File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Silkworm powder containing manganese superoxide dismutase regulated the immunity and inhibited the growth of Hepatoma 22 cell in mice

TitleSilkworm powder containing manganese superoxide dismutase regulated the immunity and inhibited the growth of Hepatoma 22 cell in mice
Authors
Issue Date2009
PublisherSpringer Verlag Dordrecht. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0301-4851
Citation
Molecular Biology Reports, 2009, v. 36 n. 2, p. 323-328 How to Cite?
AbstractThe effects of SOD contained silkworm powder on immune regulation and inhibition against Hepatoma 22 tumor cells in vivo were investigated. The activity of natural killer cell (NK) and the ConA-stimulated spleen proliferation were measured. The results found that the SOD-contained silkworm powder caused an enhancement on NK cell activity, which implied this material modulated the immune system in mice in vivo. The NK cell activities of Hepatoma 22 tumor modeled mice treated with silkworm powder including SOD were increased significantly compared to a modeled control and silkworm powder without SOD, reaching 36.18%. In addition, the ConA-stimulated spleen proliferation of SOD treated mice was higher than that of the controls. The treatment of SOD contained silkworm powder presented 40.3% of average inhibition rate to Hepatoma 22 tumor, showing stronger inhibition against tumor. There were no significant difference in body weight between modeled control and SOD silkworm powder feeding in Hepatoma 22 tumor modeled mice, suggesting the SOD silkworm powder is safety as an inhibitant to tumor. In conclusion, these findings demonstrate that administration of silkworm powder containing SOD results in activation of NK cells and immunity, suggesting the silkworm powder containing SOD plays a positive role in tumor inhibition. © 2007 Springer Science+Business Media B.V.
Persistent Identifierhttp://hdl.handle.net/10722/161285
ISSN
2015 Impact Factor: 1.698
2015 SCImago Journal Rankings: 0.730
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYue, WFen_US
dc.contributor.authorDeng, Wen_US
dc.contributor.authorLi, XHen_US
dc.contributor.authorRoy, Ben_US
dc.contributor.authorLi, GLen_US
dc.contributor.authorLiu, JMen_US
dc.contributor.authorWu, XFen_US
dc.contributor.authorSun, HXen_US
dc.contributor.authorYao, MLen_US
dc.contributor.authorDavid, WCCen_US
dc.contributor.authorMiao, YGen_US
dc.date.accessioned2012-08-24T08:29:27Z-
dc.date.available2012-08-24T08:29:27Z-
dc.date.issued2009en_US
dc.identifier.citationMolecular Biology Reports, 2009, v. 36 n. 2, p. 323-328en_US
dc.identifier.issn0301-4851en_US
dc.identifier.urihttp://hdl.handle.net/10722/161285-
dc.description.abstractThe effects of SOD contained silkworm powder on immune regulation and inhibition against Hepatoma 22 tumor cells in vivo were investigated. The activity of natural killer cell (NK) and the ConA-stimulated spleen proliferation were measured. The results found that the SOD-contained silkworm powder caused an enhancement on NK cell activity, which implied this material modulated the immune system in mice in vivo. The NK cell activities of Hepatoma 22 tumor modeled mice treated with silkworm powder including SOD were increased significantly compared to a modeled control and silkworm powder without SOD, reaching 36.18%. In addition, the ConA-stimulated spleen proliferation of SOD treated mice was higher than that of the controls. The treatment of SOD contained silkworm powder presented 40.3% of average inhibition rate to Hepatoma 22 tumor, showing stronger inhibition against tumor. There were no significant difference in body weight between modeled control and SOD silkworm powder feeding in Hepatoma 22 tumor modeled mice, suggesting the SOD silkworm powder is safety as an inhibitant to tumor. In conclusion, these findings demonstrate that administration of silkworm powder containing SOD results in activation of NK cells and immunity, suggesting the silkworm powder containing SOD plays a positive role in tumor inhibition. © 2007 Springer Science+Business Media B.V.en_US
dc.languageengen_US
dc.publisherSpringer Verlag Dordrecht. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0301-4851en_US
dc.relation.ispartofMolecular Biology Reportsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntineoplastic Agentsen_US
dc.subject.meshBombyxen_US
dc.subject.meshCell Line, Tumoren_US
dc.subject.meshCell Proliferation - Drug Effectsen_US
dc.subject.meshImmunity - Drug Effectsen_US
dc.subject.meshKiller Cells, Natural - Drug Effectsen_US
dc.subject.meshLiver Neoplasms, Experimental - Drug Therapy - Pathologyen_US
dc.subject.meshMiceen_US
dc.subject.meshPowdersen_US
dc.subject.meshSuperoxide Dismutase - Administration & Dosage - Therapeutic Useen_US
dc.titleSilkworm powder containing manganese superoxide dismutase regulated the immunity and inhibited the growth of Hepatoma 22 cell in miceen_US
dc.typeArticleen_US
dc.identifier.emailDeng, W:wdeng@hkucc.hku.hken_US
dc.identifier.authorityDeng, W=rp01640en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s11033-007-9182-3en_US
dc.identifier.pmid18034371-
dc.identifier.scopuseid_2-s2.0-58149195657en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-58149195657&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume36en_US
dc.identifier.issue2en_US
dc.identifier.spage323en_US
dc.identifier.epage328en_US
dc.identifier.isiWOS:000262088300014-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridYue, WF=15023761100en_US
dc.identifier.scopusauthoridDeng, W=55160364700en_US
dc.identifier.scopusauthoridLi, XH=15053538900en_US
dc.identifier.scopusauthoridRoy, B=23006307200en_US
dc.identifier.scopusauthoridLi, GL=15022539100en_US
dc.identifier.scopusauthoridLiu, JM=36080186400en_US
dc.identifier.scopusauthoridWu, XF=8597657000en_US
dc.identifier.scopusauthoridSun, HX=7404827412en_US
dc.identifier.scopusauthoridYao, ML=36852630300en_US
dc.identifier.scopusauthoridDavid, WCC=23003961300en_US
dc.identifier.scopusauthoridMiao, YG=7101982264en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats