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Article: Antithyroid drug-induced agranulocytosis

TitleAntithyroid drug-induced agranulocytosis
Authors
KeywordsAgranulocytosis
Antithyroid Agents
Granulocyte Colony-Stimulating Factor
Issue Date1999
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
Citation
Hong Kong Medical Journal, 1999, v. 5 n. 4, p. 394-396 How to Cite?
AbstractThyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis. We report on two patients with antithyroid drug-induced agranulocytosis. Both patients presented with fever and severe neutropenia. The administration of granulocyte colony-stimulating factor resulted in a dramatic improvement in the white blood cell count and symptoms. Antithyroid drug-induced agranulocytosis is a potentially lethal condition but is completely reversible when recognised early and when prompt treatment is offered.
Persistent Identifierhttp://hdl.handle.net/10722/162359
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorLee, CHen_US
dc.contributor.authorLiang, RHSen_US
dc.date.accessioned2012-09-05T05:19:16Z-
dc.date.available2012-09-05T05:19:16Z-
dc.date.issued1999en_US
dc.identifier.citationHong Kong Medical Journal, 1999, v. 5 n. 4, p. 394-396en_US
dc.identifier.issn1024-2708en_US
dc.identifier.urihttp://hdl.handle.net/10722/162359-
dc.description.abstractThyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis. We report on two patients with antithyroid drug-induced agranulocytosis. Both patients presented with fever and severe neutropenia. The administration of granulocyte colony-stimulating factor resulted in a dramatic improvement in the white blood cell count and symptoms. Antithyroid drug-induced agranulocytosis is a potentially lethal condition but is completely reversible when recognised early and when prompt treatment is offered.en_US
dc.languageengen_US
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.htmlen_US
dc.relation.ispartofHong Kong Medical Journalen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectAgranulocytosisen_US
dc.subjectAntithyroid Agentsen_US
dc.subjectGranulocyte Colony-Stimulating Factoren_US
dc.titleAntithyroid drug-induced agranulocytosisen_US
dc.typeArticleen_US
dc.identifier.emailLiang, RHS:rliang@hku.hken_US
dc.identifier.authorityLiang, RHS=rp00345en_US
dc.description.naturepublished_or_final_versionen_US
dc.identifier.scopuseid_2-s2.0-0033374173en_US
dc.identifier.volume5en_US
dc.identifier.issue4en_US
dc.identifier.spage394en_US
dc.identifier.epage396en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridLee, CH=8087416700en_US
dc.identifier.scopusauthoridLiang, RHS=26643224900en_US

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