File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Glucose and lipid metabolism with triphasic oral contraceptive in women with history of gestational diabetes

TitleGlucose and lipid metabolism with triphasic oral contraceptive in women with history of gestational diabetes
Authors
Issue Date1987
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/contraception
Citation
Contraception, 1987, v. 35 n. 3, p. 257-269 How to Cite?
AbstractThe glucose and lipid metabolism in a group of 20 women with a previous history of gestational diabetes were evaluated before and after 6 months of treatment with a low-dose triphasic oral contraceptive (OC). Another group of 5 women, also with a history of gestational diabetes but who were given an IUD, served as controls. 26.7% of the women in the triphasic OC group developed impaired glucose tolerance; however, values reverted to normal in all but 1 woman after OC discontinuation. The IUD group showed no change in glucose tolerance. The integrated insulin response to a 75 gm oral glucose tolerance test increased by 48.3% at 6 months in the OC group compared with an increase of 23.4% for the same period in the control group. Also recorded in the OC group but not among controls was a significant increase in serum total cholesterol without changes in high density lipoprotein-cholesterol and triglyceride levels. It was concluded that even low-dose triphasic OCs can cause glucose intolerance in women with previous gestational diabetes mellitus. Thus, the theoretical risk of precipitating permanent diabetes should be weighed against the risk of pregnancy. In cases where OCs are the only reliable method possible, careful and frequent monitoring of carbohydrate metabolism should be performed. Older, heavier women with a family history of diabetes are in particular need of close surveillance and constant monitoring of their glucose and lipid metabolism.
Persistent Identifierhttp://hdl.handle.net/10722/161723
ISSN
2015 Impact Factor: 2.788
2015 SCImago Journal Rankings: 1.557
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKung, AWCen_US
dc.contributor.authorMa, JTCen_US
dc.contributor.authorWong, VCWen_US
dc.date.accessioned2012-09-05T05:14:21Z-
dc.date.available2012-09-05T05:14:21Z-
dc.date.issued1987en_US
dc.identifier.citationContraception, 1987, v. 35 n. 3, p. 257-269en_US
dc.identifier.issn0010-7824en_US
dc.identifier.urihttp://hdl.handle.net/10722/161723-
dc.description.abstractThe glucose and lipid metabolism in a group of 20 women with a previous history of gestational diabetes were evaluated before and after 6 months of treatment with a low-dose triphasic oral contraceptive (OC). Another group of 5 women, also with a history of gestational diabetes but who were given an IUD, served as controls. 26.7% of the women in the triphasic OC group developed impaired glucose tolerance; however, values reverted to normal in all but 1 woman after OC discontinuation. The IUD group showed no change in glucose tolerance. The integrated insulin response to a 75 gm oral glucose tolerance test increased by 48.3% at 6 months in the OC group compared with an increase of 23.4% for the same period in the control group. Also recorded in the OC group but not among controls was a significant increase in serum total cholesterol without changes in high density lipoprotein-cholesterol and triglyceride levels. It was concluded that even low-dose triphasic OCs can cause glucose intolerance in women with previous gestational diabetes mellitus. Thus, the theoretical risk of precipitating permanent diabetes should be weighed against the risk of pregnancy. In cases where OCs are the only reliable method possible, careful and frequent monitoring of carbohydrate metabolism should be performed. Older, heavier women with a family history of diabetes are in particular need of close surveillance and constant monitoring of their glucose and lipid metabolism.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/contraceptionen_US
dc.relation.ispartofContraceptionen_US
dc.subject.meshAdulten_US
dc.subject.meshBlood Glucose - Metabolismen_US
dc.subject.meshCholesterol - Blooden_US
dc.subject.meshContraceptives, Oral, Hormonal - Pharmacologyen_US
dc.subject.meshEthinyl Estradiol - Administration & Dosage - Pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulin - Blooden_US
dc.subject.meshLevonorgestrelen_US
dc.subject.meshLipids - Blooden_US
dc.subject.meshNorgestrel - Administration & Dosage - Pharmacologyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy In Diabeticsen_US
dc.titleGlucose and lipid metabolism with triphasic oral contraceptive in women with history of gestational diabetesen_US
dc.typeArticleen_US
dc.identifier.emailKung, AWC:awckung@hku.hken_US
dc.identifier.authorityKung, AWC=rp00368en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0010-7824(87)90027-8-
dc.identifier.pmid3111786-
dc.identifier.scopuseid_2-s2.0-0023179187en_US
dc.identifier.volume35en_US
dc.identifier.issue3en_US
dc.identifier.spage257en_US
dc.identifier.epage269en_US
dc.identifier.isiWOS:A1987H600200006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridKung, AWC=7102322339en_US
dc.identifier.scopusauthoridMa, JTC=24491943700en_US
dc.identifier.scopusauthoridWong, VCW=24381178900en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats