File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Effect of Danshen extract on bone formation.

TitleEffect of Danshen extract on bone formation.
Authors
Issue Date2008
PublisherRoyal Australasian College of Dental Surgeons. The Journal's web site is located at http://www.racds.org
Citation
Annals Of The Royal Australasian College Of Dental Surgeons, 2008, v. 19, p. 171-174 How to Cite?
AbstractDanshen is a traditional Chinese medicine used for treatment of cardiac diseases through improving blood circulation. The authors' laboratory compared the amount of new bone formed in collagen matrix with Danshen extract with that produced by bone graft and collagen matrix alone. Eighteen bone defects, 5 mm x 10 mm were created in the parietal bone of nine New Zealand White rabbits. In the experimental group, six defects were grafted with a collagen matrix with Danshen extract. In the control groups, six defects were grafted with collagen matrix alone (active control) and six were left empty (passive control). The animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Serial sections were cut across each defect. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. A total of five times more new bone was present in defects grafted with Danshen extract in a collagen matrix than those grafted with collagen matrix alone. Very little new bone was formed in the passive control group. Danshen extract in collagen matrix has the effect of increasing new bone formation locally and can be used for bone grafting especially in cases with compromised vascular responses.
Persistent Identifierhttp://hdl.handle.net/10722/154715
ISSN
2015 SCImago Journal Rankings: 0.101

 

DC FieldValueLanguage
dc.contributor.authorWong, RWen_US
dc.contributor.authorRabie, ABen_US
dc.date.accessioned2012-08-08T08:27:04Z-
dc.date.available2012-08-08T08:27:04Z-
dc.date.issued2008en_US
dc.identifier.citationAnnals Of The Royal Australasian College Of Dental Surgeons, 2008, v. 19, p. 171-174en_US
dc.identifier.issn0158-1570en_US
dc.identifier.urihttp://hdl.handle.net/10722/154715-
dc.description.abstractDanshen is a traditional Chinese medicine used for treatment of cardiac diseases through improving blood circulation. The authors' laboratory compared the amount of new bone formed in collagen matrix with Danshen extract with that produced by bone graft and collagen matrix alone. Eighteen bone defects, 5 mm x 10 mm were created in the parietal bone of nine New Zealand White rabbits. In the experimental group, six defects were grafted with a collagen matrix with Danshen extract. In the control groups, six defects were grafted with collagen matrix alone (active control) and six were left empty (passive control). The animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Serial sections were cut across each defect. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. A total of five times more new bone was present in defects grafted with Danshen extract in a collagen matrix than those grafted with collagen matrix alone. Very little new bone was formed in the passive control group. Danshen extract in collagen matrix has the effect of increasing new bone formation locally and can be used for bone grafting especially in cases with compromised vascular responses.en_US
dc.languageengen_US
dc.publisherRoyal Australasian College of Dental Surgeons. The Journal's web site is located at http://www.racds.orgen_US
dc.relation.ispartofAnnals of the Royal Australasian College of Dental Surgeonsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBone Regeneration - Drug Effectsen_US
dc.subject.meshCollagen - Pharmacologyen_US
dc.subject.meshDrugs, Chinese Herbal - Pharmacologyen_US
dc.subject.meshParietal Bone - Surgeryen_US
dc.subject.meshPhenanthrolines - Pharmacologyen_US
dc.subject.meshRabbitsen_US
dc.subject.meshRandom Allocationen_US
dc.subject.meshWound Healing - Drug Effectsen_US
dc.titleEffect of Danshen extract on bone formation.en_US
dc.typeArticleen_US
dc.identifier.emailRabie, AB:rabie@hku.hken_US
dc.identifier.authorityRabie, AB=rp00029en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid22073474-
dc.identifier.scopuseid_2-s2.0-84859401284en_US
dc.identifier.hkuros153927-
dc.identifier.volume19en_US
dc.identifier.spage171en_US
dc.identifier.epage174en_US
dc.publisher.placeAustraliaen_US
dc.identifier.scopusauthoridWong, RW=36642905800en_US
dc.identifier.scopusauthoridRabie, AB=7007172734en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats