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Article: A new calcitonin-receptor-like sequence in rat pulmonary blood vessels

TitleA new calcitonin-receptor-like sequence in rat pulmonary blood vessels
Authors
Issue Date1993
PublisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/
Citation
Clinical Science, 1993, v. 85 n. 4, p. 385-388 How to Cite?
Abstract1. Two rat clones have been isolated which are similar to known calcitonin-receptor sequences. One of these does not have the distribution expected of a calcitonin receptor. It is widely distributed, with extremely high levels of expression in the lung, where it is associated with the blood vessels. 2. This rat sequence may represent the receptor for calcitonin-gene-related peptide or islet amyloid polypeptide. Both have binding activity in the lung and are potent vasodilators. The gene represented by this sequence may therefore play an important role in the maintenance of vascular tone.
Persistent Identifierhttp://hdl.handle.net/10722/161998
ISSN
2015 Impact Factor: 4.996
2015 SCImago Journal Rankings: 2.427
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNjuki, Fen_US
dc.contributor.authorNicholl, CGen_US
dc.contributor.authorHoward, Aen_US
dc.contributor.authorMak, JCWen_US
dc.contributor.authorBarnes, PJen_US
dc.contributor.authorGirgis, SIen_US
dc.contributor.authorLegon, Sen_US
dc.date.accessioned2012-09-05T05:16:33Z-
dc.date.available2012-09-05T05:16:33Z-
dc.date.issued1993en_US
dc.identifier.citationClinical Science, 1993, v. 85 n. 4, p. 385-388en_US
dc.identifier.issn0143-5221en_US
dc.identifier.urihttp://hdl.handle.net/10722/161998-
dc.description.abstract1. Two rat clones have been isolated which are similar to known calcitonin-receptor sequences. One of these does not have the distribution expected of a calcitonin receptor. It is widely distributed, with extremely high levels of expression in the lung, where it is associated with the blood vessels. 2. This rat sequence may represent the receptor for calcitonin-gene-related peptide or islet amyloid polypeptide. Both have binding activity in the lung and are potent vasodilators. The gene represented by this sequence may therefore play an important role in the maintenance of vascular tone.en_US
dc.languageengen_US
dc.publisherPortland Press Ltd. The Journal's web site is located at http://www.clinsci.org/en_US
dc.relation.ispartofClinical Scienceen_US
dc.subject.meshAmino Acid Sequenceen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBlotting, Northernen_US
dc.subject.meshIn Situ Hybridizationen_US
dc.subject.meshLung - Blood Supplyen_US
dc.subject.meshMaleen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshRna Probesen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshReceptors, Calcitonin - Chemistryen_US
dc.titleA new calcitonin-receptor-like sequence in rat pulmonary blood vesselsen_US
dc.typeArticleen_US
dc.identifier.emailMak, JCW:judymak@hku.hken_US
dc.identifier.authorityMak, JCW=rp00352en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8222502-
dc.identifier.scopuseid_2-s2.0-0027440296en_US
dc.identifier.volume85en_US
dc.identifier.issue4en_US
dc.identifier.spage385en_US
dc.identifier.epage388en_US
dc.identifier.isiWOS:A1993MB53400002-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridNjuki, F=55274777700en_US
dc.identifier.scopusauthoridNicholl, CG=7003731908en_US
dc.identifier.scopusauthoridHoward, A=7402702382en_US
dc.identifier.scopusauthoridMak, JCW=7103323094en_US
dc.identifier.scopusauthoridBarnes, PJ=36064679400en_US
dc.identifier.scopusauthoridGirgis, SI=35450026700en_US
dc.identifier.scopusauthoridLegon, S=7004036350en_US

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