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Article: Gene therapy-perspectives and promises

TitleGene therapy-perspectives and promises
Authors
KeywordsAdenoviruses, Human
Dna, Recombinant
Gene Therapy
Gene Vectors
Genes, Synthetic
Genetic Engineering
Genetic Markers
Hereditary Diseases
Issue Date1997
PublisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.html
Citation
Hong Kong Medical Journal, 1997, v. 3 n. 2, p. 163-172 How to Cite?
AbstractGene therapy is a novel and promising treatment for inherited and acquired genetic disorders. Basic laboratory investigations and clinical trials have shown that gene therapy in vivo is feasible, results in biological responses, and is relevant to different types of human diseases. To achieve clinical efficacy, current research has focused on improving the efficiency and specificity of gene transfer. Furthermore, gene therapy unlocks new research approaches and offers important insights into disease mechanisms. The emphasis of gene therapy has also shifted from the treatment of inherited genetic diseases to cancer. Despite the significant progress made in our understanding of gene therapy, considerable conceptual and practical limitations still exist. Evidence of the efficacy of gene therapy, however, is compelling. Many of the current problems of gene therapy should be overcome and gene therapy will become an important treatment modality for genetic diseases.
Persistent Identifierhttp://hdl.handle.net/10722/162181
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorKwong, YLen_US
dc.date.accessioned2012-09-05T05:17:52Z-
dc.date.available2012-09-05T05:17:52Z-
dc.date.issued1997en_US
dc.identifier.citationHong Kong Medical Journal, 1997, v. 3 n. 2, p. 163-172en_US
dc.identifier.issn1024-2708en_US
dc.identifier.urihttp://hdl.handle.net/10722/162181-
dc.description.abstractGene therapy is a novel and promising treatment for inherited and acquired genetic disorders. Basic laboratory investigations and clinical trials have shown that gene therapy in vivo is feasible, results in biological responses, and is relevant to different types of human diseases. To achieve clinical efficacy, current research has focused on improving the efficiency and specificity of gene transfer. Furthermore, gene therapy unlocks new research approaches and offers important insights into disease mechanisms. The emphasis of gene therapy has also shifted from the treatment of inherited genetic diseases to cancer. Despite the significant progress made in our understanding of gene therapy, considerable conceptual and practical limitations still exist. Evidence of the efficacy of gene therapy, however, is compelling. Many of the current problems of gene therapy should be overcome and gene therapy will become an important treatment modality for genetic diseases.en_US
dc.languageengen_US
dc.publisherHong Kong Medical Association. The Journal's web site is located at http://www.hkmj.org/resources/supp.htmlen_US
dc.relation.ispartofHong Kong Medical Journalen_US
dc.subjectAdenoviruses, Humanen_US
dc.subjectDna, Recombinanten_US
dc.subjectGene Therapyen_US
dc.subjectGene Vectorsen_US
dc.subjectGenes, Syntheticen_US
dc.subjectGenetic Engineeringen_US
dc.subjectGenetic Markersen_US
dc.subjectHereditary Diseasesen_US
dc.titleGene therapy-perspectives and promisesen_US
dc.typeArticleen_US
dc.identifier.emailKwong, YL:ylkwong@hku.hken_US
dc.identifier.authorityKwong, YL=rp00358en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0030770751en_US
dc.identifier.volume3en_US
dc.identifier.issue2en_US
dc.identifier.spage163en_US
dc.identifier.epage172en_US
dc.publisher.placeHong Kongen_US
dc.identifier.scopusauthoridKwong, YL=7102818954en_US

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