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Article: Fluoroquinolone and other antimicriobial resistance in invasive pneumococci, Hong Kong, 1995-2001

TitleFluoroquinolone and other antimicriobial resistance in invasive pneumococci, Hong Kong, 1995-2001
Authors
Issue Date2004
PublisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm
Citation
Emerging Infectious Diseases, 2004, v. 10 n. 7, p. 1250-1257 How to Cite?
AbstractWe determined the susceptibilities of 265 invasive isolates of pneumococci obtained during 1995 to 2001 in Hong Kong to 11 antimicrobial agents and their serotypes. Overall, 62.6% isolates were susceptible to penicillin, 20% were intermediately resistant, and 17.4% were resistant. The overall prevalence of levofloxacin resistance (MIC ≥8 μg/mL) was 3.8% but increased to 15.2% among the penicillin-resistant isolates. All levofloxacin-resistant isolates were clonally related; had reduced susceptibility to penicillin, cefotaxime, and clarithromycin; and were derived from adults >50 years of age. Of the penicillin-nonsusceptible pneumococci, 90% from children ≤5 years of age and 54.8% from persons of all ages were of serotypes that are included in the 7-valent pneumococcal conjugate vaccine; 93.5% from children ≤5 years of age and 93% from persons of all ages were of serotypes that are included in the 23-valent polysaccharide vaccine.
Persistent Identifierhttp://hdl.handle.net/10722/157433
ISSN
2014 Impact Factor: 6.751
2014 SCImago Journal Rankings: 2.943
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHo, PLen_HK
dc.contributor.authorQue, TLen_HK
dc.contributor.authorChiu, SSen_HK
dc.contributor.authorYung, RWHen_HK
dc.contributor.authorNg, TKen_HK
dc.contributor.authorTsang, DNCen_HK
dc.contributor.authorSeto, WHen_HK
dc.contributor.authorLau, YLen_HK
dc.date.accessioned2012-08-08T08:49:55Z-
dc.date.available2012-08-08T08:49:55Z-
dc.date.issued2004en_HK
dc.identifier.citationEmerging Infectious Diseases, 2004, v. 10 n. 7, p. 1250-1257en_HK
dc.identifier.issn1080-6040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/157433-
dc.description.abstractWe determined the susceptibilities of 265 invasive isolates of pneumococci obtained during 1995 to 2001 in Hong Kong to 11 antimicrobial agents and their serotypes. Overall, 62.6% isolates were susceptible to penicillin, 20% were intermediately resistant, and 17.4% were resistant. The overall prevalence of levofloxacin resistance (MIC ≥8 μg/mL) was 3.8% but increased to 15.2% among the penicillin-resistant isolates. All levofloxacin-resistant isolates were clonally related; had reduced susceptibility to penicillin, cefotaxime, and clarithromycin; and were derived from adults >50 years of age. Of the penicillin-nonsusceptible pneumococci, 90% from children ≤5 years of age and 54.8% from persons of all ages were of serotypes that are included in the 7-valent pneumococcal conjugate vaccine; 93.5% from children ≤5 years of age and 93% from persons of all ages were of serotypes that are included in the 23-valent polysaccharide vaccine.en_HK
dc.languageengen_US
dc.publisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htmen_HK
dc.relation.ispartofEmerging Infectious Diseasesen_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Bacterial Agents - Pharmacologyen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDrug Resistance, Bacterial - Geneticsen_US
dc.subject.meshFluoroquinolones - Pharmacologyen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPneumococcal Infections - Epidemiology - Microbiologyen_US
dc.subject.meshSerotypingen_US
dc.subject.meshStreptococcus Pneumoniae - Classification - Drug Effectsen_US
dc.titleFluoroquinolone and other antimicriobial resistance in invasive pneumococci, Hong Kong, 1995-2001en_HK
dc.typeArticleen_HK
dc.identifier.emailHo, PL:plho@hkucc.hku.hken_HK
dc.identifier.emailChiu, SS:ssschiu@hkucc.hku.hken_HK
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.identifier.authorityChiu, SS=rp00421en_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid15324545en_US
dc.identifier.scopuseid_2-s2.0-3042703738en_HK
dc.identifier.hkuros94814-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-3042703738&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1250en_HK
dc.identifier.epage1257en_HK
dc.identifier.isiWOS:000222456800010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridQue, TL=7003786628en_HK
dc.identifier.scopusauthoridChiu, SS=7202291500en_HK
dc.identifier.scopusauthoridYung, RWH=7005594277en_HK
dc.identifier.scopusauthoridNg, TK=7402229817en_HK
dc.identifier.scopusauthoridTsang, DNC=7005609132en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK

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