File Download
  • No File Attached
 
 
Supplementary

Article: Comparision of Two Determination Methods for Astragaloside Ⅳ in Radix Astragali
  • Basic View
  • Metadata View
  • XML View
TitleComparision of Two Determination Methods for Astragaloside Ⅳ in Radix Astragali
黃芪藥材中黃芪甲苷含量測定的兩種方法的比較研究
 
AuthorsLiu, H
Liu, J
yang, M
Chen, J
Wang, D
 
KeywordsVolatilization (揮發作用)
Astragalus membranaceus (黃芪)
Hong Kong (香港)
Pharmacopoeias (藥典)
Light (光)
 
Issue Date2012
 
PublisherGuangzhou University of Chinese Medicine (廣州中醫藥大學).
 
CitationTraditional Chinese Drug Research and Clinical Pharmacology, 2012, v. 22 n. 6, p. 659-662
中药新药与临床药理, 2012, v. 22 n. 6, p. 659-662 [How to Cite?]
 
Abstractobjective To simplify the sample preparation method and to establish a rapid and accurate method for detemination of astragaloside IV in Radix Astragali. Methods Two methods described in Chinese Pharmacopoeia (2010)(ChP) and Hong Kong Chinese Materia Medica Standards(2005)(HKCMMS)were compared.Results: The content of astragaloside IV determined by HKCMMS showed a good linearity in the range of 20.56 411.20 μg/mL. The average recovery was 102.14% and RSD was 3.1%. SPSS 13.0 software was used for the statistical analysis of determination of astragaloside IV in 3 batches of Radix Astragali by the two methods, and T test results showed P= 0.951 > 0.05. Radix Astragali in 19 groups bought from Qingping market were determined by HKCMMS, and the results showed content of astragaloside IV was in the range of 0.15 0.84 mg/g. Conclusion The sample preparation method utilized in HKCMMS is simple, accurate, reliable and with good reproducibility, and there are no significant differences of the detemination results between Chp and HKCMMS.
目的 簡化樣品前處理方法,確立一種簡便快速、準確的黃芪藥材中黃芪甲苷的含量測定方法.方法 比較《中國藥典》和《香港中藥材標準》(港標)中黃芪甲苷的含量測定方法.結果 港標方法測定黃芪甲苷對照品濃度在20.56~411.20 μg/mL之間呈良好線性關系,r=0.9973.平均加樣回收率為102.14%,RSD為3.1%.采用SPSS 13.0軟件對兩種分析方法測得的3批藥材黃芪甲苷含量作統計分析,T檢驗結果P=0.951>0.05.采用港標方法對購自清平藥材市場19批藥材中黃芪甲苷含量進行測定,結果含量在0.15 ~ 0.84 mg/g之間.結論 港標方法重現性良好,結果準確可靠,且樣品前處理方法簡便,測得黃芪藥材中黃芪甲苷含量與中國藥典方法相比沒有統計學差異.
 
ISSN1003-9783
 
DC FieldValue
dc.contributor.authorLiu, H
 
dc.contributor.authorLiu, J
 
dc.contributor.authoryang, M
 
dc.contributor.authorChen, J
 
dc.contributor.authorWang, D
 
dc.date.accessioned2012-08-16T06:17:21Z
 
dc.date.available2012-08-16T06:17:21Z
 
dc.date.issued2012
 
dc.description.abstractobjective To simplify the sample preparation method and to establish a rapid and accurate method for detemination of astragaloside IV in Radix Astragali. Methods Two methods described in Chinese Pharmacopoeia (2010)(ChP) and Hong Kong Chinese Materia Medica Standards(2005)(HKCMMS)were compared.Results: The content of astragaloside IV determined by HKCMMS showed a good linearity in the range of 20.56 411.20 μg/mL. The average recovery was 102.14% and RSD was 3.1%. SPSS 13.0 software was used for the statistical analysis of determination of astragaloside IV in 3 batches of Radix Astragali by the two methods, and T test results showed P= 0.951 > 0.05. Radix Astragali in 19 groups bought from Qingping market were determined by HKCMMS, and the results showed content of astragaloside IV was in the range of 0.15 0.84 mg/g. Conclusion The sample preparation method utilized in HKCMMS is simple, accurate, reliable and with good reproducibility, and there are no significant differences of the detemination results between Chp and HKCMMS.
 
dc.description.abstract目的 簡化樣品前處理方法,確立一種簡便快速、準確的黃芪藥材中黃芪甲苷的含量測定方法.方法 比較《中國藥典》和《香港中藥材標準》(港標)中黃芪甲苷的含量測定方法.結果 港標方法測定黃芪甲苷對照品濃度在20.56~411.20 μg/mL之間呈良好線性關系,r=0.9973.平均加樣回收率為102.14%,RSD為3.1%.采用SPSS 13.0軟件對兩種分析方法測得的3批藥材黃芪甲苷含量作統計分析,T檢驗結果P=0.951>0.05.采用港標方法對購自清平藥材市場19批藥材中黃芪甲苷含量進行測定,結果含量在0.15 ~ 0.84 mg/g之間.結論 港標方法重現性良好,結果準確可靠,且樣品前處理方法簡便,測得黃芪藥材中黃芪甲苷含量與中國藥典方法相比沒有統計學差異.
 
dc.identifier.citationTraditional Chinese Drug Research and Clinical Pharmacology, 2012, v. 22 n. 6, p. 659-662
 
dc.identifier.citation中药新药与临床药理, 2012, v. 22 n. 6, p. 659-662 [How to Cite?]
 
dc.identifier.epage662
 
dc.identifier.hkuros203870
 
dc.identifier.issn1003-9783
 
dc.identifier.issue6
 
dc.identifier.spage659
 
dc.identifier.urihttp://hdl.handle.net/10722/160723
 
dc.identifier.volume22
 
dc.languageeng
 
dc.publisherGuangzhou University of Chinese Medicine (廣州中醫藥大學).
 
dc.publisher.placeGuangzhou (廣州)
 
dc.relation.ispartofTraditional Chinese Drug Research and Clinical Pharmacology
 
dc.relation.ispartof中药新药与临床药理
 
dc.subjectVolatilization (揮發作用)
 
dc.subjectAstragalus membranaceus (黃芪)
 
dc.subjectHong Kong (香港)
 
dc.subjectPharmacopoeias (藥典)
 
dc.subjectLight (光)
 
dc.titleComparision of Two Determination Methods for Astragaloside Ⅳ in Radix Astragali
 
dc.title黃芪藥材中黃芪甲苷含量測定的兩種方法的比較研究
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Liu, H</contributor.author>
<contributor.author>Liu, J</contributor.author>
<contributor.author>yang, M</contributor.author>
<contributor.author>Chen, J</contributor.author>
<contributor.author>Wang, D</contributor.author>
<date.accessioned>2012-08-16T06:17:21Z</date.accessioned>
<date.available>2012-08-16T06:17:21Z</date.available>
<date.issued>2012</date.issued>
<identifier.citation>Traditional Chinese Drug Research and Clinical Pharmacology, 2012, v. 22 n. 6, p. 659-662</identifier.citation>
<identifier.citation>&#20013;&#33647;&#26032;&#33647;&#19982;&#20020;&#24202;&#33647;&#29702;, 2012, v. 22 n. 6, p. 659-662</identifier.citation>
<identifier.issn>1003-9783</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/160723</identifier.uri>
<description.abstract>objective To simplify the sample preparation method and to establish a rapid and accurate method for
detemination of astragaloside IV in Radix Astragali. Methods Two methods described in Chinese Pharmacopoeia (2010)(ChP) and Hong Kong Chinese Materia Medica Standards(2005)(HKCMMS)were compared&#65294;Results: The content of astragaloside IV determined by HKCMMS showed a good linearity in the range of 20.56  411.20 &#956;g/mL. The average recovery was 102.14% and RSD was 3.1%. SPSS 13.0 software was used for the statistical analysis of determination of astragaloside IV in 3 batches of Radix Astragali by the two methods,  and T test results showed P= 0.951 &gt; 0.05. Radix Astragali in 19 groups bought from Qingping market were determined by HKCMMS, and the results showed content of astragaloside IV was in the range of 0.15  0.84 mg/g. Conclusion The sample preparation method utilized in HKCMMS is simple, accurate, reliable and with good reproducibility, and there are no significant differences of the detemination results between Chp and HKCMMS.</description.abstract>
<description.abstract>&#30446;&#30340; &#31777;&#21270;&#27171;&#21697;&#21069;&#34389;&#29702;&#26041;&#27861;,&#30906;&#31435;&#19968;&#31278;&#31777;&#20415;&#24555;&#36895;&#12289;&#28310;&#30906;&#30340;&#40643;&#33450;&#34277;&#26448;&#20013;&#40643;&#33450;&#30002;&#33527;&#30340;&#21547;&#37327;&#28204;&#23450;&#26041;&#27861;.&#26041;&#27861; &#27604;&#36611;&#12298;&#20013;&#22283;&#34277;&#20856;&#12299;&#21644;&#12298;&#39321;&#28207;&#20013;&#34277;&#26448;&#27161;&#28310;&#12299;(&#28207;&#27161;)&#20013;&#40643;&#33450;&#30002;&#33527;&#30340;&#21547;&#37327;&#28204;&#23450;&#26041;&#27861;.&#32080;&#26524; &#28207;&#27161;&#26041;&#27861;&#28204;&#23450;&#40643;&#33450;&#30002;&#33527;&#23565;&#29031;&#21697;&#28611;&#24230;&#22312;20.56&#65374;411.20 &#956;g/mL&#20043;&#38291;&#21576;&#33391;&#22909;&#32218;&#24615;&#38364;&#31995;,r=0.9973.&#24179;&#22343;&#21152;&#27171;&#22238;&#25910;&#29575;&#28858;102.14&#65285;,RSD&#28858;3.1&#65285;.&#37319;&#29992;SPSS 13.0&#36575;&#20214;&#23565;&#20841;&#31278;&#20998;&#26512;&#26041;&#27861;&#28204;&#24471;&#30340;3&#25209;&#34277;&#26448;&#40643;&#33450;&#30002;&#33527;&#21547;&#37327;&#20316;&#32113;&#35336;&#20998;&#26512;,T&#27298;&#39511;&#32080;&#26524;P=0.951&#65310;0.05.&#37319;&#29992;&#28207;&#27161;&#26041;&#27861;&#23565;&#36092;&#33258;&#28165;&#24179;&#34277;&#26448;&#24066;&#22580;19&#25209;&#34277;&#26448;&#20013;&#40643;&#33450;&#30002;&#33527;&#21547;&#37327;&#36914;&#34892;&#28204;&#23450;,&#32080;&#26524;&#21547;&#37327;&#22312;0.15 &#65374; 0.84 mg/g&#20043;&#38291;.&#32080;&#35542; &#28207;&#27161;&#26041;&#27861;&#37325;&#29694;&#24615;&#33391;&#22909;,&#32080;&#26524;&#28310;&#30906;&#21487;&#38752;,&#19988;&#27171;&#21697;&#21069;&#34389;&#29702;&#26041;&#27861;&#31777;&#20415;,&#28204;&#24471;&#40643;&#33450;&#34277;&#26448;&#20013;&#40643;&#33450;&#30002;&#33527;&#21547;&#37327;&#33287;&#20013;&#22283;&#34277;&#20856;&#26041;&#27861;&#30456;&#27604;&#27794;&#26377;&#32113;&#35336;&#23416;&#24046;&#30064;.</description.abstract>
<language>eng</language>
<publisher>Guangzhou University of Chinese Medicine (&#24291;&#24030;&#20013;&#37291;&#34277;&#22823;&#23416;).</publisher>
<relation.ispartof>Traditional Chinese Drug Research and Clinical Pharmacology</relation.ispartof>
<relation.ispartof>&#20013;&#33647;&#26032;&#33647;&#19982;&#20020;&#24202;&#33647;&#29702;</relation.ispartof>
<subject>Volatilization (&#25582;&#30332;&#20316;&#29992;)</subject>
<subject>Astragalus membranaceus (&#40643;&#33450;)</subject>
<subject>Hong Kong (&#39321;&#28207;)</subject>
<subject>Pharmacopoeias (&#34277;&#20856;)</subject>
<subject>Light (&#20809;)</subject>
<title>Comparision of Two Determination Methods for Astragaloside &#8547; in Radix Astragali</title>
<title>&#40643;&#33450;&#34277;&#26448;&#20013;&#40643;&#33450;&#30002;&#33527;&#21547;&#37327;&#28204;&#23450;&#30340;&#20841;&#31278;&#26041;&#27861;&#30340;&#27604;&#36611;&#30740;&#31350;</title>
<type>Article</type>
<identifier.hkuros>203870</identifier.hkuros>
<identifier.volume>22</identifier.volume>
<identifier.issue>6</identifier.issue>
<identifier.spage>659</identifier.spage>
<identifier.epage>662</identifier.epage>
<publisher.place>Guangzhou (&#24291;&#24030;)</publisher.place>
</item>