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Article: Preparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNA
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TitlePreparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNA
 
AuthorsLi, X3
Liu, G3
Yan, W3
Chu, PK2
Yeung, KWK1
Wu, S3 2 1
Yi, C3 2 1
Xu, Z3 2 1
 
KeywordsDNA
Emulsifier-free emulsion polymerization
Fluorescence spectroscopy
Magnetic polymer
Polycations
 
Issue Date2012
 
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jmmm
 
CitationJournal Of Magnetism And Magnetic Materials, 2012, v. 324 n. 7, p. 1410-1418 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jmmm.2011.11.056
 
AbstractCationic magnetic polymer particles Fe 3O 4/ poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride), a type of potential gene carrier, were prepared by emulsifier-free emulsion polymerization with oleic acid modified magnetite Fe 3O 4, styrene, butyl acrylate and [2-(methacryloxy)ethyl]trimethylammonium chloride) (METAC). The morphology of the particles was characterized by transmission electron microscopy and the composites of particles were characterized by FT-IR spectroscopy, X-ray diffraction. These results showed that magnetic particles were well dispersed in polymers with the content of about 15%(wt/wt). The composites exhibited superparamagnetism and possessed a certain level of magnetic response. The interactions between the particles with calf-thymus DNA (ct DNA) were confirmed by zeta potential measurement, UVvis spectroscopy and fluorescence spectroscopy. The DNA-binding capacity determined by the agarose gel electrophoresis showed good binding capacity of the emulsion to DNA. These results suggested the potential of the cationic magnetic polymer emulsion as gene target delivery carrier. © 2011 Elsevier B.V. All rights reserved.
 
ISSN0304-8853
2013 Impact Factor: 2.002
2013 SCImago Journal Rankings: 0.935
 
DOIhttp://dx.doi.org/10.1016/j.jmmm.2011.11.056
 
ISI Accession Number IDWOS:000299010100026
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLi, X
 
dc.contributor.authorLiu, G
 
dc.contributor.authorYan, W
 
dc.contributor.authorChu, PK
 
dc.contributor.authorYeung, KWK
 
dc.contributor.authorWu, S
 
dc.contributor.authorYi, C
 
dc.contributor.authorXu, Z
 
dc.date.accessioned2012-08-16T05:55:35Z
 
dc.date.available2012-08-16T05:55:35Z
 
dc.date.issued2012
 
dc.description.abstractCationic magnetic polymer particles Fe 3O 4/ poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride), a type of potential gene carrier, were prepared by emulsifier-free emulsion polymerization with oleic acid modified magnetite Fe 3O 4, styrene, butyl acrylate and [2-(methacryloxy)ethyl]trimethylammonium chloride) (METAC). The morphology of the particles was characterized by transmission electron microscopy and the composites of particles were characterized by FT-IR spectroscopy, X-ray diffraction. These results showed that magnetic particles were well dispersed in polymers with the content of about 15%(wt/wt). The composites exhibited superparamagnetism and possessed a certain level of magnetic response. The interactions between the particles with calf-thymus DNA (ct DNA) were confirmed by zeta potential measurement, UVvis spectroscopy and fluorescence spectroscopy. The DNA-binding capacity determined by the agarose gel electrophoresis showed good binding capacity of the emulsion to DNA. These results suggested the potential of the cationic magnetic polymer emulsion as gene target delivery carrier. © 2011 Elsevier B.V. All rights reserved.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Magnetism And Magnetic Materials, 2012, v. 324 n. 7, p. 1410-1418 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.jmmm.2011.11.056
 
dc.identifier.citeulike10135398
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.jmmm.2011.11.056
 
dc.identifier.epage1418
 
dc.identifier.hkuros204535
 
dc.identifier.isiWOS:000299010100026
 
dc.identifier.issn0304-8853
2013 Impact Factor: 2.002
2013 SCImago Journal Rankings: 0.935
 
dc.identifier.issue7
 
dc.identifier.scopuseid_2-s2.0-84855440269
 
dc.identifier.spage1410
 
dc.identifier.urihttp://hdl.handle.net/10722/159756
 
dc.identifier.volume324
 
dc.languageeng
 
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jmmm
 
dc.publisher.placeNetherlands
 
dc.relation.ispartofJournal of Magnetism and Magnetic Materials
 
dc.relation.referencesReferences in Scopus
 
dc.subjectDNA
 
dc.subjectEmulsifier-free emulsion polymerization
 
dc.subjectFluorescence spectroscopy
 
dc.subjectMagnetic polymer
 
dc.subjectPolycations
 
dc.titlePreparation of Fe 3O 4/poly(styrene-butyl acrylate-[2-(methacryloxy)ethyl]trimethylammonium chloride) by emulsifier-free emulsion polymerization and its interaction with DNA
 
dc.typeArticle
 
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<contributor.author>Yeung, KWK</contributor.author>
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Author Affiliations
  1. The University of Hong Kong
  2. City University of Hong Kong
  3. Hubei University