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Article: Development of a standard treatment protocol for severe acute respiratory syndrome

TitleDevelopment of a standard treatment protocol for severe acute respiratory syndrome
Authors
Issue Date2003
PublisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lancet
Citation
Lancet, 2003, v. 361 n. 9369, p. 1615-1617 How to Cite?
AbstractA series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterials and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered on antibacterial treatment alone, 17 showed rapid and sustained responses, and 13 achieved improvement with step-up or pulsed methylprednisolone. Four patients required short periods of non-invasive ventilation. No patient required intubation or mechanical ventilation. There was no mortality or treatment morbidity in this series.
Persistent Identifierhttp://hdl.handle.net/10722/157360
ISSN
2015 Impact Factor: 44.002
2015 SCImago Journal Rankings: 14.638
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSo, LKYen_US
dc.contributor.authorLau, ACWen_US
dc.contributor.authorYam, LYCen_US
dc.contributor.authorCheung, TMTen_US
dc.contributor.authorPoon, Een_US
dc.contributor.authorYung, RWHen_US
dc.contributor.authorYuen, KYen_US
dc.date.accessioned2012-08-08T08:49:19Z-
dc.date.available2012-08-08T08:49:19Z-
dc.date.issued2003en_US
dc.identifier.citationLancet, 2003, v. 361 n. 9369, p. 1615-1617en_US
dc.identifier.issn0140-6736en_US
dc.identifier.urihttp://hdl.handle.net/10722/157360-
dc.description.abstractA series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterials and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered on antibacterial treatment alone, 17 showed rapid and sustained responses, and 13 achieved improvement with step-up or pulsed methylprednisolone. Four patients required short periods of non-invasive ventilation. No patient required intubation or mechanical ventilation. There was no mortality or treatment morbidity in this series.en_US
dc.languageengen_US
dc.publisherThe Lancet Publishing Group. The Journal's web site is located at http://www.elsevier.com/locate/lanceten_US
dc.relation.ispartofLanceten_US
dc.subject.meshAdulten_US
dc.subject.meshAnti-Bacterial Agents - Therapeutic Useen_US
dc.subject.meshDrug Administration Scheduleen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMethylprednisolone - Therapeutic Useen_US
dc.subject.meshRibavirin - Therapeutic Useen_US
dc.subject.meshSevere Acute Respiratory Syndrome - Drug Therapy - Physiopathologyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleDevelopment of a standard treatment protocol for severe acute respiratory syndromeen_US
dc.typeArticleen_US
dc.identifier.emailYuen, KY:kyyuen@hkucc.hku.hken_US
dc.identifier.authorityYuen, KY=rp00366en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0140-6736(03)13265-5en_US
dc.identifier.pmid12747883-
dc.identifier.scopuseid_2-s2.0-0038137600en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038137600&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume361en_US
dc.identifier.issue9369en_US
dc.identifier.spage1615en_US
dc.identifier.epage1617en_US
dc.identifier.isiWOS:000182746300013-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridSo, LKY=35985409300en_US
dc.identifier.scopusauthoridLau, ACW=7202626205en_US
dc.identifier.scopusauthoridYam, LYC=7102764741en_US
dc.identifier.scopusauthoridCheung, TMT=7103334508en_US
dc.identifier.scopusauthoridPoon, E=7003615957en_US
dc.identifier.scopusauthoridYung, RWH=7005594277en_US
dc.identifier.scopusauthoridYuen, KY=36078079100en_US

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