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Article: Accuracy of a new near patient test for the diagnosis of Helicobacter pylori infection in Chinese

TitleAccuracy of a new near patient test for the diagnosis of Helicobacter pylori infection in Chinese
Authors
Issue Date2002
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
Journal Of Gastroenterology And Hepatology, 2002, v. 17 n. 12, p. 1272-1277 How to Cite?
AbstractBackground and Aim: The performance of existing near patient tests for the diagnosis ofHelicobacter pylori remains unsatisfactory. The aim of this study is to evaluate the accuracy of a new near patient test (Signify H. pylori) for the diagnosis of H. pylori and the usefulness of the Signify H. pylori test for a test and treat strategy. Methods: Consecutive dyspeptic patients referred for upper endoscopy were recruited. Rapid urease test and histology were used as the gold standard. After endoscopy, blood was collected for the Signify H. pylori test and compared with a gold standard. Results: Two hundred and forty-four patients were eligible for analysis and 121 (49.5%) were positive for H. pylori. The Signify H. pylori test showed a sensitivity, specificity, and accuracy of 84.3, 89.4%, and 86.9%, respectively, for whole blood and 79.3, 88.6, and 84.0% for serum, respectively. The sensitivity and specificity of the Signify H. pylori whole blood test was 87.5 and 92.6% for patients less than 45-years-old and the accuracy was similar between patients referred from primary care physicians or gastroenterologists. The test is easy to operate and results are available within 5 min. Conclusion: The Signify H. pylori test is accurate for the near patient diagnosis of H. pylori infection. © 2002 Blackwell Publishing Asia Pty Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/162613
ISSN
2015 Impact Factor: 3.322
2015 SCImago Journal Rankings: 1.190
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, WMen_US
dc.contributor.authorLam, SKen_US
dc.contributor.authorXia, HHXen_US
dc.contributor.authorTang, VSYen_US
dc.contributor.authorLai, KCen_US
dc.contributor.authorHu, WHCen_US
dc.contributor.authorChan, CKen_US
dc.contributor.authorCheung, KLen_US
dc.contributor.authorWong, BCYen_US
dc.date.accessioned2012-09-05T05:21:40Z-
dc.date.available2012-09-05T05:21:40Z-
dc.date.issued2002en_US
dc.identifier.citationJournal Of Gastroenterology And Hepatology, 2002, v. 17 n. 12, p. 1272-1277en_US
dc.identifier.issn0815-9319en_US
dc.identifier.urihttp://hdl.handle.net/10722/162613-
dc.description.abstractBackground and Aim: The performance of existing near patient tests for the diagnosis ofHelicobacter pylori remains unsatisfactory. The aim of this study is to evaluate the accuracy of a new near patient test (Signify H. pylori) for the diagnosis of H. pylori and the usefulness of the Signify H. pylori test for a test and treat strategy. Methods: Consecutive dyspeptic patients referred for upper endoscopy were recruited. Rapid urease test and histology were used as the gold standard. After endoscopy, blood was collected for the Signify H. pylori test and compared with a gold standard. Results: Two hundred and forty-four patients were eligible for analysis and 121 (49.5%) were positive for H. pylori. The Signify H. pylori test showed a sensitivity, specificity, and accuracy of 84.3, 89.4%, and 86.9%, respectively, for whole blood and 79.3, 88.6, and 84.0% for serum, respectively. The sensitivity and specificity of the Signify H. pylori whole blood test was 87.5 and 92.6% for patients less than 45-years-old and the accuracy was similar between patients referred from primary care physicians or gastroenterologists. The test is easy to operate and results are available within 5 min. Conclusion: The Signify H. pylori test is accurate for the near patient diagnosis of H. pylori infection. © 2002 Blackwell Publishing Asia Pty Ltd.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGHen_US
dc.relation.ispartofJournal of Gastroenterology and Hepatologyen_US
dc.subject.meshAdulten_US
dc.subject.meshBiopsyen_US
dc.subject.meshChina - Epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGastric Mucosa - Microbiologyen_US
dc.subject.meshGastroscopyen_US
dc.subject.meshHelicobacter Infections - Diagnosis - Epidemiologyen_US
dc.subject.meshHelicobacter Pylorien_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshUrease - Metabolismen_US
dc.titleAccuracy of a new near patient test for the diagnosis of Helicobacter pylori infection in Chineseen_US
dc.typeArticleen_US
dc.identifier.emailWong, BCY:bcywong@hku.hken_US
dc.identifier.authorityWong, BCY=rp00429en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1046/j.1440-1746.2002.02879.xen_US
dc.identifier.pmid12423271-
dc.identifier.scopuseid_2-s2.0-0036433045en_US
dc.identifier.hkuros82281-
dc.identifier.hkuros80345-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036433045&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume17en_US
dc.identifier.issue12en_US
dc.identifier.spage1272en_US
dc.identifier.epage1277en_US
dc.identifier.isiWOS:000179111400006-
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridWong, WM=7403972413en_US
dc.identifier.scopusauthoridLam, SK=7402279473en_US
dc.identifier.scopusauthoridXia, HHX=8757161400en_US
dc.identifier.scopusauthoridTang, VSY=6701711948en_US
dc.identifier.scopusauthoridLai, KC=7402135595en_US
dc.identifier.scopusauthoridHu, WHC=25932937100en_US
dc.identifier.scopusauthoridChan, CK=7404813960en_US
dc.identifier.scopusauthoridCheung, KL=7402406543en_US
dc.identifier.scopusauthoridWong, BCY=7402023340en_US

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