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Article: Can intensity-modulated radiotherapy preserve oral health-related quality of life of nasopharyngeal carcinoma patients?

TitleCan intensity-modulated radiotherapy preserve oral health-related quality of life of nasopharyngeal carcinoma patients?
Authors
Issue Date2012
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ijrobp
Citation
International Journal of Radiation Oncology - Biology - Physics, 2012, v. 83 n. 2, p. e213-e221 How to Cite?
AbstractPurpose: To investigate the changes in salivary function and oral health-related quality of life for patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy (IMRT). Methods and Materials: A total of 57 patients with early-stage nasopharyngeal carcinoma received IMRT. The parotid and whole saliva flow was measured, and the Medical Outcomes Study 36-item short form, European Organization for Research and Treatment of Cancer Quality of Life questionnaire-C30, European Organization for Research and Treatment of Cancer Quality of Life questionnaire 35-item head-and-neck module, and Oral Health Impact Profile questionnaires were completed at baseline and 2, 6, 12, 18, and 24 months after IMRT. Results: Parotid saliva flow recovered fully after 1 year and maintained. Whole saliva flow recovered partially to 40% of baseline. A general trend of deterioration in most quality of life scales was observed after IMRT, followed by gradual recovery. Persistent oral-related symptoms were found 2 years after treatment. Conclusion: IMRT for early-stage nasopharyngeal carcinoma could only partially preserve the whole salivary function and oral health-related quality of life. © 2012 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/154726
ISSN
2015 Impact Factor: 4.495
2015 SCImago Journal Rankings: 2.274
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPow, EHNen_US
dc.contributor.authorKwong, DLWen_US
dc.contributor.authorSham, JSTen_US
dc.contributor.authorLee, VHFen_US
dc.contributor.authorNg, SCYen_US
dc.date.accessioned2012-08-08T08:27:09Z-
dc.date.available2012-08-08T08:27:09Z-
dc.date.issued2012en_US
dc.identifier.citationInternational Journal of Radiation Oncology - Biology - Physics, 2012, v. 83 n. 2, p. e213-e221en_US
dc.identifier.issn0360-3016en_US
dc.identifier.urihttp://hdl.handle.net/10722/154726-
dc.description.abstractPurpose: To investigate the changes in salivary function and oral health-related quality of life for patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy (IMRT). Methods and Materials: A total of 57 patients with early-stage nasopharyngeal carcinoma received IMRT. The parotid and whole saliva flow was measured, and the Medical Outcomes Study 36-item short form, European Organization for Research and Treatment of Cancer Quality of Life questionnaire-C30, European Organization for Research and Treatment of Cancer Quality of Life questionnaire 35-item head-and-neck module, and Oral Health Impact Profile questionnaires were completed at baseline and 2, 6, 12, 18, and 24 months after IMRT. Results: Parotid saliva flow recovered fully after 1 year and maintained. Whole saliva flow recovered partially to 40% of baseline. A general trend of deterioration in most quality of life scales was observed after IMRT, followed by gradual recovery. Persistent oral-related symptoms were found 2 years after treatment. Conclusion: IMRT for early-stage nasopharyngeal carcinoma could only partially preserve the whole salivary function and oral health-related quality of life. © 2012 Elsevier Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ijrobpen_US
dc.relation.ispartofInternational Journal of Radiation Oncology - Biology - Physicsen_US
dc.subject.meshNasopharyngeal Neoplasms - ethnology - pathology - radiotherapy-
dc.subject.meshOral Health-
dc.subject.meshParotid Gland - physiopathology - radiation effects-
dc.subject.meshRadiotherapy, Intensity-Modulated - adverse effects - methods-
dc.subject.meshSalivation - physiology - radiation effects-
dc.titleCan intensity-modulated radiotherapy preserve oral health-related quality of life of nasopharyngeal carcinoma patients?en_US
dc.typeArticleen_US
dc.identifier.emailPow, EHN:ehnpow@hku.hken_US
dc.identifier.authorityPow, EHN=rp00030en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ijrobp.2011.12.040en_US
dc.identifier.pmid22386514-
dc.identifier.scopuseid_2-s2.0-84861101921en_US
dc.identifier.hkuros200388-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84861101921&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume83en_US
dc.identifier.issue2en_US
dc.identifier.spagee213en_US
dc.identifier.epagee221en_US
dc.identifier.eissn1879-355X-
dc.identifier.isiWOS:000303920800009-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridPow, EHN=6603825799en_US
dc.identifier.scopusauthoridKwong, DLW=54890371000en_US
dc.identifier.scopusauthoridSham, JST=24472255400en_US
dc.identifier.scopusauthoridLee, VHF=54890729100en_US
dc.identifier.scopusauthoridNg, SCY=26645099400en_US
dc.identifier.citeulike10420745-

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