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Article: The role of vascular endothelial growth factor in ossification
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TitleThe role of vascular endothelial growth factor in ossification
 
AuthorsYang, Y1
Tan, YY1 2
Wong, RWK1
Wenden, A1
Zhang, LK1 3
Rabie, ABM3
 
Issue Date2012
 
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ijos/index.html
 
CitationInternational Journal of Oral Science, 2012, v. 4, p. 64-68 [How to Cite?]
DOI: http://dx.doi.org/10.1038/ijos.2012.33
 
AbstractOsteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development.
 
ISSN1674-2818
2013 Impact Factor: 2.029
2013 SCImago Journal Rankings: 0.695
 
DOIhttp://dx.doi.org/10.1038/ijos.2012.33
 
PubMed Central IDPMC3412670
 
ISI Accession Number IDWOS:000306502600002
 
DC FieldValue
dc.contributor.authorYang, Y
 
dc.contributor.authorTan, YY
 
dc.contributor.authorWong, RWK
 
dc.contributor.authorWenden, A
 
dc.contributor.authorZhang, LK
 
dc.contributor.authorRabie, ABM
 
dc.date.accessioned2012-08-16T05:46:45Z
 
dc.date.available2012-08-16T05:46:45Z
 
dc.date.issued2012
 
dc.description.abstractOsteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationInternational Journal of Oral Science, 2012, v. 4, p. 64-68 [How to Cite?]
DOI: http://dx.doi.org/10.1038/ijos.2012.33
 
dc.identifier.doihttp://dx.doi.org/10.1038/ijos.2012.33
 
dc.identifier.epage68
 
dc.identifier.hkuros202159
 
dc.identifier.isiWOS:000306502600002
 
dc.identifier.issn1674-2818
2013 Impact Factor: 2.029
2013 SCImago Journal Rankings: 0.695
 
dc.identifier.pmcidPMC3412670
 
dc.identifier.pmid22722639
 
dc.identifier.scopuseid_2-s2.0-84864260041
 
dc.identifier.spage64
 
dc.identifier.urihttp://hdl.handle.net/10722/159211
 
dc.identifier.volume4
 
dc.languageeng
 
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ijos/index.html
 
dc.publisher.placeChina
 
dc.relation.ispartofInternational Journal of Oral Science
 
dc.subject.meshCalcification, Physiologic - physiology
 
dc.subject.meshNeovascularization, Physiologic - physiology
 
dc.subject.meshOsteoclasts - physiology
 
dc.subject.meshOsteogenesis - physiology
 
dc.subject.meshVascular Endothelial Growth Factor A - physiology
 
dc.titleThe role of vascular endothelial growth factor in ossification
 
dc.typeArticle
 
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<contributor.author>Tan, YY</contributor.author>
<contributor.author>Wong, RWK</contributor.author>
<contributor.author>Wenden, A</contributor.author>
<contributor.author>Zhang, LK</contributor.author>
<contributor.author>Rabie, ABM</contributor.author>
<date.accessioned>2012-08-16T05:46:45Z</date.accessioned>
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Author Affiliations
  1. The University of Hong Kong
  2. Klinik Pergigian
  3. Nankai University