Article: Innate immunity and systemic lupus erythematosus

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleInnate immunity and systemic lupus erythematosus
AuthorsJin, O2
Sun, L1
Kavikondala, S2
Lau, CS2
KeywordsDisease Aetiology And Pathogenesis
Innate Immunity
Lymphocyte Activation
Systemic Lupus Erythematous
Issue Date2006
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APL
CitationAplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 359-364 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1479-8077.2006.00229.x
AbstractInnate immunity is the first-line host defence against pathogens and damaged host cells, and the major cellular components are phagocytes such as monocytes/macrophages, polymorphonuclear cells and dendritic cells. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of tolerance to self-antigens, the source of which has been suggested to be apoptotic cells. In this article, we will review studies on apoptosis in SLE and discuss the contribution of innate immunity abnormalities in the development of this condition. © 2006 Asia Pacific League of Associations for Rheumatology.
ISSN0219-0494
DOIhttp://dx.doi.org/10.1111/j.1479-8077.2006.00229.x
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorJin, O
dc.contributor.authorSun, L
dc.contributor.authorKavikondala, S
dc.contributor.authorLau, CS
dc.date.accessioned2012-09-05T05:26:54Z
dc.date.available2012-09-05T05:26:54Z
dc.date.issued2006
dc.description.abstractInnate immunity is the first-line host defence against pathogens and damaged host cells, and the major cellular components are phagocytes such as monocytes/macrophages, polymorphonuclear cells and dendritic cells. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the loss of tolerance to self-antigens, the source of which has been suggested to be apoptotic cells. In this article, we will review studies on apoptosis in SLE and discuss the contribution of innate immunity abnormalities in the development of this condition. © 2006 Asia Pacific League of Associations for Rheumatology.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationAplar Journal Of Rheumatology, 2006, v. 9 n. 4, p. 359-364 [How to Cite?]
DOI: http://dx.doi.org/10.1111/j.1479-8077.2006.00229.x
dc.identifier.doihttp://dx.doi.org/10.1111/j.1479-8077.2006.00229.x
dc.identifier.epage364
dc.identifier.issn0219-0494
dc.identifier.issue4
dc.identifier.scopuseid_2-s2.0-33750991860
dc.identifier.spage359
dc.identifier.urihttp://hdl.handle.net/10722/163044
dc.identifier.volume9
dc.languageeng
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APL
dc.publisher.placeAustralia
dc.relation.ispartofAPLAR Journal of Rheumatology
dc.relation.referencesReferences in Scopus
dc.subjectDisease Aetiology And Pathogenesis
dc.subjectInnate Immunity
dc.subjectLymphocyte Activation
dc.subjectSystemic Lupus Erythematous
dc.titleInnate immunity and systemic lupus erythematosus
dc.typeArticle
Author Affiliations
  1. Nanjing University
  2. The University of Hong Kong