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Article: Chinese herbal medicine for insomnia: A systematic review of randomized controlled trials

TitleChinese herbal medicine for insomnia: A systematic review of randomized controlled trials
Authors
KeywordsChinese herbal medicine
Insomnia
Meta-analysis
Randomized controlled trial
Systematic review
Traditional Chinese medicine
Issue Date2012
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/smrv
Citation
Sleep Medicine Reviews, 2012, v. 16 n. 6, p. 497-507 How to Cite?
AbstractChinese herbal medicine (CHM), either in single herb or in herbal formula, has been used to treat insomnia for more than 2000 years. A systematic review including Chinese and English literature of randomized controlled trials was conducted to examine the efficacy, safety, and composition of CHM for insomnia. Among the 217 studies we have reviewed, only eight had a Jadad score ≥3, and seven out of these eight studies had at least one domain with high risks of bias. Meta-analyses of the studies with Jadad score ≥3 found that CHM was similar to Western medication (three studies) and placebo (three studies) in treating insomnia. Due to the poor methodological quality of the studies and the small number of trials included in meta-analyses, the current evidence is insufficient to support the efficacy of CHM for insomnia. The frequency of adverse events associated with CHM was similar to that of placebo, but lower than with Western medication. Gui Pi Tang was the most commonly used standardized formula, while Suan Zao Ren (Ziziphus jujuba) was the most frequently used single herb. Further studies with a double-blind placebo-controlled design are needed to accurately determine the benefits and risks of CHM for insomnia. © 2012 Elsevier Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/159817
ISSN
2015 Impact Factor: 7.341
2015 SCImago Journal Rankings: 3.285
References

 

DC FieldValueLanguage
dc.contributor.authorYeung, WFen_HK
dc.contributor.authorChung, KFen_HK
dc.contributor.authorPoon, MMKen_HK
dc.contributor.authorHo, FYYen_HK
dc.contributor.authorZhang, SPen_HK
dc.contributor.authorZhang, ZJen_HK
dc.contributor.authorZiea, ETCen_HK
dc.contributor.authorWong, VTen_HK
dc.date.accessioned2012-08-16T05:57:36Z-
dc.date.available2012-08-16T05:57:36Z-
dc.date.issued2012en_HK
dc.identifier.citationSleep Medicine Reviews, 2012, v. 16 n. 6, p. 497-507en_HK
dc.identifier.issn1087-0792en_HK
dc.identifier.urihttp://hdl.handle.net/10722/159817-
dc.description.abstractChinese herbal medicine (CHM), either in single herb or in herbal formula, has been used to treat insomnia for more than 2000 years. A systematic review including Chinese and English literature of randomized controlled trials was conducted to examine the efficacy, safety, and composition of CHM for insomnia. Among the 217 studies we have reviewed, only eight had a Jadad score ≥3, and seven out of these eight studies had at least one domain with high risks of bias. Meta-analyses of the studies with Jadad score ≥3 found that CHM was similar to Western medication (three studies) and placebo (three studies) in treating insomnia. Due to the poor methodological quality of the studies and the small number of trials included in meta-analyses, the current evidence is insufficient to support the efficacy of CHM for insomnia. The frequency of adverse events associated with CHM was similar to that of placebo, but lower than with Western medication. Gui Pi Tang was the most commonly used standardized formula, while Suan Zao Ren (Ziziphus jujuba) was the most frequently used single herb. Further studies with a double-blind placebo-controlled design are needed to accurately determine the benefits and risks of CHM for insomnia. © 2012 Elsevier Ltd.en_HK
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/smrven_HK
dc.relation.ispartofSleep Medicine Reviewsen_HK
dc.subjectChinese herbal medicineen_HK
dc.subjectInsomniaen_HK
dc.subjectMeta-analysisen_HK
dc.subjectRandomized controlled trialen_HK
dc.subjectSystematic reviewen_HK
dc.subjectTraditional Chinese medicineen_HK
dc.titleChinese herbal medicine for insomnia: A systematic review of randomized controlled trialsen_HK
dc.typeArticleen_HK
dc.identifier.emailChung, KF: kfchung@hkucc.hku.hken_HK
dc.identifier.emailZhang, ZJ: zhangzj@hkucc.hku.hken_HK
dc.identifier.authorityChung, KF=rp00377en_HK
dc.identifier.authorityZhang, ZJ=rp01297en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.smrv.2011.12.005en_HK
dc.identifier.pmid22440393-
dc.identifier.scopuseid_2-s2.0-84867196157en_HK
dc.identifier.hkuros203552en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84867196157&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue6en_HK
dc.identifier.spage497en_HK
dc.identifier.epage507en_HK
dc.identifier.eissn1532-2955-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYeung, WF=24345897100en_HK
dc.identifier.scopusauthoridChung, KF=7404086681en_HK
dc.identifier.scopusauthoridManKi Poon, M=55097092500en_HK
dc.identifier.scopusauthoridYanYee Ho, F=55097092600en_HK
dc.identifier.scopusauthoridZhang, SP=55098192200en_HK
dc.identifier.scopusauthoridZhang, ZJ=8061473900en_HK
dc.identifier.scopusauthoridTatChi Ziea, E=55097092300en_HK
dc.identifier.scopusauthoridWong, VT=16176799600en_HK
dc.customcontrol.immutablejt 130515-

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