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Conference Paper: Manufacture and evaluation of bioactive and biodegradable materials and scaffolds for tissue engineering

TitleManufacture and evaluation of bioactive and biodegradable materials and scaffolds for tissue engineering
Authors
Issue Date2001
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0957-4530
Citation
Journal Of Materials Science: Materials In Medicine, 2001, v. 12 n. 10-12, p. 855-860 How to Cite?
AbstractFor tissue regeneration and tissue engineering applications, a number of bioactive and biodegradable composites, either porous or non-porous, were fabricated. The newly developed materials included tricalcium phosphate reinforced polyhydroxybutyrate and its copolymer, poorly crystallized hydroxyapatite reinforced chitin, and plasma sprayed hydroxyapatite reinforced poly(L-lactic acid). It was shown that these new materials could be successfully produced using the manufacturing techniques adopted. In vitro experiments revealed that the incorporation of bioceramic particles in biodegradable polymers rendered the composites bioactive and significantly improved the ability of composites to induce the formation of bone-like apatite on their surfaces. Degradation of composite scaffolds in simulated body fluid was observed and could be due to the simultaneous degradation of polymer matrix and dissolution of bioceramic particles. © 2001 Kluwer Academic Publishers.
Persistent Identifierhttp://hdl.handle.net/10722/158931
ISSN
2015 Impact Factor: 2.272
2013 SCImago Journal Rankings: 0.897
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWang, Men_US
dc.contributor.authorChen, LJen_US
dc.contributor.authorNi, Jen_US
dc.contributor.authorWeng, Jen_US
dc.contributor.authorYue, CYen_US
dc.date.accessioned2012-08-08T09:04:38Z-
dc.date.available2012-08-08T09:04:38Z-
dc.date.issued2001en_US
dc.identifier.citationJournal Of Materials Science: Materials In Medicine, 2001, v. 12 n. 10-12, p. 855-860en_US
dc.identifier.issn0957-4530en_US
dc.identifier.urihttp://hdl.handle.net/10722/158931-
dc.description.abstractFor tissue regeneration and tissue engineering applications, a number of bioactive and biodegradable composites, either porous or non-porous, were fabricated. The newly developed materials included tricalcium phosphate reinforced polyhydroxybutyrate and its copolymer, poorly crystallized hydroxyapatite reinforced chitin, and plasma sprayed hydroxyapatite reinforced poly(L-lactic acid). It was shown that these new materials could be successfully produced using the manufacturing techniques adopted. In vitro experiments revealed that the incorporation of bioceramic particles in biodegradable polymers rendered the composites bioactive and significantly improved the ability of composites to induce the formation of bone-like apatite on their surfaces. Degradation of composite scaffolds in simulated body fluid was observed and could be due to the simultaneous degradation of polymer matrix and dissolution of bioceramic particles. © 2001 Kluwer Academic Publishers.en_US
dc.languageengen_US
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0957-4530en_US
dc.relation.ispartofJournal of Materials Science: Materials in Medicineen_US
dc.titleManufacture and evaluation of bioactive and biodegradable materials and scaffolds for tissue engineeringen_US
dc.typeConference_Paperen_US
dc.identifier.emailWang, M:memwang@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1023/A:1012899318688en_US
dc.identifier.scopuseid_2-s2.0-0035681702en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035681702&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue10-12en_US
dc.identifier.spage855en_US
dc.identifier.epage860en_US
dc.identifier.isiWOS:000172280300003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWang, M=15749714100en_US
dc.identifier.scopusauthoridChen, LJ=7409439036en_US
dc.identifier.scopusauthoridNi, J=8859102900en_US
dc.identifier.scopusauthoridWeng, J=7202292060en_US
dc.identifier.scopusauthoridYue, CY=7102350337en_US

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