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Article: The role of vascular endothelial growth factor in ossification

TitleThe role of vascular endothelial growth factor in ossification
Authors
Yang, YTan, YYWong, RWKWenden, AZhang, LKRabie, ABM
Keywordsendochondral ossification
intramembranous ossification
osteogenesis
vascular endothelial growth factor
Issue Date2012
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ijos/index.html
Citation
International Journal of Oral Science, 2012, v. 4, p. 64-68 How to Cite?
DOI: http://dx.doi.org/10.1038/ijos.2012.33
AbstractOsteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development.
Persistent Identifierhttp://hdl.handle.net/10722/159211
ISSN
1674-2818
2023 Impact Factor: 10.8
2023 SCImago Journal Rankings: 2.596
PubMed Central ID
PMC3412670
ISI Accession Number ID
WOS:000306502600002

 

DC FieldValueLanguage
dc.contributor.authorYang, Yen_US
dc.contributor.authorTan, YYen_US
dc.contributor.authorWong, RWKen_US
dc.contributor.authorWenden, Aen_US
dc.contributor.authorZhang, LKen_US
dc.contributor.authorRabie, ABMen_US
dc.date.accessioned2012-08-16T05:46:45Z-
dc.date.available2012-08-16T05:46:45Z-
dc.date.issued2012en_US
dc.identifier.citationInternational Journal of Oral Science, 2012, v. 4, p. 64-68en_US
dc.identifier.issn1674-2818-
dc.identifier.urihttp://hdl.handle.net/10722/159211-
dc.description.abstractOsteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair.Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development.-
dc.languageengen_US
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ijos/index.html-
dc.relation.ispartofInternational Journal of Oral Scienceen_US
dc.subjectendochondral ossification-
dc.subjectintramembranous ossification-
dc.subjectosteogenesis-
dc.subjectvascular endothelial growth factor-
dc.subject.meshCalcification, Physiologic - physiology-
dc.subject.meshNeovascularization, Physiologic - physiology-
dc.subject.meshOsteoclasts - physiology-
dc.subject.meshOsteogenesis - physiology-
dc.subject.meshVascular Endothelial Growth Factor A - physiology-
dc.titleThe role of vascular endothelial growth factor in ossificationen_US
dc.typeArticleen_US
dc.identifier.emailYang, Y: yangyanq@hkucc.hku.hken_US
dc.identifier.emailWong, RWK: fyoung@hku.hken_US
dc.identifier.emailRabie, ABM: rabie@hku.hken_US
dc.identifier.authorityYang, Y=rp00045en_US
dc.identifier.authorityWong, RWK=rp00038en_US
dc.identifier.authorityRabie, ABM=rp00029en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1038/ijos.2012.33-
dc.identifier.pmid22722639-
dc.identifier.pmcidPMC3412670-
dc.identifier.scopuseid_2-s2.0-84864260041-
dc.identifier.hkuros202159en_US
dc.identifier.volume4en_US
dc.identifier.spage64en_US
dc.identifier.epage68en_US
dc.identifier.isiWOS:000306502600002-
dc.publisher.placeChina-
dc.identifier.issnl1674-2818-

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