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Article: Isolation and characterization of antimicrobial, anti-inflammatory and chemopreventive flavones from premna odorata blanco

TitleIsolation and characterization of antimicrobial, anti-inflammatory and chemopreventive flavones from premna odorata blanco
Authors
Keywords'Alagau'
'Pito-pito'
Acacetin
Anti-inflammatory
Antimicrobial
Chemopreventive
Diosmetin
Flavones
Premna odorata Blanco (Verbenaceae)
Issue Date2011
PublisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/jmpr
Citation
Journal Of Medicinal Plants Research, 2011, v. 5 n. 13, p. 2729-2735 How to Cite?
AbstractPremna odorata Blanco (Verbenaceae) is a native tree of the Philippines where its leaves are used traditionally for vaginal irrigation and tuberculosis. It is one of the seven components of a commercialized Philippine herbal preparation called "Pito-Pito". Its medicinal uses, however, have not been scientifically validated. This tree is not commonly cultivated and thrive in the less accessible limestone forests of the Philippines. Solvent partitioning and fractionation of the ethanolic crude extract of the leaves isolated two yellow amorphous powders. The identities of these compounds were determined by LC/MS/MS and NMR spectroscopic analyses, and their spectra were compared with literature data. The isolates were flavone aglycones which were the widespread acacetin and the nonwidespread diosmetin. These flavones were isolated from the P. odorata for the first time ever. They had been reported by earlier studies to exhibit medicinal properties as antimicrobial, anti-inflammatory and chemopreventive. Thus, the current study has provided a scientific evidence of the medicinal properties of the leaves of P. odorata that could become the popular basis for the plant's sustainable use, conservation and cultivation. © 2011 Academic Journals.
Persistent Identifierhttp://hdl.handle.net/10722/157638
ISSN
2010 Impact Factor: 0.879
2014 SCImago Journal Rankings: 0.407
References

 

DC FieldValueLanguage
dc.contributor.authorPinzon, LCen_HK
dc.contributor.authorUy, MMen_HK
dc.contributor.authorSze, KHen_HK
dc.contributor.authorWang, Men_HK
dc.contributor.authorChu, IKen_HK
dc.date.accessioned2012-08-08T08:51:52Z-
dc.date.available2012-08-08T08:51:52Z-
dc.date.issued2011en_HK
dc.identifier.citationJournal Of Medicinal Plants Research, 2011, v. 5 n. 13, p. 2729-2735en_HK
dc.identifier.issn1996-0875en_HK
dc.identifier.urihttp://hdl.handle.net/10722/157638-
dc.description.abstractPremna odorata Blanco (Verbenaceae) is a native tree of the Philippines where its leaves are used traditionally for vaginal irrigation and tuberculosis. It is one of the seven components of a commercialized Philippine herbal preparation called "Pito-Pito". Its medicinal uses, however, have not been scientifically validated. This tree is not commonly cultivated and thrive in the less accessible limestone forests of the Philippines. Solvent partitioning and fractionation of the ethanolic crude extract of the leaves isolated two yellow amorphous powders. The identities of these compounds were determined by LC/MS/MS and NMR spectroscopic analyses, and their spectra were compared with literature data. The isolates were flavone aglycones which were the widespread acacetin and the nonwidespread diosmetin. These flavones were isolated from the P. odorata for the first time ever. They had been reported by earlier studies to exhibit medicinal properties as antimicrobial, anti-inflammatory and chemopreventive. Thus, the current study has provided a scientific evidence of the medicinal properties of the leaves of P. odorata that could become the popular basis for the plant's sustainable use, conservation and cultivation. © 2011 Academic Journals.en_HK
dc.languageengen_US
dc.publisherAcademic Journals. The Journal's web site is located at http://www.academicjournals.org/jmpren_HK
dc.relation.ispartofJournal of Medicinal Plants Researchen_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subject'Alagau'en_HK
dc.subject'Pito-pito'en_HK
dc.subjectAcacetinen_HK
dc.subjectAnti-inflammatoryen_HK
dc.subjectAntimicrobialen_HK
dc.subjectChemopreventiveen_HK
dc.subjectDiosmetinen_HK
dc.subjectFlavonesen_HK
dc.subjectPremna odorata Blanco (Verbenaceae)en_HK
dc.titleIsolation and characterization of antimicrobial, anti-inflammatory and chemopreventive flavones from premna odorata blancoen_HK
dc.typeArticleen_HK
dc.identifier.emailSze, KH: khsze@hku.hken_HK
dc.identifier.emailWang, M: mfwang@hku.hken_HK
dc.identifier.emailChu, IK: ivankchu@hku.hken_HK
dc.identifier.authoritySze, KH=rp00785en_HK
dc.identifier.authorityWang, M=rp00800en_HK
dc.identifier.authorityChu, IK=rp00683en_HK
dc.description.naturepublished_or_final_versionen_US
dc.identifier.scopuseid_2-s2.0-79961033416en_HK
dc.identifier.hkuros211421-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79961033416&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue13en_HK
dc.identifier.spage2729en_HK
dc.identifier.epage2735en_HK
dc.publisher.placeNigeriaen_HK
dc.identifier.scopusauthoridPinzon, LC=45561575300en_HK
dc.identifier.scopusauthoridUy, MM=12244584200en_HK
dc.identifier.scopusauthoridSze, KH=7006735061en_HK
dc.identifier.scopusauthoridWang, M=7406691844en_HK
dc.identifier.scopusauthoridChu, IK=7103327484en_HK

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