File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Antimicrobial resistance in Escherichia coli outpatient urinary isolates from women: emerging multidrug resistance phenotypes

TitleAntimicrobial resistance in Escherichia coli outpatient urinary isolates from women: emerging multidrug resistance phenotypes
Authors
Issue Date2007
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/diagmicrobio
Citation
Diagnostic Microbiology And Infectious Disease, 2007, v. 59 n. 4, p. 439-445 How to Cite?
Abstract
This study evaluated the antimicrobial resistance profile of outpatient urinary Escherichia coli isolated from women obtained throughout Hong Kong during 2004-2005. Of 1067 single patient isolates analyzed, 60.1% were resistant to ampicillin, 34% were resistant to co-trimoxazole, and 22.1% were resistant to ciprofloxacin. Thirty-four (6.6%) of 519 isolates in 2004 and 55 (10%) of 548 isolates in 2005 were extended-spectrum β-lactamase (ESBL) producers with a CTX-M phenotype. Rates of non-β-lactam resistance and ESBL production were strongly influenced by patient age. The age-stratified rates for dual co-trimoxazole and ciprofloxacin resistance and for ESBL production were 10.9% and 7.6% in women aged 18-35 years, 13% and 6.9% in women aged 36-50 years, 20.4% and 8.8% in women aged 51-64 years, and 23.7% and 11.8% in women aged ≥65 years, respectively. Nitrofurantoin and fosfomycin remain active against >90% of the isolates, irrespective of the resistance phenotypes for other drugs. Our results documented the emergence of problematic resistance phenotypes among community urinary E. coli and highlight the need to explore strategies for their containment. © 2007 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/157496
ISSN
2013 Impact Factor: 2.568
2013 SCImago Journal Rankings: 1.275
ISI Accession Number ID
References

 

Author Affiliations
  1. Tuen Mun Hospital
  2. St. Teresa's Hospital
  3. null
  4. Centre of Infection
DC FieldValueLanguage
dc.contributor.authorHo, PLen_US
dc.contributor.authorWong, RCWen_US
dc.contributor.authorYip, KSen_US
dc.contributor.authorLoke, SLen_US
dc.contributor.authorLeung, MSTen_US
dc.contributor.authorMak, GCen_US
dc.contributor.authorChow, FKHen_US
dc.contributor.authorTsang, KWTen_US
dc.contributor.authorQue, TLen_US
dc.date.accessioned2012-08-08T08:50:34Z-
dc.date.available2012-08-08T08:50:34Z-
dc.date.issued2007en_US
dc.identifier.citationDiagnostic Microbiology And Infectious Disease, 2007, v. 59 n. 4, p. 439-445en_US
dc.identifier.issn0732-8893en_US
dc.identifier.urihttp://hdl.handle.net/10722/157496-
dc.description.abstractThis study evaluated the antimicrobial resistance profile of outpatient urinary Escherichia coli isolated from women obtained throughout Hong Kong during 2004-2005. Of 1067 single patient isolates analyzed, 60.1% were resistant to ampicillin, 34% were resistant to co-trimoxazole, and 22.1% were resistant to ciprofloxacin. Thirty-four (6.6%) of 519 isolates in 2004 and 55 (10%) of 548 isolates in 2005 were extended-spectrum β-lactamase (ESBL) producers with a CTX-M phenotype. Rates of non-β-lactam resistance and ESBL production were strongly influenced by patient age. The age-stratified rates for dual co-trimoxazole and ciprofloxacin resistance and for ESBL production were 10.9% and 7.6% in women aged 18-35 years, 13% and 6.9% in women aged 36-50 years, 20.4% and 8.8% in women aged 51-64 years, and 23.7% and 11.8% in women aged ≥65 years, respectively. Nitrofurantoin and fosfomycin remain active against >90% of the isolates, irrespective of the resistance phenotypes for other drugs. Our results documented the emergence of problematic resistance phenotypes among community urinary E. coli and highlight the need to explore strategies for their containment. © 2007 Elsevier Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/diagmicrobioen_US
dc.relation.ispartofDiagnostic Microbiology and Infectious Diseaseen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnti-Bacterial Agents - Pharmacologyen_US
dc.subject.meshDrug Resistance, Multiple, Bacterialen_US
dc.subject.meshEscherichia Coli - Drug Effects - Enzymologyen_US
dc.subject.meshEscherichia Coli Infections - Epidemiology - Microbiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOutpatientsen_US
dc.subject.meshPhenotypeen_US
dc.subject.meshPopulation Surveillanceen_US
dc.subject.meshUrinary Tract Infections - Epidemiology - Microbiologyen_US
dc.subject.meshBeta-Lactamases - Biosynthesisen_US
dc.titleAntimicrobial resistance in Escherichia coli outpatient urinary isolates from women: emerging multidrug resistance phenotypesen_US
dc.typeArticleen_US
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_US
dc.identifier.authorityHo, PL=rp00406en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.diagmicrobio.2007.06.012en_US
dc.identifier.pmid17888610en_US
dc.identifier.scopuseid_2-s2.0-36549006487en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-36549006487&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume59en_US
dc.identifier.issue4en_US
dc.identifier.spage439en_US
dc.identifier.epage445en_US
dc.identifier.isiWOS:000251809600014-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PL=7402211363en_US
dc.identifier.scopusauthoridWong, RCW=8612000100en_US
dc.identifier.scopusauthoridYip, KS=23020572500en_US
dc.identifier.scopusauthoridLoke, SL=55228176700en_US
dc.identifier.scopusauthoridLeung, MST=36928968000en_US
dc.identifier.scopusauthoridMak, GC=8883252800en_US
dc.identifier.scopusauthoridChow, FKH=36640352900en_US
dc.identifier.scopusauthoridTsang, KWT=7201555024en_US
dc.identifier.scopusauthoridQue, TL=7003786628en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats