File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Near tetraploidy in three cases of acute myeloid leukemia associated with mediastinal granulocytic sarcoma

TitleNear tetraploidy in three cases of acute myeloid leukemia associated with mediastinal granulocytic sarcoma
Authors
Issue Date1998
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 1998, v. 102 n. 1, p. 50-53 How to Cite?
AbstractGranulocytic sarcoma (GS) is a rare manifestation of acute myeloid leukemia (AML), blastic transformation of chronic myeloid leukemia, and the myelodysplastic syndromes. The mediastinum is an unusual site of presentation. We report a series of three female patients with mediastinal GS. They were characterized by the presence of large and bizarre blast cells and near tetraploidy on cytogenetic analysis. All three patients responded poorly to chemotherapy. Near tetraploid AML is a rare entity, usually present in male patients, and has not been associated with GS. The clinical and pathological similarities in these three cases suggest a distinct category of poor-risk AML for which more intensive treatment is needed.
Persistent Identifierhttp://hdl.handle.net/10722/162249
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_US
dc.contributor.authorMa, SKen_US
dc.contributor.authorChan, ACLen_US
dc.contributor.authorLiang, Ren_US
dc.contributor.authorLam, CCKen_US
dc.contributor.authorKwong, YLen_US
dc.date.accessioned2012-09-05T05:18:23Z-
dc.date.available2012-09-05T05:18:23Z-
dc.date.issued1998en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 1998, v. 102 n. 1, p. 50-53en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/162249-
dc.description.abstractGranulocytic sarcoma (GS) is a rare manifestation of acute myeloid leukemia (AML), blastic transformation of chronic myeloid leukemia, and the myelodysplastic syndromes. The mediastinum is an unusual site of presentation. We report a series of three female patients with mediastinal GS. They were characterized by the presence of large and bizarre blast cells and near tetraploidy on cytogenetic analysis. All three patients responded poorly to chemotherapy. Near tetraploid AML is a rare entity, usually present in male patients, and has not been associated with GS. The clinical and pathological similarities in these three cases suggest a distinct category of poor-risk AML for which more intensive treatment is needed.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.rightsCancer Genetics and Cytogenetics. Copyright © Elsevier Inc.-
dc.subject.meshAdulten_US
dc.subject.meshBone Marrow - Pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunophenotypingen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshLeukemia, Myeloid - Geneticsen_US
dc.subject.meshLeukemia, Myeloid, Acute - Genetics - Pathologyen_US
dc.subject.meshMediastinal Neoplasms - Geneticsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPolyploidyen_US
dc.titleNear tetraploidy in three cases of acute myeloid leukemia associated with mediastinal granulocytic sarcomaen_US
dc.typeArticleen_US
dc.identifier.emailLiang, R:rliang@hku.hken_US
dc.identifier.emailKwong, YL:ylkwong@hku.hken_US
dc.identifier.authorityLiang, R=rp00345en_US
dc.identifier.authorityKwong, YL=rp00358en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(97)00294-Xen_US
dc.identifier.pmid9530340-
dc.identifier.scopuseid_2-s2.0-0032053929en_US
dc.identifier.hkuros31149-
dc.identifier.hkuros41945-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032053929&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume102en_US
dc.identifier.issue1en_US
dc.identifier.spage50en_US
dc.identifier.epage53en_US
dc.identifier.isiWOS:000072661600010-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridAu, WY=7202383089en_US
dc.identifier.scopusauthoridMa, SK=37020910400en_US
dc.identifier.scopusauthoridChan, ACL=16047349300en_US
dc.identifier.scopusauthoridLiang, R=26643224900en_US
dc.identifier.scopusauthoridLam, CCK=16947291300en_US
dc.identifier.scopusauthoridKwong, YL=7102818954en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats