File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Catabacter hongkongensis gen. nov., sp. nov., isolated from blood cultures of patients from Hong Kong and Canada

TitleCatabacter hongkongensis gen. nov., sp. nov., isolated from blood cultures of patients from Hong Kong and Canada
Authors
Issue Date2007
Citation
Journal Of Clinical Microbiology, 2007, v. 45 n. 2, p. 395-401 How to Cite?
Abstract
Four bacterial isolates were recovered from the blood cultures of four patients, two of whom were from Hong Kong and two of whom were from Canada. The two Hong Kong strains were isolated from a 48-year-old man with intestinal obstruction and secondary sepsis (strain HKU16T) and from a 39-year-old man with acute appendicitis (strain HKU17), while the two Canadian strains were isolated from a 74-year-old man with biliary sepsis (strain CA1) and from a 66-year-old woman with metastatic carcinoma and sepsis (strain CA2). While the first three patients survived, the last patient died 2 weeks after the episode of bacteremia. All four isolates are strictly anaerobic, nonsporulating, gram-positive coccobacilli that were unidentified by conventional phenotypic tests and commercial identification systems. They grow on sheep blood agar as nonhemolytic pinpoint colonies after 48 h of incubation at 37°C in an anaerobic environment. All are catalase positive and motile, with flagella. They produce acid from arabinose, glucose, mannose, and xylose. They do not produce indole or reduce nitrate. They are sensitive to penicillin, vancomycin, and metronidazole but resistant to cefotaxime. 16S rRNA gene sequence analysis showed 16.0%, 16.8%, and 21.0% base differences from Clostridium propionicum, Clostridium neopropionicum, and Atopobium minutum, respectively. The G+C content of strain HKU16T is 40.2% ± 2.2%. Based on their phylogenetic affiliation, unique G+C content, and phenotypic characteristics, we propose a new genus and species, Catabacter hongkongensis gen. nov., sp. nov., to describe the bacterium, for which HKU16 is the type strain, and suggest that it be assigned to a new family, Catabacteriaceae. The gastrointestinal tract was probably the source of the bacterium for at least three of the four patients. The isolation of a catalase-positive, motile, nonsporulating, anaerobic gram-positive bacillus in clinical laboratories should raise the possibility of C. hongkongensis. Further studies should be performed to ascertain the epidemiology and other disease associations of this bacterium. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Persistent Identifierhttp://hdl.handle.net/10722/157472
ISSN
2013 Impact Factor: 4.232
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, SKPen_US
dc.contributor.authorMcnabb, Aen_US
dc.contributor.authorWoo, GKSen_US
dc.contributor.authorHoang, Len_US
dc.contributor.authorFung, AMYen_US
dc.contributor.authorChung, LMWen_US
dc.contributor.authorWoo, PCYen_US
dc.contributor.authorYuen, KYen_US
dc.date.accessioned2012-08-08T08:50:15Z-
dc.date.available2012-08-08T08:50:15Z-
dc.date.issued2007en_US
dc.identifier.citationJournal Of Clinical Microbiology, 2007, v. 45 n. 2, p. 395-401en_US
dc.identifier.issn0095-1137en_US
dc.identifier.urihttp://hdl.handle.net/10722/157472-
dc.description.abstractFour bacterial isolates were recovered from the blood cultures of four patients, two of whom were from Hong Kong and two of whom were from Canada. The two Hong Kong strains were isolated from a 48-year-old man with intestinal obstruction and secondary sepsis (strain HKU16T) and from a 39-year-old man with acute appendicitis (strain HKU17), while the two Canadian strains were isolated from a 74-year-old man with biliary sepsis (strain CA1) and from a 66-year-old woman with metastatic carcinoma and sepsis (strain CA2). While the first three patients survived, the last patient died 2 weeks after the episode of bacteremia. All four isolates are strictly anaerobic, nonsporulating, gram-positive coccobacilli that were unidentified by conventional phenotypic tests and commercial identification systems. They grow on sheep blood agar as nonhemolytic pinpoint colonies after 48 h of incubation at 37°C in an anaerobic environment. All are catalase positive and motile, with flagella. They produce acid from arabinose, glucose, mannose, and xylose. They do not produce indole or reduce nitrate. They are sensitive to penicillin, vancomycin, and metronidazole but resistant to cefotaxime. 16S rRNA gene sequence analysis showed 16.0%, 16.8%, and 21.0% base differences from Clostridium propionicum, Clostridium neopropionicum, and Atopobium minutum, respectively. The G+C content of strain HKU16T is 40.2% ± 2.2%. Based on their phylogenetic affiliation, unique G+C content, and phenotypic characteristics, we propose a new genus and species, Catabacter hongkongensis gen. nov., sp. nov., to describe the bacterium, for which HKU16 is the type strain, and suggest that it be assigned to a new family, Catabacteriaceae. The gastrointestinal tract was probably the source of the bacterium for at least three of the four patients. The isolation of a catalase-positive, motile, nonsporulating, anaerobic gram-positive bacillus in clinical laboratories should raise the possibility of C. hongkongensis. Further studies should be performed to ascertain the epidemiology and other disease associations of this bacterium. Copyright © 2007, American Society for Microbiology. All Rights Reserved.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Clinical Microbiologyen_US
dc.rightsJournal of Clinical Microbiology. Copyright © American Society for Microbiology.-
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnaerobiosisen_US
dc.subject.meshBacteremia - Epidemiology - Microbiologyen_US
dc.subject.meshBacterial Typing Techniquesen_US
dc.subject.meshBase Compositionen_US
dc.subject.meshBlood - Microbiologyen_US
dc.subject.meshCanada - Epidemiologyen_US
dc.subject.meshCulture Mediaen_US
dc.subject.meshFemaleen_US
dc.subject.meshGram-Positive Bacteria - Classification - Genetics - Isolation & Purificationen_US
dc.subject.meshGram-Positive Bacterial Infections - Epidemiology - Microbiologyen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPhenotypeen_US
dc.subject.meshPhylogenyen_US
dc.subject.meshRna, Ribosomal, 16S - Geneticsen_US
dc.subject.meshSequence Analysis, Dnaen_US
dc.titleCatabacter hongkongensis gen. nov., sp. nov., isolated from blood cultures of patients from Hong Kong and Canadaen_US
dc.typeArticleen_US
dc.identifier.emailLau, SKP:skplau@hkucc.hku.hken_US
dc.identifier.emailWoo, PCY:pcywoo@hkucc.hku.hken_US
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_US
dc.identifier.authorityLau, SKP=rp00486en_US
dc.identifier.authorityWoo, PCY=rp00430en_US
dc.identifier.authorityYuen, KY=rp00366en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1128/JCM.01831-06en_US
dc.identifier.pmid17122022en_US
dc.identifier.scopuseid_2-s2.0-33847022234en_US
dc.identifier.hkuros127781-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33847022234&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume45en_US
dc.identifier.issue2en_US
dc.identifier.spage395en_US
dc.identifier.epage401en_US
dc.identifier.isiWOS:000244270000022-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLau, SKP=7401596211en_US
dc.identifier.scopusauthoridMcNabb, A=7004662210en_US
dc.identifier.scopusauthoridWoo, GKS=7006485416en_US
dc.identifier.scopusauthoridHoang, L=7003369499en_US
dc.identifier.scopusauthoridFung, AMY=7101926801en_US
dc.identifier.scopusauthoridChung, LMW=15847898900en_US
dc.identifier.scopusauthoridWoo, PCY=7201801340en_US
dc.identifier.scopusauthoridYuen, KY=36078079100en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats