Article: Alternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids

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TitleAlternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids
AuthorsLi, C
Zheng, L
KeywordsLichen planus, oral
Steroids
Tacrolimus
Issue Date2012
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkda.org/hkdj/
CitationHong Kong Dental Journal, 2012, v. 9 n. 1, p. 39-42 [How to Cite?]
AbstractLichen planus is a T-cell–mediated immunological disorder causing inflammatory lesions on the skin and oral mucosa. The etiology of lichen planus remains unknown, and the current therapeutic strategy is primarily to manage the symptoms. Although topical steroids are commonly used in the treatment of lichen planus, there are lesions refractory to steroids that require different treatment options. This report is of a patient with bilateral erosive oral lichen planus of the buccal mucosa. The lesions did not respond to highpotency topical steroids, so they were treated with topical tacrolimus 0.1% ointment, a potent topical immunosuppressant. All the erosive lesions healed, and the associated pain and bleeding disappeared after 6 weeks of treatment.
DescriptionCase reports
ISSN1727-2300
DC Field
Value
dc.contributor.authorLi, C
dc.contributor.authorZheng, L
dc.date.accessioned2012-08-16T05:46:51Z
dc.date.available2012-08-16T05:46:51Z
dc.date.issued2012
dc.description.abstractLichen planus is a T-cell–mediated immunological disorder causing inflammatory lesions on the skin and oral mucosa. The etiology of lichen planus remains unknown, and the current therapeutic strategy is primarily to manage the symptoms. Although topical steroids are commonly used in the treatment of lichen planus, there are lesions refractory to steroids that require different treatment options. This report is of a patient with bilateral erosive oral lichen planus of the buccal mucosa. The lesions did not respond to highpotency topical steroids, so they were treated with topical tacrolimus 0.1% ointment, a potent topical immunosuppressant. All the erosive lesions healed, and the associated pain and bleeding disappeared after 6 weeks of treatment.
dc.description.naturepublished_or_final_version
dc.descriptionCase reports
dc.identifier.citationHong Kong Dental Journal, 2012, v. 9 n. 1, p. 39-42 [How to Cite?]
dc.identifier.epage42
dc.identifier.hkuros204630
dc.identifier.issn1727-2300
dc.identifier.issue1
dc.identifier.spage39
dc.identifier.urihttp://hdl.handle.net/10722/159231
dc.identifier.volume9
dc.languageeng
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkda.org/hkdj/
dc.publisher.placeHong Kong
dc.relation.ispartofHong Kong Dental Journal
dc.rightsHong Kong Dental Journal. Copyright © Hong Kong Academy of Medicine Press.
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License
dc.subjectLichen planus, oral
dc.subjectSteroids
dc.subjectTacrolimus
dc.titleAlternative treatment using topical tacrolimus for erosive oral lichen planus resistant to steroids
dc.typeArticle