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Article: Effects of heroin addiction on thyrotrophin, thyroid hormones and prolactin secretion in men

TitleEffects of heroin addiction on thyrotrophin, thyroid hormones and prolactin secretion in men
Authors
Issue Date1979
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664
Citation
Clinical Endocrinology, 1979, v. 10 n. 6, p. 557-565 How to Cite?
AbstractPituitary-thyroid function in male heroin addicts and addicts after abstinence (ex-addicts) was studied and compared with that of healthy euthyroid men. In heroin addicts the increases in circulating total thyroxine and triiodothyronine levels were accompanied by an increase in the thyroid hormone uptake test. These changes may reflect a quantitative increase in thyroxine binding globulin. Reverse triidothyronine concentrations in heroin addicts were normal. The thyrotrophin-releasing hormone elicited a diminished thyrotrophin response in heroin addicts which was significantly different from that in control subjects and ex-addicts. An elevation of serum prolactin was noted in heroin addicts, while ex-addicts had normal levels. Gradual recovery of pituitary-thyroid function occurred after heroin withdrawal.
Persistent Identifierhttp://hdl.handle.net/10722/161645
ISSN
2015 Impact Factor: 3.487
2015 SCImago Journal Rankings: 1.314
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, Ven_US
dc.contributor.authorWang, Cen_US
dc.contributor.authorYeung, RTTen_US
dc.date.accessioned2012-09-05T05:13:28Z-
dc.date.available2012-09-05T05:13:28Z-
dc.date.issued1979en_US
dc.identifier.citationClinical Endocrinology, 1979, v. 10 n. 6, p. 557-565en_US
dc.identifier.issn0300-0664en_US
dc.identifier.urihttp://hdl.handle.net/10722/161645-
dc.description.abstractPituitary-thyroid function in male heroin addicts and addicts after abstinence (ex-addicts) was studied and compared with that of healthy euthyroid men. In heroin addicts the increases in circulating total thyroxine and triiodothyronine levels were accompanied by an increase in the thyroid hormone uptake test. These changes may reflect a quantitative increase in thyroxine binding globulin. Reverse triidothyronine concentrations in heroin addicts were normal. The thyrotrophin-releasing hormone elicited a diminished thyrotrophin response in heroin addicts which was significantly different from that in control subjects and ex-addicts. An elevation of serum prolactin was noted in heroin addicts, while ex-addicts had normal levels. Gradual recovery of pituitary-thyroid function occurred after heroin withdrawal.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664en_US
dc.relation.ispartofClinical Endocrinologyen_US
dc.subject.meshAdulten_US
dc.subject.meshHeroin Dependence - Blood - Physiopathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshProlactin - Blood - Secretionen_US
dc.subject.meshThyrotropin - Blood - Secretionen_US
dc.subject.meshThyrotropin-Releasing Hormone - Diagnostic Useen_US
dc.subject.meshThyroxine - Blood - Secretionen_US
dc.subject.meshTriiodothyronine - Blood - Secretionen_US
dc.subject.meshTriiodothyronine, Reverse - Blood - Secretionen_US
dc.titleEffects of heroin addiction on thyrotrophin, thyroid hormones and prolactin secretion in menen_US
dc.typeArticleen_US
dc.identifier.emailChan, V:vnychana@hkucc.hku.hken_US
dc.identifier.authorityChan, V=rp00320en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1365-2265.1979.tb02115.x-
dc.identifier.pmid113145-
dc.identifier.scopuseid_2-s2.0-0018640028en_US
dc.identifier.volume10en_US
dc.identifier.issue6en_US
dc.identifier.spage557en_US
dc.identifier.epage565en_US
dc.identifier.isiWOS:A1979HB41800003-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, V=7202654865en_US
dc.identifier.scopusauthoridWang, C=7501631357en_US
dc.identifier.scopusauthoridYeung, RTT=7102833337en_US

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