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Article: Secondary central nervous system involvement by non-Hodgkin's lymphoma: The risk factors

TitleSecondary central nervous system involvement by non-Hodgkin's lymphoma: The risk factors
Authors
Issue Date1990
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182
Citation
Hematological Oncology, 1990, v. 8 n. 3, p. 141-145 How to Cite?
AbstractThe risk of secondary central nervous system (CNS) was estimated in 833 cases of non-Hodgkin's lymphoma diagnosed between January 1975 and December 1988. Fifty-one of them had CNS disease (51/833, 6.1 per cent). No case of low grade lymphoma developed CNS disease. However, 6.5 per cent and 16.7 per cent of patients with intermediate and high grade lymphomas, respectively, had secondary CNS involvement. Stage IV disease and the presence of B symptoms were also associated with an increased risk of CNS disease. Significantly higher incidence of CNS disease was seen in patients with lymphoma involving orbit (43 per cent), testis (40 per cent), peripheral blood (33 per cent), bone (29 per cent), nasal/paranasal sinuses region (23 per cent) and bone marrow (20 per cent). CNS prophylaxis is recommended to patients with an increased riks of CNS disease.
Persistent Identifierhttp://hdl.handle.net/10722/161814
ISSN
2015 Impact Factor: 3.494
2015 SCImago Journal Rankings: 0.767

 

DC FieldValueLanguage
dc.contributor.authorLiang, Ren_US
dc.contributor.authorChiu, Een_US
dc.contributor.authorLoke, SLen_US
dc.date.accessioned2012-09-05T05:15:14Z-
dc.date.available2012-09-05T05:15:14Z-
dc.date.issued1990en_US
dc.identifier.citationHematological Oncology, 1990, v. 8 n. 3, p. 141-145en_US
dc.identifier.issn0278-0232en_US
dc.identifier.urihttp://hdl.handle.net/10722/161814-
dc.description.abstractThe risk of secondary central nervous system (CNS) was estimated in 833 cases of non-Hodgkin's lymphoma diagnosed between January 1975 and December 1988. Fifty-one of them had CNS disease (51/833, 6.1 per cent). No case of low grade lymphoma developed CNS disease. However, 6.5 per cent and 16.7 per cent of patients with intermediate and high grade lymphomas, respectively, had secondary CNS involvement. Stage IV disease and the presence of B symptoms were also associated with an increased risk of CNS disease. Significantly higher incidence of CNS disease was seen in patients with lymphoma involving orbit (43 per cent), testis (40 per cent), peripheral blood (33 per cent), bone (29 per cent), nasal/paranasal sinuses region (23 per cent) and bone marrow (20 per cent). CNS prophylaxis is recommended to patients with an increased riks of CNS disease.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182en_US
dc.relation.ispartofHematological Oncologyen_US
dc.subject.meshBrain Neoplasms - Pathology - Secondaryen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphoma, Non-Hodgkin - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMeningeal Neoplasms - Pathology - Secondaryen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Stagingen_US
dc.titleSecondary central nervous system involvement by non-Hodgkin's lymphoma: The risk factorsen_US
dc.typeArticleen_US
dc.identifier.emailLiang, R:rliang@hku.hken_US
dc.identifier.authorityLiang, R=rp00345en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/hon.2900080305en_US
dc.identifier.pmid2373491-
dc.identifier.scopuseid_2-s2.0-0024991531en_US
dc.identifier.volume8en_US
dc.identifier.issue3en_US
dc.identifier.spage141en_US
dc.identifier.epage145en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLiang, R=26643224900en_US
dc.identifier.scopusauthoridChiu, E=24827833600en_US
dc.identifier.scopusauthoridLoke, SL=7006559512en_US

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