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Article: Updated spirometric reference values for adult Chinese in Hong Kong and implications on clinical utilization

TitleUpdated spirometric reference values for adult Chinese in Hong Kong and implications on clinical utilization
Authors
Issue Date2006
PublisherAmerican College of Chest Physicians. The Journal's web site is located at http://www.chestjournal.org
Citation
Chest, 2006, v. 129 n. 2, p. 384-392 How to Cite?
AbstractStudy objectives: The accuracy of reference values of lung function is important for assessment of severity and functional impairment of respiratory diseases. The aim of the study was to establish updated prediction formulae of spirometric parameters for Hong Kong Chinese and to compare the reference values with those derived from other studies in white and Chinese subjects. Design: Cross-sectional multicenter study. Setting: Lung function laboratories of eight regional hospitals in Hong Kong. Participants: Subjects were recruited by random-digit dialing. One thousand one hundred seventy-six subjects who fulfilled recruitment criteria underwent spirometry. Measurements: Spirometry was performed according to American Thoracic Society recommendations, and the technique was standardized among the eight participating lung function laboratories. Results: Evaluable data of 1,089 (494 men and 595 women) healthy nonsmokers aged 18 to 80 years were analyzed. Age and height were found to be the major determinants of FEV 1 and FVC, with a linear decline of height-adjusted values with age in both sexes. Spirometric values of this population have increased compared to Chinese populations of similar sex, age, and height two decades ago. Reference values derived from white populations were higher than our values by 5 to 19%, and the degree of overestimation varied with age, sex, and lung function parameter. We also demonstrated that the blanket application of correction factors for Asian populations may not be appropriate. In this study cohort, the distribution-free estimation of age-related centiles was more appropriate for the determination of lower limits of normal. Conclusions: Our findings underscore the need to use reference values based on updated data derived from local populations or those matched for ethnicity and other sociodemographic characteristics.
Persistent Identifierhttp://hdl.handle.net/10722/162941
ISSN
2015 Impact Factor: 5.94
2015 SCImago Journal Rankings: 3.176
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorIp, MSMen_US
dc.contributor.authorKo, FWSen_US
dc.contributor.authorLau, ACWen_US
dc.contributor.authorYu, WCen_US
dc.contributor.authorTang, KSen_US
dc.contributor.authorChoo, Ken_US
dc.contributor.authorChan-Yeung, MMWen_US
dc.date.accessioned2012-09-05T05:25:37Z-
dc.date.available2012-09-05T05:25:37Z-
dc.date.issued2006en_US
dc.identifier.citationChest, 2006, v. 129 n. 2, p. 384-392en_US
dc.identifier.issn0012-3692en_US
dc.identifier.urihttp://hdl.handle.net/10722/162941-
dc.description.abstractStudy objectives: The accuracy of reference values of lung function is important for assessment of severity and functional impairment of respiratory diseases. The aim of the study was to establish updated prediction formulae of spirometric parameters for Hong Kong Chinese and to compare the reference values with those derived from other studies in white and Chinese subjects. Design: Cross-sectional multicenter study. Setting: Lung function laboratories of eight regional hospitals in Hong Kong. Participants: Subjects were recruited by random-digit dialing. One thousand one hundred seventy-six subjects who fulfilled recruitment criteria underwent spirometry. Measurements: Spirometry was performed according to American Thoracic Society recommendations, and the technique was standardized among the eight participating lung function laboratories. Results: Evaluable data of 1,089 (494 men and 595 women) healthy nonsmokers aged 18 to 80 years were analyzed. Age and height were found to be the major determinants of FEV 1 and FVC, with a linear decline of height-adjusted values with age in both sexes. Spirometric values of this population have increased compared to Chinese populations of similar sex, age, and height two decades ago. Reference values derived from white populations were higher than our values by 5 to 19%, and the degree of overestimation varied with age, sex, and lung function parameter. We also demonstrated that the blanket application of correction factors for Asian populations may not be appropriate. In this study cohort, the distribution-free estimation of age-related centiles was more appropriate for the determination of lower limits of normal. Conclusions: Our findings underscore the need to use reference values based on updated data derived from local populations or those matched for ethnicity and other sociodemographic characteristics.en_US
dc.languageengen_US
dc.publisherAmerican College of Chest Physicians. The Journal's web site is located at http://www.chestjournal.orgen_US
dc.relation.ispartofChesten_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshFemaleen_US
dc.subject.meshForced Expiratory Volumeen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshReference Valuesen_US
dc.subject.meshSpirometryen_US
dc.subject.meshVital Capacityen_US
dc.titleUpdated spirometric reference values for adult Chinese in Hong Kong and implications on clinical utilizationen_US
dc.typeArticleen_US
dc.identifier.emailIp, MSM:msmip@hku.hken_US
dc.identifier.authorityIp, MSM=rp00347en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1378/chest.129.2.384en_US
dc.identifier.pmid16478856-
dc.identifier.scopuseid_2-s2.0-33344468696en_US
dc.identifier.hkuros118991-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33344468696&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume129en_US
dc.identifier.issue2en_US
dc.identifier.spage384en_US
dc.identifier.epage392en_US
dc.identifier.isiWOS:000235646100027-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridIp, MSM=7102423259en_US
dc.identifier.scopusauthoridKo, FWS=7103224911en_US
dc.identifier.scopusauthoridLau, ACW=7202626205en_US
dc.identifier.scopusauthoridYu, WC=7403914214en_US
dc.identifier.scopusauthoridTang, KS=15065968800en_US
dc.identifier.scopusauthoridChoo, K=23391819100en_US
dc.identifier.scopusauthoridChan-Yeung, MMW=54790582200en_US

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