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Article: Alternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids
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TitleAlternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids
 
AuthorsLi, C
Zheng, L
 
KeywordsLichen planus, oral
Steroids
Tacrolimus
 
Issue Date2012
 
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkda.org/hkdj/
 
CitationHong Kong Dental Journal, 2012, v. 9 n. 1, p. 39-42 [How to Cite?]
 
AbstractLichen planus is a T-cell–mediated immunological disorder causing inflammatory lesions on the skin and oral mucosa. The etiology of lichen planus remains unknown, and the current therapeutic strategy is primarily to manage the symptoms. Although topical steroids are commonly used in the treatment of lichen planus, there are lesions refractory to steroids that require different treatment options. This report is of a patient with bilateral erosive oral lichen planus of the buccal mucosa. The lesions did not respond to highpotency topical steroids, so they were treated with topical tacrolimus 0.1% ointment, a potent topical immunosuppressant. All the erosive lesions healed, and the associated pain and bleeding disappeared after 6 weeks of treatment.
 
DescriptionCase reports
 
ISSN1727-2300
 
DC FieldValue
dc.contributor.authorLi, C
 
dc.contributor.authorZheng, L
 
dc.date.accessioned2012-08-16T05:46:51Z
 
dc.date.available2012-08-16T05:46:51Z
 
dc.date.issued2012
 
dc.description.abstractLichen planus is a T-cell–mediated immunological disorder causing inflammatory lesions on the skin and oral mucosa. The etiology of lichen planus remains unknown, and the current therapeutic strategy is primarily to manage the symptoms. Although topical steroids are commonly used in the treatment of lichen planus, there are lesions refractory to steroids that require different treatment options. This report is of a patient with bilateral erosive oral lichen planus of the buccal mucosa. The lesions did not respond to highpotency topical steroids, so they were treated with topical tacrolimus 0.1% ointment, a potent topical immunosuppressant. All the erosive lesions healed, and the associated pain and bleeding disappeared after 6 weeks of treatment.
 
dc.description.naturepublished_or_final_version
 
dc.descriptionCase reports
 
dc.identifier.citationHong Kong Dental Journal, 2012, v. 9 n. 1, p. 39-42 [How to Cite?]
 
dc.identifier.epage42
 
dc.identifier.hkuros204630
 
dc.identifier.issn1727-2300
 
dc.identifier.issue1
 
dc.identifier.spage39
 
dc.identifier.urihttp://hdl.handle.net/10722/159231
 
dc.identifier.volume9
 
dc.languageeng
 
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkda.org/hkdj/
 
dc.publisher.placeHong Kong
 
dc.relation.ispartofHong Kong Dental Journal
 
dc.rightsHong Kong Dental Journal. Copyright © Hong Kong Academy of Medicine Press.
 
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
 
dc.subjectLichen planus, oral
 
dc.subjectSteroids
 
dc.subjectTacrolimus
 
dc.titleAlternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids
 
dc.typeArticle
 
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<contributor.author>Zheng, L</contributor.author>
<date.accessioned>2012-08-16T05:46:51Z</date.accessioned>
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<description>Case reports</description>
<description.abstract>Lichen planus is a T-cell&#8211;mediated immunological disorder causing inflammatory lesions
on the skin and oral mucosa. The etiology of lichen planus remains unknown, and the
current therapeutic strategy is primarily to manage the symptoms. Although topical
steroids are commonly used in the treatment of lichen planus, there are lesions refractory
to steroids that require different treatment options. This report is of a patient with bilateral
erosive oral lichen planus of the buccal mucosa. The lesions did not respond to highpotency
topical steroids, so they were treated with topical tacrolimus 0.1% ointment, a
potent topical immunosuppressant. All the erosive lesions healed, and the associated
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<subject>Lichen planus, oral</subject>
<subject>Steroids</subject>
<subject>Tacrolimus</subject>
<title>Alternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids</title>
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