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Article: Clearance of persistent hepatitis B virus infection in chinese bone marrow transplant recipients whose donors were anti-hepatitis B core- and anti-hepatitis B surface antibody-positive
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TitleClearance of persistent hepatitis B virus infection in chinese bone marrow transplant recipients whose donors were anti-hepatitis B core- and anti-hepatitis B surface antibody-positive
 
AuthorsLau, GKK1
Liang, R
Lee, CK
Yuen, ST
Hou, J
Lim, WL
Williams, R
 
Issue Date1998
 
PublisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
 
CitationJournal Of Infectious Diseases, 1998, v. 178 n. 6, p. 1585-1591 [How to Cite?]
DOI: http://dx.doi.org/10.1086/314497
 
AbstractThirteen hepatitis B surface antigen-positive Chinese patients who received hepatitis B surface antibody-positive marrow (hepatitis B core antibody-positive or -negative: 6 and 7, respectively) via allogeneic bone marrow transplantation (BMT) were studied. After BMT, 4 recipients had serologic clearance of hepatitis B surface antigen from hepatitis B 'core antibody-positive marrow, but none of the recipients of hepatitis B core antibody-negative marrow had serologic clearance (P = .02). There was no significant difference in the donors' hepatitis B surface antibody triter before BMT for patients with or without serologic clearance of hepatitis B surface antigen (2255.2 ± 4244.0 vs. 854.2 ± 2306.7 mIU/mL; P = not significant). Adoptive immunity clearance of hepatitis B surface antigen was favored by hepatitis B core antibody positive-donor marrow and was not related to donor pre-BMT hepatitis B surface antibody titer.
 
ISSN0022-1899
2012 Impact Factor: 5.848
2012 SCImago Journal Rankings: 2.723
 
DOIhttp://dx.doi.org/10.1086/314497
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLau, GKK
 
dc.contributor.authorLiang, R
 
dc.contributor.authorLee, CK
 
dc.contributor.authorYuen, ST
 
dc.contributor.authorHou, J
 
dc.contributor.authorLim, WL
 
dc.contributor.authorWilliams, R
 
dc.date.accessioned2012-09-05T05:18:14Z
 
dc.date.available2012-09-05T05:18:14Z
 
dc.date.issued1998
 
dc.description.abstractThirteen hepatitis B surface antigen-positive Chinese patients who received hepatitis B surface antibody-positive marrow (hepatitis B core antibody-positive or -negative: 6 and 7, respectively) via allogeneic bone marrow transplantation (BMT) were studied. After BMT, 4 recipients had serologic clearance of hepatitis B surface antigen from hepatitis B 'core antibody-positive marrow, but none of the recipients of hepatitis B core antibody-negative marrow had serologic clearance (P = .02). There was no significant difference in the donors' hepatitis B surface antibody triter before BMT for patients with or without serologic clearance of hepatitis B surface antigen (2255.2 ± 4244.0 vs. 854.2 ± 2306.7 mIU/mL; P = not significant). Adoptive immunity clearance of hepatitis B surface antigen was favored by hepatitis B core antibody positive-donor marrow and was not related to donor pre-BMT hepatitis B surface antibody titer.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Infectious Diseases, 1998, v. 178 n. 6, p. 1585-1591 [How to Cite?]
DOI: http://dx.doi.org/10.1086/314497
 
dc.identifier.doihttp://dx.doi.org/10.1086/314497
 
dc.identifier.epage1591
 
dc.identifier.issn0022-1899
2012 Impact Factor: 5.848
2012 SCImago Journal Rankings: 2.723
 
dc.identifier.issue6
 
dc.identifier.pmid9815208
 
dc.identifier.scopuseid_2-s2.0-0031767805
 
dc.identifier.spage1585
 
dc.identifier.urihttp://hdl.handle.net/10722/162225
 
dc.identifier.volume178
 
dc.languageeng
 
dc.publisherOxford University Press. The Journal's web site is located at http://jid.oxfordjournals.org
 
dc.publisher.placeUnited States
 
dc.relation.ispartofJournal of Infectious Diseases
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshAdolescent
 
dc.subject.meshAdult
 
dc.subject.meshBone Marrow - Immunology
 
dc.subject.meshBone Marrow Transplantation - Adverse Effects - Immunology
 
dc.subject.meshChild
 
dc.subject.meshChina - Ethnology
 
dc.subject.meshDna, Viral - Blood
 
dc.subject.meshFemale
 
dc.subject.meshHepatitis B - Immunology - Transmission
 
dc.subject.meshHepatitis B Antibodies - Blood
 
dc.subject.meshHepatitis B Core Antigens - Analysis - Immunology
 
dc.subject.meshHepatitis B Surface Antigens - Analysis - Blood - Immunology
 
dc.subject.meshHepatitis B E Antigens - Analysis
 
dc.subject.meshHepatitis B Virus - Isolation & Purification
 
dc.subject.meshHong Kong
 
dc.subject.meshHumans
 
dc.subject.meshLiver Diseases - Etiology
 
dc.subject.meshLiving Donors
 
dc.subject.meshMale
 
dc.subject.meshMiddle Aged
 
dc.subject.meshPostoperative Complications
 
dc.subject.meshRetrospective Studies
 
dc.subject.meshReverse Transcriptase Polymerase Chain Reaction
 
dc.subject.meshTransplantation, Homologous
 
dc.titleClearance of persistent hepatitis B virus infection in chinese bone marrow transplant recipients whose donors were anti-hepatitis B core- and anti-hepatitis B surface antibody-positive
 
dc.typeArticle
 
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<contributor.author>Hou, J</contributor.author>
<contributor.author>Lim, WL</contributor.author>
<contributor.author>Williams, R</contributor.author>
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<description.abstract>Thirteen hepatitis B surface antigen-positive Chinese patients who received hepatitis B surface antibody-positive marrow (hepatitis B core antibody-positive or -negative: 6 and 7, respectively) via allogeneic bone marrow transplantation (BMT) were studied. After BMT, 4 recipients had serologic clearance of hepatitis B surface antigen from hepatitis B &apos;core antibody-positive marrow, but none of the recipients of hepatitis B core antibody-negative marrow had serologic clearance (P = .02). There was no significant difference in the donors&apos; hepatitis B surface antibody triter before BMT for patients with or without serologic clearance of hepatitis B surface antigen (2255.2 &#177; 4244.0 vs. 854.2 &#177; 2306.7 mIU/mL; P = not significant). Adoptive immunity clearance of hepatitis B surface antigen was favored by hepatitis B core antibody positive-donor marrow and was not related to donor pre-BMT hepatitis B surface antibody titer.</description.abstract>
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Author Affiliations
  1. The University of Hong Kong