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Article: Eosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)

TitleEosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)
Authors
Issue Date2005
PublisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lal
Citation
Leukemia And Lymphoma, 2005, v. 46 n. 3, p. 447-450 How to Cite?
AbstractWe report a rare case of eosinophilic leukemia transformation in a patient with polycythemia rubra vera on hydroxycarbamide (hydroxyurea) therapy only. Cytogenetic study showed complex abnormalities including -5, -7, +8, suggestive of a secondary leukemia. The leukemogenic risk of hydroxycarbamide, a ribonucleoside reductase, and the risk of natural leukemic transformation of polycythemia rubra vera is discussed in the context of previous PVSG studies. © 2005 Taylor & Francis Group Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/162788
ISSN
2015 Impact Factor: 3.093
2015 SCImago Journal Rankings: 1.202
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChim, CSen_US
dc.contributor.authorMa, SKen_US
dc.date.accessioned2012-09-05T05:23:32Z-
dc.date.available2012-09-05T05:23:32Z-
dc.date.issued2005en_US
dc.identifier.citationLeukemia And Lymphoma, 2005, v. 46 n. 3, p. 447-450en_US
dc.identifier.issn1042-8194en_US
dc.identifier.urihttp://hdl.handle.net/10722/162788-
dc.description.abstractWe report a rare case of eosinophilic leukemia transformation in a patient with polycythemia rubra vera on hydroxycarbamide (hydroxyurea) therapy only. Cytogenetic study showed complex abnormalities including -5, -7, +8, suggestive of a secondary leukemia. The leukemogenic risk of hydroxycarbamide, a ribonucleoside reductase, and the risk of natural leukemic transformation of polycythemia rubra vera is discussed in the context of previous PVSG studies. © 2005 Taylor & Francis Group Ltd.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://informahealthcare.com/loi/lalen_US
dc.relation.ispartofLeukemia and Lymphomaen_US
dc.rightsLeukemia and Lymphoma. Copyright © Informa Healthcare.-
dc.subject.meshAgeden_US
dc.subject.meshChromosome Aberrationsen_US
dc.subject.meshCytogenetic Analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshHydroxyurea - Therapeutic Useen_US
dc.subject.meshHypereosinophilic Syndrome - Complications - Drug Therapy - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshPolycythemia Vera - Complications - Drug Therapyen_US
dc.titleEosinophilic leukemic transformation in Polycythemia Rubra Vera (PRV)en_US
dc.typeArticleen_US
dc.identifier.emailChim, CS:jcschim@hku.hken_US
dc.identifier.authorityChim, CS=rp00408en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1080/10428190400007649en_US
dc.identifier.pmid15621837en_US
dc.identifier.scopuseid_2-s2.0-13544272027en_US
dc.identifier.hkuros99021-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-13544272027&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume46en_US
dc.identifier.issue3en_US
dc.identifier.spage447en_US
dc.identifier.epage450en_US
dc.identifier.isiWOS:000225878000018-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChim, CS=7004597253en_US
dc.identifier.scopusauthoridMa, SK=37020910400en_US

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