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Article: Plasma-sprayed calcium phosphate particles with high bioactivity and their use in bioactive scaffolds

TitlePlasma-sprayed calcium phosphate particles with high bioactivity and their use in bioactive scaffolds
Authors
Issue Date2002
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/biomaterials
Citation
Biomaterials, 2002, v. 23 n. 13, p. 2623-2629 How to Cite?
AbstractHighly crystalline feedstock hydroxyapatite (HA) particles with irregular shapes were spheroidized by plasma spraying them onto the surface of ice blocks or into water. The spherical Ca-P particles thus produced contained various amounts of the amorphous phase which were controlled by the stand-off distance between the spray nozzle and the surface of ice blocks or water. The smooth surface morphology without cracks of spherical Ca-P particles indicated that there were very low thermal stresses in these particles. Plasma-sprayed Ca-P particles were highly bioactive due to their amorphous component and hence quickly induced the formation of bone-like apatite on their surfaces after they were immersed in an acellular simulated body fluid at 36.5°C. Bone-like apatite nucleated on dissolved surface (due to the amorphous phase) of individual Ca-P particles and grew to coalesce between neighboring Ca-P particles thus forming an integrated apatite plate. Bioactive and biodegradable composite scaffolds were produced by incorporating plasma-sprayed Ca-P particles into a degradable polymer. In vitro experiments showed that plasma-sprayed Ca-P particles enhanced the formation of bone-like apatite on the pore surface of Ca-P/PLLA composite scaffolds. © 2002 Elsevier Science Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/156624
ISSN
2015 Impact Factor: 8.387
2015 SCImago Journal Rankings: 3.565
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWeng, Jen_US
dc.contributor.authorWang, Men_US
dc.contributor.authorChen, Jen_US
dc.date.accessioned2012-08-08T08:43:15Z-
dc.date.available2012-08-08T08:43:15Z-
dc.date.issued2002en_US
dc.identifier.citationBiomaterials, 2002, v. 23 n. 13, p. 2623-2629en_US
dc.identifier.issn0142-9612en_US
dc.identifier.urihttp://hdl.handle.net/10722/156624-
dc.description.abstractHighly crystalline feedstock hydroxyapatite (HA) particles with irregular shapes were spheroidized by plasma spraying them onto the surface of ice blocks or into water. The spherical Ca-P particles thus produced contained various amounts of the amorphous phase which were controlled by the stand-off distance between the spray nozzle and the surface of ice blocks or water. The smooth surface morphology without cracks of spherical Ca-P particles indicated that there were very low thermal stresses in these particles. Plasma-sprayed Ca-P particles were highly bioactive due to their amorphous component and hence quickly induced the formation of bone-like apatite on their surfaces after they were immersed in an acellular simulated body fluid at 36.5°C. Bone-like apatite nucleated on dissolved surface (due to the amorphous phase) of individual Ca-P particles and grew to coalesce between neighboring Ca-P particles thus forming an integrated apatite plate. Bioactive and biodegradable composite scaffolds were produced by incorporating plasma-sprayed Ca-P particles into a degradable polymer. In vitro experiments showed that plasma-sprayed Ca-P particles enhanced the formation of bone-like apatite on the pore surface of Ca-P/PLLA composite scaffolds. © 2002 Elsevier Science Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/biomaterialsen_US
dc.relation.ispartofBiomaterialsen_US
dc.rightsBiomaterials. Copyright © Elsevier BV.-
dc.subject.meshBiocompatible Materialsen_US
dc.subject.meshBone Substitutes - Chemistryen_US
dc.subject.meshCalcium Phosphates - Chemistryen_US
dc.subject.meshDurapatite - Chemistryen_US
dc.subject.meshLactic Acid - Chemistryen_US
dc.subject.meshMicroscopy, Electron, Scanningen_US
dc.subject.meshModels, Chemicalen_US
dc.subject.meshPolymers - Chemistryen_US
dc.subject.meshX-Ray Diffractionen_US
dc.titlePlasma-sprayed calcium phosphate particles with high bioactivity and their use in bioactive scaffoldsen_US
dc.typeArticleen_US
dc.identifier.emailWang, M: memwang@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0142-9612(01)00393-3en_US
dc.identifier.pmid12059011-
dc.identifier.scopuseid_2-s2.0-0036244817en_US
dc.identifier.hkuros110853-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036244817&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue13en_US
dc.identifier.spage2623en_US
dc.identifier.epage2629en_US
dc.identifier.isiWOS:000175718600001-
dc.publisher.placeNetherlandsen_US
dc.identifier.scopusauthoridWeng, J=7202292060en_US
dc.identifier.scopusauthoridWang, M=15749714100en_US
dc.identifier.scopusauthoridChen, J=35309782300en_US

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