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Article: Incidence of hypothyroidism after radioactive iodine therapy for thyrotoxicosis in Hong Kong Chinese

TitleIncidence of hypothyroidism after radioactive iodine therapy for thyrotoxicosis in Hong Kong Chinese
Authors
Issue Date1981
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/crad
Citation
Clinical Radiology, 1981, v. 32 n. 1, p. 57-61 How to Cite?
AbstractThe incidence of hypothyroidism in 1396 Chinese patients in Hong Kong treated for hyperthyroidism with 131I therapy is presented using the life-table method of analysis. One year after therapy only 6% of patients were hypothyroid, but the subsequent annual incidence was 3.5%, emphasizing the need for life-time surveillance of these patients. A higher incidence of subsequent hypothyroidism was found in patients with diffuse compared with nodular glands and small (less than 40 g) compared with larger glands. Previous medical or surgical treatment, the total dose or number of doses of 131I, the severity of thyrotoxicosis and the age of the patient did not influence the rate of onset of hypothyroidism. The data suggest that in order to minimize the occurrence of hypothyroidism a lower dose of 131I per gram of thyroid mass should be used for patients with small diffuse glands.
Persistent Identifierhttp://hdl.handle.net/10722/161656
ISSN
2015 Impact Factor: 2.151
2015 SCImago Journal Rankings: 0.864
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorBest, JDen_US
dc.contributor.authorChan, Ven_US
dc.contributor.authorKhoo, Ren_US
dc.date.accessioned2012-09-05T05:13:35Z-
dc.date.available2012-09-05T05:13:35Z-
dc.date.issued1981en_US
dc.identifier.citationClinical Radiology, 1981, v. 32 n. 1, p. 57-61en_US
dc.identifier.issn0009-9260en_US
dc.identifier.urihttp://hdl.handle.net/10722/161656-
dc.description.abstractThe incidence of hypothyroidism in 1396 Chinese patients in Hong Kong treated for hyperthyroidism with 131I therapy is presented using the life-table method of analysis. One year after therapy only 6% of patients were hypothyroid, but the subsequent annual incidence was 3.5%, emphasizing the need for life-time surveillance of these patients. A higher incidence of subsequent hypothyroidism was found in patients with diffuse compared with nodular glands and small (less than 40 g) compared with larger glands. Previous medical or surgical treatment, the total dose or number of doses of 131I, the severity of thyrotoxicosis and the age of the patient did not influence the rate of onset of hypothyroidism. The data suggest that in order to minimize the occurrence of hypothyroidism a lower dose of 131I per gram of thyroid mass should be used for patients with small diffuse glands.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/craden_US
dc.relation.ispartofClinical Radiologyen_US
dc.subject.meshAdulten_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshHyperthyroidism - Radiotherapyen_US
dc.subject.meshHypothyroidism - Etiologyen_US
dc.subject.meshIodine Radioisotopes - Adverse Effects - Therapeutic Useen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRadiation Injuries - Etiologyen_US
dc.subject.meshRadiotherapy - Adverse Effectsen_US
dc.subject.meshRadiotherapy Dosageen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTime Factorsen_US
dc.titleIncidence of hypothyroidism after radioactive iodine therapy for thyrotoxicosis in Hong Kong Chineseen_US
dc.typeArticleen_US
dc.identifier.emailChan, V:vnychana@hkucc.hku.hken_US
dc.identifier.authorityChan, V=rp00320en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0009-9260(81)80253-X-
dc.identifier.pmid7214823-
dc.identifier.scopuseid_2-s2.0-0019367726en_US
dc.identifier.volume32en_US
dc.identifier.issue1en_US
dc.identifier.spage57en_US
dc.identifier.epage61en_US
dc.identifier.isiWOS:A1981KY23700009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridBest, JD=24524703400en_US
dc.identifier.scopusauthoridChan, V=7202654865en_US
dc.identifier.scopusauthoridKhoo, R=6701680249en_US

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