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Conference Paper: Effects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat heart

TitleEffects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat heart
Authors
KeywordsMedical sciences
Respiratory diseases
Issue Date2012
PublisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.org
Citation
The 2012 International Conference of the American Thoracic Society, San Francisco, CA., 18-23 May 2012. In American Journal of Respiratory and Critical Care Medicine, 2012, v. 185 meeting abstracts, abstract A3869 How to Cite?
AbstractRATIONALE: Fatty acid-binding proteins (FABPs) are members of the lipid-binding proteins (LBPs) superfamily, regulating the fatty acid uptake and intercellular transport. Among 9 subtypes identified with tissue-specific distribution, serum A- and H-FABP have been found to be significantly higher in patients with obstructive sleep apnea (OSA) than in controls (Sleep Breath 2008;12:223-228; Eur Respir J 2009;33:346-351). Intermittent hypoxia (IH) is a hallmark feature in OSA, which is increasingly recognized as an independent risk factor of cardiovascular diseases (CVD). In this study, we hypothesized that IH could regulate both lipid parameters and the expression of specific ABPs leading to heart damage. We aimed to study systemic and cardiac lipid parameters and the specific expression of cardiac FABPs. METHODS: Male Sprague–Dawley rats …
DescriptionSession B109 Sleep Disordered Breathing and Cardiovascular Disease: Of Rodents and Humans
Poster Discussion Session
Open Access Journal
Persistent Identifierhttp://hdl.handle.net/10722/160340
ISSN
2015 Impact Factor: 13.118
2015 SCImago Journal Rankings: 5.832

 

DC FieldValueLanguage
dc.contributor.authorMak, JCWen_US
dc.contributor.authorHan, Qen_US
dc.contributor.authorYeung, SCen_US
dc.contributor.authorIp, MSMen_US
dc.date.accessioned2012-08-16T06:08:07Z-
dc.date.available2012-08-16T06:08:07Z-
dc.date.issued2012en_US
dc.identifier.citationThe 2012 International Conference of the American Thoracic Society, San Francisco, CA., 18-23 May 2012. In American Journal of Respiratory and Critical Care Medicine, 2012, v. 185 meeting abstracts, abstract A3869en_US
dc.identifier.issn1073-449X-
dc.identifier.urihttp://hdl.handle.net/10722/160340-
dc.descriptionSession B109 Sleep Disordered Breathing and Cardiovascular Disease: Of Rodents and Humans-
dc.descriptionPoster Discussion Session-
dc.descriptionOpen Access Journal-
dc.description.abstractRATIONALE: Fatty acid-binding proteins (FABPs) are members of the lipid-binding proteins (LBPs) superfamily, regulating the fatty acid uptake and intercellular transport. Among 9 subtypes identified with tissue-specific distribution, serum A- and H-FABP have been found to be significantly higher in patients with obstructive sleep apnea (OSA) than in controls (Sleep Breath 2008;12:223-228; Eur Respir J 2009;33:346-351). Intermittent hypoxia (IH) is a hallmark feature in OSA, which is increasingly recognized as an independent risk factor of cardiovascular diseases (CVD). In this study, we hypothesized that IH could regulate both lipid parameters and the expression of specific ABPs leading to heart damage. We aimed to study systemic and cardiac lipid parameters and the specific expression of cardiac FABPs. METHODS: Male Sprague–Dawley rats …-
dc.languageengen_US
dc.publisherAmerican Thoracic Society. The Journal's web site is located at http://ajrccm.atsjournals.org-
dc.relation.ispartofAmerican Journal of Respiratory and Critical Care Medicineen_US
dc.subjectMedical sciences-
dc.subjectRespiratory diseases-
dc.titleEffects of intermittent hypoxia on the expression levels of fatty acid-binding protein in rat hearten_US
dc.typeConference_Paperen_US
dc.identifier.emailMak, JCW: judymak@hku.hken_US
dc.identifier.emailYeung, SC: flag@hkucc.hku.hken_US
dc.identifier.emailIp, MSM: msmip@hku.hken_US
dc.identifier.authorityMak, JCW=rp00352en_US
dc.identifier.authorityIp, MSM=rp00347en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1164/ajrccm-conference.2012.185.1_MeetingAbstracts.A3869-
dc.identifier.hkuros204434en_US
dc.identifier.volume185en_US
dc.identifier.issuemeeting abstracts-
dc.publisher.placeUnited States-
dc.customcontrol.immutablesml 140123-

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