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Article: Detection of a novel and highly divergent coronavims from Asian leopard cats and Chinese ferret badgers in southern China

TitleDetection of a novel and highly divergent coronavims from Asian leopard cats and Chinese ferret badgers in southern China
Authors
Issue Date2007
PublisherAmerican Society for Microbiology. The Journal's web site is located at http://jvi.asm.org/
Citation
Journal of Virology, 2007, v. 81 n. 13, p. 6920-6926 How to Cite?
AbstractSince an outbreak of severe acute respiratory syndrome (SARS) was averted in 2004, many novel coronaviruses have been recognized from different species, including humans. Bats have provided the most diverse assemblages of coronaviruses, suggesting that they may be the natural reservoir. Continued virological surveillance has proven to be the best way to avert this infectious disease at the source. Here we provide the first description of a previously unidentified coronavirus lineage detected from wild Asian leopard cats (Prionailurus bengalensis) and Chinese ferret badgers (Melogale moschata) during virological surveillance in southern China. Partial genome analysis revealed a typical coronavirus genome but with a unique putative accessory gene organization. Phylogenetic analyses revealed that the envelope, membrane, and nucleoprotein structural proteins and the two conserved replicase domains, putative RNA-dependent RNA polymerase and RNA helicase, of these novel coronaviruses were most closely related to those of group 3 coronaviruses identified from birds, while the spike protein gene was most closely related to that of group 1 coronaviruses from mammals. However, these viruses always fell into an outgroup phylogenetic relationship with respect to other coronaviruses and had low amino acid similarity to all known coronavirus groups, indicating that they diverged early in the evolutionary history of coronaviruses. These results suggest that these viruses may represent a previously unrecognized evolutionary pathway, or possibly an unidentified coronavirus group. This study demonstrates the importance of systematic virological surveillance in market animals for understanding the evolution and emergence of viruses with infectious potential. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Persistent Identifierhttp://hdl.handle.net/10722/157484
ISSN
2015 Impact Factor: 4.606
2015 SCImago Journal Rankings: 3.347
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorDong, BQen_HK
dc.contributor.authorLiu, Wen_HK
dc.contributor.authorFan, XHen_HK
dc.contributor.authorVijaykrishna, Den_HK
dc.contributor.authorTang, Xen_HK
dc.contributor.authorGao, Fen_HK
dc.contributor.authorLi, Len_HK
dc.contributor.authorLi, GJen_HK
dc.contributor.authorZhang, Jen_HK
dc.contributor.authorYang, LQen_HK
dc.contributor.authorPoon, LLMen_HK
dc.contributor.authorZhang, SYen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.contributor.authorSmith, GJen_HK
dc.contributor.authorChen, Hen_HK
dc.contributor.authorGuan, Yen_HK
dc.date.accessioned2012-08-08T08:50:25Z-
dc.date.available2012-08-08T08:50:25Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal of Virology, 2007, v. 81 n. 13, p. 6920-6926en_HK
dc.identifier.issn0022-538Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/157484-
dc.description.abstractSince an outbreak of severe acute respiratory syndrome (SARS) was averted in 2004, many novel coronaviruses have been recognized from different species, including humans. Bats have provided the most diverse assemblages of coronaviruses, suggesting that they may be the natural reservoir. Continued virological surveillance has proven to be the best way to avert this infectious disease at the source. Here we provide the first description of a previously unidentified coronavirus lineage detected from wild Asian leopard cats (Prionailurus bengalensis) and Chinese ferret badgers (Melogale moschata) during virological surveillance in southern China. Partial genome analysis revealed a typical coronavirus genome but with a unique putative accessory gene organization. Phylogenetic analyses revealed that the envelope, membrane, and nucleoprotein structural proteins and the two conserved replicase domains, putative RNA-dependent RNA polymerase and RNA helicase, of these novel coronaviruses were most closely related to those of group 3 coronaviruses identified from birds, while the spike protein gene was most closely related to that of group 1 coronaviruses from mammals. However, these viruses always fell into an outgroup phylogenetic relationship with respect to other coronaviruses and had low amino acid similarity to all known coronavirus groups, indicating that they diverged early in the evolutionary history of coronaviruses. These results suggest that these viruses may represent a previously unrecognized evolutionary pathway, or possibly an unidentified coronavirus group. This study demonstrates the importance of systematic virological surveillance in market animals for understanding the evolution and emergence of viruses with infectious potential. Copyright © 2007, American Society for Microbiology. All Rights Reserved.en_HK
dc.languageengen_US
dc.publisherAmerican Society for Microbiology. The Journal's web site is located at http://jvi.asm.org/en_HK
dc.relation.ispartofJournal of Virologyen_HK
dc.rightsJournal of Virology. Copyright © American Society for Microbiology.-
dc.subject.meshAnimalsen_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshChinaen_US
dc.subject.meshCoronavirus - Classification - Enzymology - Genetics - Isolation & Purificationen_US
dc.subject.meshDisease Outbreaks - Historyen_US
dc.subject.meshEvolution, Molecularen_US
dc.subject.meshFelidae - Virologyen_US
dc.subject.meshHistory, 21St Centuryen_US
dc.subject.meshHumansen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshMustelidae - Virologyen_US
dc.subject.meshPhylogenyen_US
dc.subject.meshRna Helicases - Geneticsen_US
dc.subject.meshRna Replicase - Geneticsen_US
dc.subject.meshSevere Acute Respiratory Syndrome - Epidemiology - History - Virologyen_US
dc.subject.meshViral Proteins - Geneticsen_US
dc.titleDetection of a novel and highly divergent coronavims from Asian leopard cats and Chinese ferret badgers in southern Chinaen_HK
dc.typeArticleen_HK
dc.identifier.emailDhanasekaran, V: veejay.here@gmail.comen_HK
dc.identifier.emailTang, X: tang-xc@yeah.neten_HK
dc.identifier.emailLi, L: lilifeng33@hotmail.comen_HK
dc.identifier.emailZhang, J: zhangajx@hkucc.hku.hken_HK
dc.identifier.emailPoon, LLM: llmpoon@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.emailSmith, GJ: gjsmith@hkucc.hku.hk-
dc.identifier.emailChen, H: hlchen@hku.hk-
dc.identifier.emailGuan, Y: yguan@hkucc.hku.hk-
dc.identifier.authorityZhang, J=rp00413en_HK
dc.identifier.authorityPoon, LLM=rp00484en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.identifier.authoritySmith, GJ=rp00444en_HK
dc.identifier.authorityChen, H=rp00383en_HK
dc.identifier.authorityGuan, Y=rp00397en_HK
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1128/JVI.00299-07en_HK
dc.identifier.pmid17459938-
dc.identifier.scopuseid_2-s2.0-34250858812en_HK
dc.identifier.hkuros130790-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34250858812&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume81en_HK
dc.identifier.issue13en_HK
dc.identifier.spage6920en_HK
dc.identifier.epage6926en_HK
dc.identifier.isiWOS:000247404900015-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridDong, BQ=9333345200en_HK
dc.identifier.scopusauthoridLiu, W=7407339395en_HK
dc.identifier.scopusauthoridFan, XH=35227217200en_HK
dc.identifier.scopusauthoridVijaykrishna, D=12752817700en_HK
dc.identifier.scopusauthoridTang, XC=22942258000en_HK
dc.identifier.scopusauthoridGao, F=34769702200en_HK
dc.identifier.scopusauthoridLi, LF=14045423100en_HK
dc.identifier.scopusauthoridLi, GJ=14045214500en_HK
dc.identifier.scopusauthoridZhang, JX=12752135600en_HK
dc.identifier.scopusauthoridYang, LQ=16647822100en_HK
dc.identifier.scopusauthoridPoon, LLM=7005441747en_HK
dc.identifier.scopusauthoridZhang, SY=35212214400en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK
dc.identifier.scopusauthoridSmith, GJD=8344015800en_HK
dc.identifier.scopusauthoridChen, H=26643315400en_HK
dc.identifier.scopusauthoridGuan, Y=7202924055en_HK
dc.customcontrol.immutablesml 130524-

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