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Article: Surface characteristics, properties and in vitro biological assessment of a NiTi shape memory alloy after high temperature heat treatment or surface H 2O 2-oxidation: A comparative study

TitleSurface characteristics, properties and in vitro biological assessment of a NiTi shape memory alloy after high temperature heat treatment or surface H 2O 2-oxidation: A comparative study
Authors
KeywordsBiomaterials
Coatings
Shape Memory Effects
Surface Properties
Issue Date2011
PublisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/matchemphys
Citation
Materials Chemistry And Physics, 2011, v. 130 n. 1-2, p. 45-58 How to Cite?
AbstractTo improve the biocompatibility and bioactivity of a NiTi shape memory alloy (SMA), an oxide layer was fabricated on its surface using either a heat treatment at 600 °C for 1 h or surface H 2O 2-oxidation with subsequent hot water aging. The oxide layer synthesized by the heat treatment was not uniform and had a thickness from 1.5 μm to 4.0 μm, whereas the titania gel layer fabricated through the H 2O 2-oxidation method was homogeneous and about 4.0 μm thick. The oxide layer formed on heat treated NiTi SMA was composed of both anatase and rutile titania with a small amount of Ni 2O 3. On the contrary, the gel layer made by H 2O 2-oxidation mainly consisted of poorly crystalline anatase and was relatively Ni-free. Abundant Ti-OH functional groups existed on the titania gel layer, contributing to the improvement of bioactivity. Mechanical properties of the two oxide layers were drastically different. The phase transformation temperatures of NiTi SMA were altered by the heat treatment. The titania gel layer on H 2O 2-oxidized NiTi SMA was more chemically stable than the oxide layer on heat treated NiTi SMA. Although both the heat treatment and the H 2O 2-oxidation method greatly improved the bioactivity of NiTi SMA, H 2O 2-oxidized samples were found to be more bioactive. Moreover, in vitro cytotoxicity evaluation based on MTT assay revealed that both heat treated and H 2O 2-oxidized samples did not have acute cytotoxicity. Results from live and dead cells staining showed that more MCF-7 cells attached and spread extensively on H 2O 2-oxidized samples in comparison to either heat treated or untreated samples. © 2011 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/157140
ISSN
2015 Impact Factor: 2.101
2015 SCImago Journal Rankings: 0.733
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong (HKU)
Funding Information:

This work was supported by a research grant from The University of Hong Kong (HKU) in its Basic Research Program. The authors thank technical staff in the Department of Mechanical Engineering, HKU, and the Bioelectronics Lab, Institute of Microelectronics for their assistance.

References

 

DC FieldValueLanguage
dc.contributor.authorSun, Ten_US
dc.contributor.authorWang, Men_US
dc.contributor.authorLee, WCen_US
dc.date.accessioned2012-08-08T08:45:29Z-
dc.date.available2012-08-08T08:45:29Z-
dc.date.issued2011en_US
dc.identifier.citationMaterials Chemistry And Physics, 2011, v. 130 n. 1-2, p. 45-58en_US
dc.identifier.issn0254-0584en_US
dc.identifier.urihttp://hdl.handle.net/10722/157140-
dc.description.abstractTo improve the biocompatibility and bioactivity of a NiTi shape memory alloy (SMA), an oxide layer was fabricated on its surface using either a heat treatment at 600 °C for 1 h or surface H 2O 2-oxidation with subsequent hot water aging. The oxide layer synthesized by the heat treatment was not uniform and had a thickness from 1.5 μm to 4.0 μm, whereas the titania gel layer fabricated through the H 2O 2-oxidation method was homogeneous and about 4.0 μm thick. The oxide layer formed on heat treated NiTi SMA was composed of both anatase and rutile titania with a small amount of Ni 2O 3. On the contrary, the gel layer made by H 2O 2-oxidation mainly consisted of poorly crystalline anatase and was relatively Ni-free. Abundant Ti-OH functional groups existed on the titania gel layer, contributing to the improvement of bioactivity. Mechanical properties of the two oxide layers were drastically different. The phase transformation temperatures of NiTi SMA were altered by the heat treatment. The titania gel layer on H 2O 2-oxidized NiTi SMA was more chemically stable than the oxide layer on heat treated NiTi SMA. Although both the heat treatment and the H 2O 2-oxidation method greatly improved the bioactivity of NiTi SMA, H 2O 2-oxidized samples were found to be more bioactive. Moreover, in vitro cytotoxicity evaluation based on MTT assay revealed that both heat treated and H 2O 2-oxidized samples did not have acute cytotoxicity. Results from live and dead cells staining showed that more MCF-7 cells attached and spread extensively on H 2O 2-oxidized samples in comparison to either heat treated or untreated samples. © 2011 Elsevier B.V. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/matchemphysen_US
dc.relation.ispartofMaterials Chemistry and Physicsen_US
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Materials Chemistry and Physics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Materials Chemistry and Physics, [VOL 130, ISSUE 1-2, 2011] DOI 10.1016/j.matchemphys.2011.05.003-
dc.subjectBiomaterialsen_US
dc.subjectCoatingsen_US
dc.subjectShape Memory Effectsen_US
dc.subjectSurface Propertiesen_US
dc.titleSurface characteristics, properties and in vitro biological assessment of a NiTi shape memory alloy after high temperature heat treatment or surface H 2O 2-oxidation: A comparative studyen_US
dc.typeArticleen_US
dc.identifier.emailWang, M:memwang@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.matchemphys.2011.05.003en_US
dc.identifier.scopuseid_2-s2.0-80052602366en_US
dc.identifier.hkuros207447-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80052602366&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume130en_US
dc.identifier.issue1-2en_US
dc.identifier.spage45en_US
dc.identifier.epage58en_US
dc.identifier.isiWOS:000295601700009-
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridSun, T=7402922748en_US
dc.identifier.scopusauthoridWang, M=15749714100en_US
dc.identifier.scopusauthoridLee, WC=38862100400en_US
dc.identifier.citeulike9807001-

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