File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Biomimetic mineralization of dentin induced by agarose gel loaded with calcium phosphate

TitleBiomimetic mineralization of dentin induced by agarose gel loaded with calcium phosphate
Authors
Issue Date2012
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/
Citation
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2012, v. 100 B n. 1, p. 138-144 How to Cite?
AbstractA novel biomimetic mineralization system was designed to induce a layer of hydroxyapatite on a demineralized dentin surface. This system was constructed as follows. A layer of 0.5% agarose gel containing 0.26M Na(2) HPO(4) was used to cover acid-etched dentin slices, followed by a layer of agarose gel without phosphate ions. Then a neutral 0.13M CaCl(2) solution was added onto the ion-free gel surface. The mineralization system (dentin-agarose gel containing phosphate ions-CaCl(2) solution) was kept in a water bath at 37 degrees C, and the gel and CaCl(2) solution were replaced at various intervals. The results showed that the deposited hydroxyapatite crystals densely packed to each other, completely covered the dentin surface, and occluded the dentinal tubules after 10 days of biomimetic mineralization in vitro. Therefore, this method may provide the experimental basis for dentin remineralization and for a new method to treat dentin hypersensitivity and dental caries.
Persistent Identifierhttp://hdl.handle.net/10722/154691
ISSN
2015 Impact Factor: 2.881
2015 SCImago Journal Rankings: 0.784
ISI Accession Number ID
Funding AgencyGrant Number
Science and Technology Department of Jiangsu Province, ChinaBK2008362
National Natural Science Foundation of China (NSFC)30973352
81070864
NSFC/RGC81061160511
N_HKU 776/10
Funding Information:

Contract grant sponsor: Projects of Science and Technology Department of Jiangsu Province, China; contract grant number: BK2008362

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorNing, TYen_US
dc.contributor.authorXu, XHen_US
dc.contributor.authorZhu, LFen_US
dc.contributor.authorZhu, XPen_US
dc.contributor.authorChu, CHen_US
dc.contributor.authorLiu, LKen_US
dc.contributor.authorLi, QLen_US
dc.date.accessioned2012-08-08T08:26:56Z-
dc.date.available2012-08-08T08:26:56Z-
dc.date.issued2012en_US
dc.identifier.citationJournal of Biomedical Materials Research Part B: Applied Biomaterials, 2012, v. 100 B n. 1, p. 138-144en_US
dc.identifier.issn1552-4973en_US
dc.identifier.urihttp://hdl.handle.net/10722/154691-
dc.description.abstractA novel biomimetic mineralization system was designed to induce a layer of hydroxyapatite on a demineralized dentin surface. This system was constructed as follows. A layer of 0.5% agarose gel containing 0.26M Na(2) HPO(4) was used to cover acid-etched dentin slices, followed by a layer of agarose gel without phosphate ions. Then a neutral 0.13M CaCl(2) solution was added onto the ion-free gel surface. The mineralization system (dentin-agarose gel containing phosphate ions-CaCl(2) solution) was kept in a water bath at 37 degrees C, and the gel and CaCl(2) solution were replaced at various intervals. The results showed that the deposited hydroxyapatite crystals densely packed to each other, completely covered the dentin surface, and occluded the dentinal tubules after 10 days of biomimetic mineralization in vitro. Therefore, this method may provide the experimental basis for dentin remineralization and for a new method to treat dentin hypersensitivity and dental caries.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0021-9304:1/en_US
dc.relation.ispartofJournal of Biomedical Materials Research Part B: Applied Biomaterialsen_US
dc.rightsJournal of Biomedical Materials Research Part B: Applied Biomaterials. Copyright © John Wiley & Sons, Inc.-
dc.subject.meshSepharose - Chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshGels - Chemistryen_US
dc.subject.meshDurapatite - Chemical Synthesis - Chemistry - Therapeutic Useen_US
dc.subject.meshBiomimetic Materials - Chemical Synthesis - Chemistry - Therapeutic useen_US
dc.subject.meshDentin - Chemistryen_US
dc.titleBiomimetic mineralization of dentin induced by agarose gel loaded with calcium phosphateen_US
dc.typeArticleen_US
dc.identifier.emailZhu, LF: zwx33@126..comen_US
dc.identifier.emailChu, CH: chchu@hku.hk-
dc.identifier.authorityChu, CH=rp00022en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/jbm.b.31931en_US
dc.identifier.pmid21954134-
dc.identifier.scopuseid_2-s2.0-82955249220en_US
dc.identifier.hkuros205918-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-82955249220&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume100 Ben_US
dc.identifier.issue1en_US
dc.identifier.spage138en_US
dc.identifier.epage144en_US
dc.identifier.isiWOS:000297949800016-
dc.publisher.placeUnited Statesen_US
dc.relation.projectEnamel microstructure regeneration in macroscale by molecular mimetic method-
dc.identifier.scopusauthoridLi, QL=47461450000en_US
dc.identifier.scopusauthoridLiu, LK=52264021600en_US
dc.identifier.scopusauthoridChu, CH=7404345729en_US
dc.identifier.scopusauthoridZhu, XP=47461800800en_US
dc.identifier.scopusauthoridZhu, LF=54794715600en_US
dc.identifier.scopusauthoridXu, XH=54794588400en_US
dc.identifier.scopusauthoridNing, TY=54794364800en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats