. A curvilinear relation between serum PTH and 25(OH)D was found, with PTH starting to increase when 25(OH)D level fell below 30 ng/ml (r = -0.233, p < 0.05). Although subjects with vitamin D <30 ng/ml had significantly lower BMD, only sex, age and PTH but not 25(OH)D were predictors of BMD at the spine and hip. Subjects with elevated PTH levels had a 2.92-fold increased risk of falls and 2.94-fold increased risk of fractures at the hip and spine. Conclusions: Vitamin D insufficiency and its complication of secondary hyperparathyroidism is common even in subtropical region and is an important risk factor for low bone mass, falls and fractures. Copyright © 2007 S. Karger AG.
Persistent Identifierhttp://hdl.handle.net/10722/163072
ISSN
2015 Impact Factor: 2.461
2015 SCImago Journal Rankings: 1.062
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWat, WZMen_US
dc.contributor.authorLeung, JYYen_US
dc.contributor.authorTam, Sen_US
dc.contributor.authorKung, AWCen_US
dc.date.accessioned2012-09-05T05:27:14Z-
dc.date.available2012-09-05T05:27:14Z-
dc.date.issued2007en_US
dc.identifier.citationAnnals Of Nutrition And Metabolism, 2007, v. 51 n. 1, p. 59-64en_US
dc.identifier.issn0250-6807en_US
dc.identifier.urihttp://hdl.handle.net/10722/163072-
dc.description.abstractIntroduction: Vitamin D is a vital element for bone health but the problem of vitamin D deficiency is underestimated in Hong Kong. Methods: Serum 25(OH)D and parathyroid hormone (PTH) levels were evaluated in 382 community dwelling Chinese adults >50 years for their relation with bone mineral density (BMD) and risks of osteoporotic fractures and falls. Results: The mean age of the subjects was 69 ± 9 years. The mean 25(OH)D level was 28.3 ± 10.8 ng/ml with 62.8% of the subjects having levels <30 ng/ml. 6.3% of the subjects had elevated PTH levels. A curvilinear relation between serum PTH and 25(OH)D was found, with PTH starting to increase when 25(OH)D level fell below 30 ng/ml (r = -0.233, p < 0.05). Although subjects with vitamin D <30 ng/ml had significantly lower BMD, only sex, age and PTH but not 25(OH)D were predictors of BMD at the spine and hip. Subjects with elevated PTH levels had a 2.92-fold increased risk of falls and 2.94-fold increased risk of fractures at the hip and spine. Conclusions: Vitamin D insufficiency and its complication of secondary hyperparathyroidism is common even in subtropical region and is an important risk factor for low bone mass, falls and fractures. Copyright © 2007 S. Karger AG.en_US
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/ANMen_US
dc.relation.ispartofAnnals of Nutrition and Metabolismen_US
dc.subject.meshAgeden_US
dc.subject.meshBone Densityen_US
dc.subject.meshChinaen_US
dc.subject.meshFemaleen_US
dc.subject.meshFractures, Bone - Etiology - Physiopathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperparathyroidism, Secondaryen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOsteoporosis - Complications - Physiopathologyen_US
dc.subject.meshParathyroid Hormone - Blooden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshSterols - Blooden_US
dc.subject.meshVitamin D Deficiency - Blood - Epidemiologyen_US
dc.titlePrevalence and impact of vitamin D insufficiency in Southern Chinese adultsen_US
dc.typeArticleen_US
dc.identifier.emailKung, AWC:awckung@hku.hken_US
dc.identifier.authorityKung, AWC=rp00368en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1159/000100822en_US
dc.identifier.pmid17356256-
dc.identifier.scopuseid_2-s2.0-34247359958en_US
dc.identifier.hkuros131080-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34247359958&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume51en_US
dc.identifier.issue1en_US
dc.identifier.spage59en_US
dc.identifier.epage64en_US
dc.identifier.isiWOS:000246173700009-
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridWat, WZM=16240409500en_US
dc.identifier.scopusauthoridLeung, JYY=36340060100en_US
dc.identifier.scopusauthoridTam, S=7202037323en_US
dc.identifier.scopusauthoridKung, AWC=7102322339en_US

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