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Article: Combination of three α-globin gene loci deletions and hemoglobin New York results in a severe hemoglobin H syndrome

TitleCombination of three α-globin gene loci deletions and hemoglobin New York results in a severe hemoglobin H syndrome
Authors
Issue Date1987
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
Citation
American Journal Of Hematology, 1987, v. 24 n. 3, p. 301-306 How to Cite?
AbstractA Chinese patient with hemoglobin (Hb) H and Hb New York is described. Unlike classical Hb H disease, the additional β(New York) chain defect resulted in a more marked α/β-globin chain imbalance in this patient with only one α-gene, accounting for her severe anemia (3.4-6.8 g/dl) during the steady state.
Persistent Identifierhttp://hdl.handle.net/10722/161720
ISSN
2015 Impact Factor: 5.0
2015 SCImago Journal Rankings: 1.761
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, Ven_US
dc.contributor.authorChan, TKen_US
dc.contributor.authorTso, SCen_US
dc.contributor.authorTodd, Den_US
dc.date.accessioned2012-09-05T05:14:20Z-
dc.date.available2012-09-05T05:14:20Z-
dc.date.issued1987en_US
dc.identifier.citationAmerican Journal Of Hematology, 1987, v. 24 n. 3, p. 301-306en_US
dc.identifier.issn0361-8609en_US
dc.identifier.urihttp://hdl.handle.net/10722/161720-
dc.description.abstractA Chinese patient with hemoglobin (Hb) H and Hb New York is described. Unlike classical Hb H disease, the additional β(New York) chain defect resulted in a more marked α/β-globin chain imbalance in this patient with only one α-gene, accounting for her severe anemia (3.4-6.8 g/dl) during the steady state.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105en_US
dc.relation.ispartofAmerican Journal of Hematologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAnemia - Genetics - Therapyen_US
dc.subject.meshBlood Transfusionen_US
dc.subject.meshChromosome Deletionen_US
dc.subject.meshDna - Analysisen_US
dc.subject.meshErythrocyte Agingen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlobins - Biosynthesis - Geneticsen_US
dc.subject.meshHemoglobins, Abnormal - Analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshThalassemia - Etiology - Geneticsen_US
dc.titleCombination of three α-globin gene loci deletions and hemoglobin New York results in a severe hemoglobin H syndromeen_US
dc.typeArticleen_US
dc.identifier.emailChan, V:vnychana@hkucc.hku.hken_US
dc.identifier.authorityChan, V=rp00320en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/ajh.2830240310-
dc.identifier.pmid3826056en_US
dc.identifier.scopuseid_2-s2.0-0023149461en_US
dc.identifier.volume24en_US
dc.identifier.issue3en_US
dc.identifier.spage301en_US
dc.identifier.epage306en_US
dc.identifier.isiWOS:A1987G351500009-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChan, V=7202654865en_US
dc.identifier.scopusauthoridChan, TK=7402687762en_US
dc.identifier.scopusauthoridTso, SC=7103261600en_US
dc.identifier.scopusauthoridTodd, D=7201388182en_US

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