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Article: Hepatitis B virus X gene in the development of hepatocellular carcinoma

TitleHepatitis B virus X gene in the development of hepatocellular carcinoma
Authors
Issue Date2011
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk
Citation
Hong Kong Medical Journal, 2011, v. 17 n. 6, suppl. 6, p. 44-47 How to Cite?
AbstractKey Messages 1. Deletion of the 3’end of the hepatitis B virus X gene (HBx) was frequently detected in clinical hepatocellular carcinoma (HCC) samples. 2. In vivo animal tumour xenograft experiments demonstrated the tumourigenic ability of the C-terminal truncated HBx. 3. cDNA microarray study suggested that the C-terminal truncated HBx played a critical role in the HCC development via activation of cell proliferation and inhibition of apoptosis.
Persistent Identifierhttp://hdl.handle.net/10722/159463
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorMa, NFen_US
dc.contributor.authorLau, SHen_US
dc.contributor.authorHu, Len_US
dc.contributor.authorDong, SSen_US
dc.contributor.authorGuan, XYen_US
dc.date.accessioned2012-08-16T05:50:18Z-
dc.date.available2012-08-16T05:50:18Z-
dc.date.issued2011en_US
dc.identifier.citationHong Kong Medical Journal, 2011, v. 17 n. 6, suppl. 6, p. 44-47en_US
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/159463-
dc.description.abstractKey Messages 1. Deletion of the 3’end of the hepatitis B virus X gene (HBx) was frequently detected in clinical hepatocellular carcinoma (HCC) samples. 2. In vivo animal tumour xenograft experiments demonstrated the tumourigenic ability of the C-terminal truncated HBx. 3. cDNA microarray study suggested that the C-terminal truncated HBx played a critical role in the HCC development via activation of cell proliferation and inhibition of apoptosis.-
dc.languageengen_US
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org.hk-
dc.relation.ispartofHong Kong Medical Journalen_US
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject.meshCarcinoma, Hepatocellular - virology-
dc.subject.meshHepatitis B - complications - virology-
dc.subject.meshLiver Neoplasms, Experimental - virology-
dc.subject.meshTrans-Activators - genetics-
dc.subject.meshXenograft Model Antitumor Assays-
dc.titleHepatitis B virus X gene in the development of hepatocellular carcinomaen_US
dc.typeArticleen_US
dc.identifier.emailHu, L: lhuc@hkusua.hku.hken_US
dc.identifier.emailDong, SS: dongss@hku.hken_US
dc.identifier.emailGuan, XY: xyguan@hkucc.hku.hken_US
dc.identifier.authorityGuan, X=rp00454en_US
dc.description.naturepublished_or_final_version-
dc.identifier.pmid22147360-
dc.identifier.scopuseid_2-s2.0-84859715833-
dc.identifier.hkuros203474en_US
dc.identifier.volume17en_US
dc.identifier.issue6, suppl. 6-
dc.identifier.spage44en_US
dc.identifier.epage47en_US
dc.publisher.placeHong Kong-

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