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Article: Long-term prospective follow-up of endoscopic oesophagitis in southern Chinese - Prevalence and spectrum of the disease

TitleLong-term prospective follow-up of endoscopic oesophagitis in southern Chinese - Prevalence and spectrum of the disease
Authors
Issue Date2002
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APT
Citation
Alimentary Pharmacology And Therapeutics, 2002, v. 16 n. 12, p. 2037-2042 How to Cite?
AbstractAims: To study the prevalence, clinical characteristics and long-term outcome of oesophagitis in Chinese patients. Methods: Clinical and endoscopic data were collected prospectively from consecutive patients who underwent upper endoscopy between 1997 and 2001. Patients with endoscopic oesophagitis were graded according to the Los Angeles system and analysed according to their clinical presentation, endoscopic details, Helicobacter pylori status, non-steroidal anti-inflammatory drug history, co-morbidity and mortality. Results: A total of 22 628 upper endoscopies were performed in 16 606 patients. Of these, 631 (3.8%) had endoscopic oesophagitis, 14 had benign oesophageal stricture (0.08%) and 10 had Barrett's oesophagus (0.06%). Most patients (94%) had either Los Angeles grade A or grade B oesophagitis. Patients who died during follow-up had a significantly higher incidence of co-morbid illness (100% vs. 63%, P < 0.001). By Cox regression analysis, the presence of gastrointestinal bleeding (P = 0.008), advanced age (P = 0.004) and the use of Ryle's tube (P = 0.043) were identified to be independent factors associated with mortality. Conclusions: Complicated gastro-oesophageal reflux disease is uncommon in the Asian population. Advanced age, use of Ryle's tube and the presence of gastrointestinal bleeding are associated with a poor long-term outcome, which is a reflection of the severe underlying co-morbidity.
Persistent Identifierhttp://hdl.handle.net/10722/162644
ISSN
2015 Impact Factor: 6.32
2015 SCImago Journal Rankings: 2.833
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_US
dc.contributor.authorLam, SKen_US
dc.contributor.authorHui, WMen_US
dc.contributor.authorLai, KCen_US
dc.contributor.authorChan, CKen_US
dc.contributor.authorHu, WHCen_US
dc.contributor.authorXia, HHXen_US
dc.contributor.authorHui, CKen_US
dc.contributor.authorYuen, MFen_US
dc.contributor.authorChan, AOOen_US
dc.contributor.authorWong, BCYen_US
dc.date.accessioned2012-09-05T05:22:01Z-
dc.date.available2012-09-05T05:22:01Z-
dc.date.issued2002en_US
dc.identifier.citationAlimentary Pharmacology And Therapeutics, 2002, v. 16 n. 12, p. 2037-2042en_US
dc.identifier.issn0269-2813en_US
dc.identifier.urihttp://hdl.handle.net/10722/162644-
dc.description.abstractAims: To study the prevalence, clinical characteristics and long-term outcome of oesophagitis in Chinese patients. Methods: Clinical and endoscopic data were collected prospectively from consecutive patients who underwent upper endoscopy between 1997 and 2001. Patients with endoscopic oesophagitis were graded according to the Los Angeles system and analysed according to their clinical presentation, endoscopic details, Helicobacter pylori status, non-steroidal anti-inflammatory drug history, co-morbidity and mortality. Results: A total of 22 628 upper endoscopies were performed in 16 606 patients. Of these, 631 (3.8%) had endoscopic oesophagitis, 14 had benign oesophageal stricture (0.08%) and 10 had Barrett's oesophagus (0.06%). Most patients (94%) had either Los Angeles grade A or grade B oesophagitis. Patients who died during follow-up had a significantly higher incidence of co-morbid illness (100% vs. 63%, P < 0.001). By Cox regression analysis, the presence of gastrointestinal bleeding (P = 0.008), advanced age (P = 0.004) and the use of Ryle's tube (P = 0.043) were identified to be independent factors associated with mortality. Conclusions: Complicated gastro-oesophageal reflux disease is uncommon in the Asian population. Advanced age, use of Ryle's tube and the presence of gastrointestinal bleeding are associated with a poor long-term outcome, which is a reflection of the severe underlying co-morbidity.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/APTen_US
dc.relation.ispartofAlimentary Pharmacology and Therapeuticsen_US
dc.rightsAlimentary Pharmacology and Therapeutics. Copyright © Blackwell Publishing Ltd.-
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshBarrett Esophagus - Epidemiologyen_US
dc.subject.meshCause Of Deathen_US
dc.subject.meshComorbidityen_US
dc.subject.meshEsophageal Stenosis - Epidemiologyen_US
dc.subject.meshEsophagitis - Epidemiology - Microbiologyen_US
dc.subject.meshEsophagoscopyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHelicobacter Infections - Complicationsen_US
dc.subject.meshHelicobacter Pylori - Isolation & Purificationen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSeverity Of Illness Indexen_US
dc.titleLong-term prospective follow-up of endoscopic oesophagitis in southern Chinese - Prevalence and spectrum of the diseaseen_US
dc.typeArticleen_US
dc.identifier.emailYuen, MF:mfyuen@hkucc.hku.hken_US
dc.identifier.emailWong, BCY:bcywong@hku.hken_US
dc.identifier.authorityYuen, MF=rp00479en_US
dc.identifier.authorityWong, BCY=rp00429en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1046/j.1365-2036.2002.01373.xen_US
dc.identifier.pmid12452935-
dc.identifier.scopuseid_2-s2.0-0036913944en_US
dc.identifier.hkuros80520-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036913944&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume16en_US
dc.identifier.issue12en_US
dc.identifier.spage2037en_US
dc.identifier.epage2042en_US
dc.identifier.isiWOS:000179529900006-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridWong, WM=36847934700en_US
dc.identifier.scopusauthoridLam, SK=7402279473en_US
dc.identifier.scopusauthoridHui, WM=7103196477en_US
dc.identifier.scopusauthoridLai, KC=7402135595en_US
dc.identifier.scopusauthoridChan, CK=7404813960en_US
dc.identifier.scopusauthoridHu, WHC=25932937100en_US
dc.identifier.scopusauthoridXia, HHX=8757161400en_US
dc.identifier.scopusauthoridHui, CK=14054127700en_US
dc.identifier.scopusauthoridYuen, MF=7102031955en_US
dc.identifier.scopusauthoridChan, AOO=7403167965en_US
dc.identifier.scopusauthoridWong, BCY=7402023340en_US

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