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Article: Developing tricalcium phosphate/polyhydroxybutyrate composite as a new biodegradable material for clinical applications

TitleDeveloping tricalcium phosphate/polyhydroxybutyrate composite as a new biodegradable material for clinical applications
Authors
Issue Date2001
PublisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net
Citation
Key Engineering Materials, 2001, v. 192-195, p. 741-744 How to Cite?
AbstractTwo biodegradable materials, namely, tricalcium phosphate (TCP) and polyhydroxybutyrate (PHB), were used to produce a new composite material for tissue replacement/regeneration. Commercially available TCP and PHB were used, with both materials being in the form of fine powders. They were characterised prior to composite production. TCP/PHB composite containing up to 30vol% of TCP was produced. Manufacture of the composite consisted of compounding, milling, drying and compression moulding. During the manufacturing process, the temperature and time for maintaining PHB in the molten state were carefully controlled as PHB is very heat-sensitive. Thermogravimetric analysis (TGA) of the composite indicated that intended compositions for the composite had been achieved. Examinations using a scanning electron microscope (SEM) revealed that TCP particles were well distributed in compounded and compression moulded materials. Differential scanning calorimetry (DSC) analysis showed that an increase in the TCP content resulted in decreases in both the melting temperature and the crystallinity of PHB. An ascending trend of microhardness was observed for TCP/PHB with an increase in the TCP volume percentage. Dynamic mechanical analysis (DMA) showed that the storage modulus increased from 2.76GPa for the unfilled PHB to 4.80GPa for the composite containing 20vol% of TCP.
Persistent Identifierhttp://hdl.handle.net/10722/156583
ISSN
2005 Impact Factor: 0.224
2015 SCImago Journal Rankings: 0.173
References

 

DC FieldValueLanguage
dc.contributor.authorWang, Men_US
dc.contributor.authorWeng, Jen_US
dc.contributor.authorNi, Jen_US
dc.contributor.authorGoh, CHen_US
dc.contributor.authorWang, CXen_US
dc.date.accessioned2012-08-08T08:43:04Z-
dc.date.available2012-08-08T08:43:04Z-
dc.date.issued2001en_US
dc.identifier.citationKey Engineering Materials, 2001, v. 192-195, p. 741-744en_US
dc.identifier.issn1013-9826en_US
dc.identifier.urihttp://hdl.handle.net/10722/156583-
dc.description.abstractTwo biodegradable materials, namely, tricalcium phosphate (TCP) and polyhydroxybutyrate (PHB), were used to produce a new composite material for tissue replacement/regeneration. Commercially available TCP and PHB were used, with both materials being in the form of fine powders. They were characterised prior to composite production. TCP/PHB composite containing up to 30vol% of TCP was produced. Manufacture of the composite consisted of compounding, milling, drying and compression moulding. During the manufacturing process, the temperature and time for maintaining PHB in the molten state were carefully controlled as PHB is very heat-sensitive. Thermogravimetric analysis (TGA) of the composite indicated that intended compositions for the composite had been achieved. Examinations using a scanning electron microscope (SEM) revealed that TCP particles were well distributed in compounded and compression moulded materials. Differential scanning calorimetry (DSC) analysis showed that an increase in the TCP content resulted in decreases in both the melting temperature and the crystallinity of PHB. An ascending trend of microhardness was observed for TCP/PHB with an increase in the TCP volume percentage. Dynamic mechanical analysis (DMA) showed that the storage modulus increased from 2.76GPa for the unfilled PHB to 4.80GPa for the composite containing 20vol% of TCP.en_US
dc.languageengen_US
dc.publisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.neten_US
dc.relation.ispartofKey Engineering Materialsen_US
dc.titleDeveloping tricalcium phosphate/polyhydroxybutyrate composite as a new biodegradable material for clinical applicationsen_US
dc.typeArticleen_US
dc.identifier.emailWang, M:memwang@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0035151487en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035151487&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume192-195en_US
dc.identifier.spage741en_US
dc.identifier.epage744en_US
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridWang, M=15749714100en_US
dc.identifier.scopusauthoridWeng, J=7202292060en_US
dc.identifier.scopusauthoridNi, J=8859102900en_US
dc.identifier.scopusauthoridGoh, CH=36785574200en_US
dc.identifier.scopusauthoridWang, CX=15735379100en_US

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