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Article: Tuberculous meningitis in Hong Kong: Experience in a regional hospital

TitleTuberculous meningitis in Hong Kong: Experience in a regional hospital
Authors
Issue Date1998
PublisherInternational Union against Tuberculosis and Lung Disease. The Journal's web site is located at http://www.theunion.org/about-the-journal/about-the-journal.html
Citation
International Journal Of Tuberculosis And Lung Disease, 1998, v. 2 n. 12, p. 1040-1043 How to Cite?
AbstractTuberculous meningitis (TBM) remains common in Hong Kong. From January 1996 to June 1997, 11 adult patients with TBM presented to Queen Mary Hospital, a regional hospital in Hong Kong. The annual incidence of TBM was estimated at 1.8 per 100 000 population. Nine patients were local Chinese, and only one patient had the acquired immune-deficiency syndrome (AIDS). In contrast to the classical presentation as a chronic indolent disease, our patients presented acutely: the mean duration from onset of symptoms to presentation was 4.8 days (range 0-10). The most common presenting symptoms were headache (64%), fever (46%), or both (36%), with focal deficits occurring in 64% of patients. Cerebrospinal fluid (CSF) culture and polymerase chain reaction (PCR) were positive in 30% and 29% of cases. Mean CSF cell count, protein and glucose levels were 340 x 106/L, 267 mg/dL, and 2.3 mmol/L, respectively. Extra-neural tuberculosis occurred in 46% of cases. All patients survived and responded to treatment. Drug-induced hepatotoxicity was common; 64% of patients developed biochemical hepatitis.
Persistent Identifierhttp://hdl.handle.net/10722/162256
ISSN
2015 Impact Factor: 2.148
2015 SCImago Journal Rankings: 1.381
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMak, Wen_US
dc.contributor.authorCheung, RTFen_US
dc.contributor.authorHo, SLen_US
dc.contributor.authorTsang, KLen_US
dc.contributor.authorFong, GCYen_US
dc.date.accessioned2012-09-05T05:18:26Z-
dc.date.available2012-09-05T05:18:26Z-
dc.date.issued1998en_US
dc.identifier.citationInternational Journal Of Tuberculosis And Lung Disease, 1998, v. 2 n. 12, p. 1040-1043en_US
dc.identifier.issn1027-3719en_US
dc.identifier.urihttp://hdl.handle.net/10722/162256-
dc.description.abstractTuberculous meningitis (TBM) remains common in Hong Kong. From January 1996 to June 1997, 11 adult patients with TBM presented to Queen Mary Hospital, a regional hospital in Hong Kong. The annual incidence of TBM was estimated at 1.8 per 100 000 population. Nine patients were local Chinese, and only one patient had the acquired immune-deficiency syndrome (AIDS). In contrast to the classical presentation as a chronic indolent disease, our patients presented acutely: the mean duration from onset of symptoms to presentation was 4.8 days (range 0-10). The most common presenting symptoms were headache (64%), fever (46%), or both (36%), with focal deficits occurring in 64% of patients. Cerebrospinal fluid (CSF) culture and polymerase chain reaction (PCR) were positive in 30% and 29% of cases. Mean CSF cell count, protein and glucose levels were 340 x 106/L, 267 mg/dL, and 2.3 mmol/L, respectively. Extra-neural tuberculosis occurred in 46% of cases. All patients survived and responded to treatment. Drug-induced hepatotoxicity was common; 64% of patients developed biochemical hepatitis.en_US
dc.languageengen_US
dc.publisherInternational Union against Tuberculosis and Lung Disease. The Journal's web site is located at http://www.theunion.org/about-the-journal/about-the-journal.htmlen_US
dc.relation.ispartofInternational Journal of Tuberculosis and Lung Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntitubercular Agents - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHospitals, Urbanen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTuberculosis, Meningeal - Diagnosis - Drug Therapy - Epidemiologyen_US
dc.titleTuberculous meningitis in Hong Kong: Experience in a regional hospitalen_US
dc.typeArticleen_US
dc.identifier.emailCheung, RTF:rtcheung@hku.hken_US
dc.identifier.emailHo, SL:slho@hku.hken_US
dc.identifier.authorityCheung, RTF=rp00434en_US
dc.identifier.authorityHo, SL=rp00240en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid9869123-
dc.identifier.scopuseid_2-s2.0-0032217305en_US
dc.identifier.hkuros42931-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032217305&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume2en_US
dc.identifier.issue12en_US
dc.identifier.spage1040en_US
dc.identifier.epage1043en_US
dc.identifier.isiWOS:000077449700015-
dc.publisher.placeFranceen_US
dc.identifier.scopusauthoridMak, W=22948344000en_US
dc.identifier.scopusauthoridCheung, RTF=7202397498en_US
dc.identifier.scopusauthoridHo, SL=25959633500en_US
dc.identifier.scopusauthoridTsang, KL=7201554745en_US
dc.identifier.scopusauthoridFong, GCY=7004978754en_US

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