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Article: Central giant cell granuloma of the jaws: Clinical and radiological evaluation of 22 cases

TitleCentral giant cell granuloma of the jaws: Clinical and radiological evaluation of 22 cases
Authors
Issue Date2009
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00256/index.htm
Citation
Skeletal Radiology, 2009, v. 38 n. 9, p. 903-909 How to Cite?
AbstractObjective: The objective was to investigate the clinical and radiological characteristics of central giant cell granulomas (CGCGs) of the jaws. Methods: A retrospective analysis of a 20-year database was performed regarding both clinical and radiological features of 22 patients affected with CGCGs of the jaws. Results: Fourteen women and 8 men were included with the age range of 7-81 years (mean 31.7 years). Among the 22 lesions, 16 were located in the mandible and 6 in the maxilla. Painless swelling was the most common clinical feature in 18 of all cases. Limited mouth opening was noted in 2 patients where the lesions involved the condyle. Radiographically, 13 lesions were homogeneously osteolytic and 9 lesions were trabeculated. Fifteen lesions were unilocular and 14 lesions presented with well-defined but not sclerotic margins. CT images in 5 patients clearly showed the trabeculation within the lesions. The follow-up ranged from 1.5 to 11 years with a mean period of 5 years. Three out of 9 aggressive and 1 out of 13 nonaggressive lesions developed recurrence. Conclusions: Diagnosis of CGCGs of the jaws depends on both correct interpretation of clinical, radiographic and pathological data. Differentiation between aggressive and nonaggressive CGCGs should be considered to improve individual treatment planning. © 2009 ISS.
Persistent Identifierhttp://hdl.handle.net/10722/154577
ISSN
2015 Impact Factor: 1.527
2015 SCImago Journal Rankings: 0.754
ISI Accession Number ID
Funding AgencyGrant Number
National Natural Science Foundation of China30600712
30872894
Funding Information:

This study was supported by grants from National Natural Science Foundation of China (30600712) to Dr. Z.-J. Sun and (30872894) to Dr. Y.-F. Zhao.

References

 

DC FieldValueLanguage
dc.contributor.authorSun, ZJen_US
dc.contributor.authorCai, Yen_US
dc.contributor.authorZwahlen, RAen_US
dc.contributor.authorZheng, YFen_US
dc.contributor.authorWang, SPen_US
dc.contributor.authorZhao, YFen_US
dc.date.accessioned2012-08-08T08:26:16Z-
dc.date.available2012-08-08T08:26:16Z-
dc.date.issued2009en_US
dc.identifier.citationSkeletal Radiology, 2009, v. 38 n. 9, p. 903-909en_US
dc.identifier.issn0364-2348en_US
dc.identifier.urihttp://hdl.handle.net/10722/154577-
dc.description.abstractObjective: The objective was to investigate the clinical and radiological characteristics of central giant cell granulomas (CGCGs) of the jaws. Methods: A retrospective analysis of a 20-year database was performed regarding both clinical and radiological features of 22 patients affected with CGCGs of the jaws. Results: Fourteen women and 8 men were included with the age range of 7-81 years (mean 31.7 years). Among the 22 lesions, 16 were located in the mandible and 6 in the maxilla. Painless swelling was the most common clinical feature in 18 of all cases. Limited mouth opening was noted in 2 patients where the lesions involved the condyle. Radiographically, 13 lesions were homogeneously osteolytic and 9 lesions were trabeculated. Fifteen lesions were unilocular and 14 lesions presented with well-defined but not sclerotic margins. CT images in 5 patients clearly showed the trabeculation within the lesions. The follow-up ranged from 1.5 to 11 years with a mean period of 5 years. Three out of 9 aggressive and 1 out of 13 nonaggressive lesions developed recurrence. Conclusions: Diagnosis of CGCGs of the jaws depends on both correct interpretation of clinical, radiographic and pathological data. Differentiation between aggressive and nonaggressive CGCGs should be considered to improve individual treatment planning. © 2009 ISS.en_US
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00256/index.htmen_US
dc.relation.ispartofSkeletal Radiologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshGranuloma, Giant Cell - Radiographyen_US
dc.subject.meshHumansen_US
dc.subject.meshJaw Neoplasms - Radiographyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshReproducibility Of Resultsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshTomography, X-Ray Computed - Methodsen_US
dc.subject.meshYoung Adulten_US
dc.titleCentral giant cell granuloma of the jaws: Clinical and radiological evaluation of 22 casesen_US
dc.typeArticleen_US
dc.identifier.emailZwahlen, RA:zwahlen@hku.hken_US
dc.identifier.authorityZwahlen, RA=rp00055en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00256-009-0740-8en_US
dc.identifier.pmid19582449-
dc.identifier.scopuseid_2-s2.0-68349098950en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68349098950&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume38en_US
dc.identifier.issue9en_US
dc.identifier.spage903en_US
dc.identifier.epage909en_US
dc.identifier.isiWOS:000268281300009-
dc.publisher.placeGermanyen_US
dc.identifier.scopusauthoridSun, ZJ=7404239630en_US
dc.identifier.scopusauthoridCai, Y=35214334700en_US
dc.identifier.scopusauthoridZwahlen, RA=7004217269en_US
dc.identifier.scopusauthoridZheng, YF=35217461900en_US
dc.identifier.scopusauthoridWang, SP=8705924300en_US
dc.identifier.scopusauthoridZhao, YF=13103599000en_US
dc.identifier.citeulike5109682-

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