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- Publisher Website: 10.1097/00002030-200212060-00016
- Scopus: eid_2-s2.0-0037032906
- PMID: 12461425
- WOS: WOS:000180146000016
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Article: Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections
Title | Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections |
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Authors | |
Issue Date | 2002 |
Publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.AIDSonline.com |
Citation | Aids, 2002, v. 16 n. 18, p. 2480-2482 How to Cite? |
Abstract | Seven mutant alleles of the CCR5 gene were identified in southern Chinese, six of which were novel mutations. The most common was a heterozygous mutant allele (R223Q) found in 21 healthy donors and 20 HIV patients. No significant difference in the mutant frequency was observed between healthy donors (0.044) and HIV patients (0.041), but the frequency was significantly higher in asymptomatic (0.066) than in symptomatic HIV patients (0.019). |
Persistent Identifier | http://hdl.handle.net/10722/157345 |
ISSN | 2023 Impact Factor: 3.4 2023 SCImago Journal Rankings: 1.401 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zheng, BJ | en_US |
dc.contributor.author | Zhao, XY | en_US |
dc.contributor.author | Zhu, NS | en_US |
dc.contributor.author | Chan, CP | en_US |
dc.contributor.author | Wong, KH | en_US |
dc.contributor.author | Chan, KCW | en_US |
dc.contributor.author | Yam, WC | en_US |
dc.contributor.author | Yuen, KY | en_US |
dc.contributor.author | Lee, SS | en_US |
dc.date.accessioned | 2012-08-08T08:49:05Z | - |
dc.date.available | 2012-08-08T08:49:05Z | - |
dc.date.issued | 2002 | en_US |
dc.identifier.citation | Aids, 2002, v. 16 n. 18, p. 2480-2482 | en_US |
dc.identifier.issn | 0269-9370 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/157345 | - |
dc.description.abstract | Seven mutant alleles of the CCR5 gene were identified in southern Chinese, six of which were novel mutations. The most common was a heterozygous mutant allele (R223Q) found in 21 healthy donors and 20 HIV patients. No significant difference in the mutant frequency was observed between healthy donors (0.044) and HIV patients (0.041), but the frequency was significantly higher in asymptomatic (0.066) than in symptomatic HIV patients (0.019). | en_US |
dc.language | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins. The Journal's web site is located at http://www.AIDSonline.com | en_US |
dc.relation.ispartof | AIDS | en_US |
dc.rights | AIDS. Copyright © Lippincott Williams & Wilkins. | - |
dc.subject.mesh | China - Ethnology | en_US |
dc.subject.mesh | Disease Progression | en_US |
dc.subject.mesh | Gene Frequency | en_US |
dc.subject.mesh | Hiv Infections - Genetics | en_US |
dc.subject.mesh | Hiv-1 - Genetics | en_US |
dc.subject.mesh | Heterozygote | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Mutation - Genetics | en_US |
dc.subject.mesh | Point Mutation - Genetics | en_US |
dc.subject.mesh | Polymorphism, Genetic - Genetics | en_US |
dc.subject.mesh | Receptors, Ccr5 - Genetics | en_US |
dc.title | Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections | en_US |
dc.type | Article | en_US |
dc.identifier.email | Zheng, BJ: bzheng@hkucc.hku.hk | en_US |
dc.identifier.email | Yam, WC: wcyam@hkucc.hku.hk | en_US |
dc.identifier.email | Yuen, KY: kyyuen@hkucc.hku.hk | en_US |
dc.identifier.authority | Zheng, BJ=rp00353 | en_US |
dc.identifier.authority | Yam, WC=rp00313 | en_US |
dc.identifier.authority | Yuen, KY=rp00366 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1097/00002030-200212060-00016 | en_US |
dc.identifier.pmid | 12461425 | - |
dc.identifier.scopus | eid_2-s2.0-0037032906 | en_US |
dc.identifier.hkuros | 106045 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0037032906&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 16 | en_US |
dc.identifier.issue | 18 | en_US |
dc.identifier.spage | 2480 | en_US |
dc.identifier.epage | 2482 | en_US |
dc.identifier.isi | WOS:000180146000016 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Zheng, BJ=7201780588 | en_US |
dc.identifier.scopusauthorid | Zhao, XY=7407577215 | en_US |
dc.identifier.scopusauthorid | Zhu, NS=7201449513 | en_US |
dc.identifier.scopusauthorid | Chan, CP=7404813842 | en_US |
dc.identifier.scopusauthorid | Wong, KH=7404758411 | en_US |
dc.identifier.scopusauthorid | ChiWai Chan, K=6504413647 | en_US |
dc.identifier.scopusauthorid | Yam, WC=7004281720 | en_US |
dc.identifier.scopusauthorid | Yuen, KY=36078079100 | en_US |
dc.identifier.scopusauthorid | Lee, SS=7601394467 | en_US |
dc.identifier.issnl | 0269-9370 | - |