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Article: Atrial fibrillation induction and determination of atrial vulnerable period using very low energy synchronized biatrial shock in normal subjects and in patients with atrial fibrillation

TitleAtrial fibrillation induction and determination of atrial vulnerable period using very low energy synchronized biatrial shock in normal subjects and in patients with atrial fibrillation
Authors
Issue Date2000
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1
Citation
Pace - Pacing And Clinical Electrophysiology, 2000, v. 23 n. 4 pt. 1, p. 469-476 How to Cite?
AbstractThe atrial vulnerable periods (AVP) for shock induction of atrial fibrillation (AF) in humans have not been clearly defined. Furthermore, the safety and efficacy of using low energy biatrial shock delivered transvenously for AF induction are unknown. We tested the safety and efficacy of using very low energy biatrial shocks, delivered between the right atrium and the coronary sinus for AF induction and used this technique to characterize the AVP in nine controls and nine patients with AF. Thirty-volt and 60-V 3/3-ms biphasic shocks were delivered, starting from 50 ms before the atrial effective refractory period with 20-ms increments until the end of the QRS interval to determine the AVP front, AVP end, and the AVP duration. Successful AF induction could be achieved in eight (89%) of the nine controls and in nine (100%) of the nine patients with AF without any complication. In patients with AF, the A VP front started significantly earlier within the QRS complex, and the AVP duration and the A VP duration/QRS percent ratios were also significantly greater as compared to controls. Furthermore, a higher induction shock energy in patients with AF was associated with an increase in AF inducibility and significantly increased the AVP duration and AVP duration/QRS percent ratio as compared to the controls. This study demonstrated the safe and efficacy of delivering a very low energy biatrial shock during the AVP within the R wave for AF induction. The characteristics of AVP in patients with AF were significantly different from normal subjects.
Persistent Identifierhttp://hdl.handle.net/10722/162426
ISSN
2015 Impact Factor: 1.156
2015 SCImago Journal Rankings: 0.662
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTse, HFen_US
dc.contributor.authorLau, CPen_US
dc.contributor.authorAyers, GMen_US
dc.date.accessioned2012-09-05T05:19:48Z-
dc.date.available2012-09-05T05:19:48Z-
dc.date.issued2000en_US
dc.identifier.citationPace - Pacing And Clinical Electrophysiology, 2000, v. 23 n. 4 pt. 1, p. 469-476en_US
dc.identifier.issn0147-8389en_US
dc.identifier.urihttp://hdl.handle.net/10722/162426-
dc.description.abstractThe atrial vulnerable periods (AVP) for shock induction of atrial fibrillation (AF) in humans have not been clearly defined. Furthermore, the safety and efficacy of using low energy biatrial shock delivered transvenously for AF induction are unknown. We tested the safety and efficacy of using very low energy biatrial shocks, delivered between the right atrium and the coronary sinus for AF induction and used this technique to characterize the AVP in nine controls and nine patients with AF. Thirty-volt and 60-V 3/3-ms biphasic shocks were delivered, starting from 50 ms before the atrial effective refractory period with 20-ms increments until the end of the QRS interval to determine the AVP front, AVP end, and the AVP duration. Successful AF induction could be achieved in eight (89%) of the nine controls and in nine (100%) of the nine patients with AF without any complication. In patients with AF, the A VP front started significantly earlier within the QRS complex, and the AVP duration and the A VP duration/QRS percent ratios were also significantly greater as compared to controls. Furthermore, a higher induction shock energy in patients with AF was associated with an increase in AF inducibility and significantly increased the AVP duration and AVP duration/QRS percent ratio as compared to the controls. This study demonstrated the safe and efficacy of delivering a very low energy biatrial shock during the AVP within the R wave for AF induction. The characteristics of AVP in patients with AF were significantly different from normal subjects.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0147-8389&site=1en_US
dc.relation.ispartofPACE - Pacing and Clinical Electrophysiologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAtrial Fibrillation - Physiopathology - Therapyen_US
dc.subject.meshCatheterization, Peripheralen_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshElectric Countershock - Methodsen_US
dc.subject.meshElectrocardiographyen_US
dc.subject.meshEquipment Safetyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFemoral Veinen_US
dc.subject.meshHeart Conduction System - Physiopathologyen_US
dc.subject.meshHeart Rate - Physiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSubclavian Veinen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleAtrial fibrillation induction and determination of atrial vulnerable period using very low energy synchronized biatrial shock in normal subjects and in patients with atrial fibrillationen_US
dc.typeArticleen_US
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_US
dc.identifier.authorityTse, HF=rp00428en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1540-8159.2000.tb00829.x-
dc.identifier.pmid10793436-
dc.identifier.scopuseid_2-s2.0-0034104263en_US
dc.identifier.hkuros54846-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034104263&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue4 pt. 1en_US
dc.identifier.spage469en_US
dc.identifier.epage476en_US
dc.identifier.isiWOS:000086541500011-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridTse, HF=7006070805en_US
dc.identifier.scopusauthoridLau, CP=7401968501en_US
dc.identifier.scopusauthoridAyers, GM=7102015157en_US

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