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Article: Systemic effect of crude extract from rhizome of Drynaria fortunei on bone formation in mice

TitleSystemic effect of crude extract from rhizome of Drynaria fortunei on bone formation in mice
Authors
KeywordsBone formation
Drynaria fortunei
Micro-CT scan
Issue Date2006
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567
Citation
Phytotherapy Research, 2006, v. 20 n. 4, p. 313-315 How to Cite?
AbstractThe structure of the bones of mice with and without consumption of Gusuibu extracts were compared. Twenty 8-week-old male BALB/c mice were divided into two groups. In the control group ten mice were daily fed a normal diet and distilled water for drinking. In the Gusuibu group ten mice were daily fed a normal diet and distilled water mixed with Gusuibu extract for drinking. The mice were kept for 5 weeks and were then killed. Using micro-computed tomography, 20 micro-tomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. The results showed that consumption of Gusuibu extract increased the bone volume/tissue volume ratio by 6.45%. The bone trabeculae were increased by 10.00% in number so that the bone density was increased. To conclude, Gusuibu extract taken orally increased bone density. Copyright © 2006 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/154399
ISSN
2015 Impact Factor: 2.694
2015 SCImago Journal Rankings: 0.842
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, RWKen_HK
dc.contributor.authorRabie, ABMen_HK
dc.date.accessioned2012-08-08T08:25:06Z-
dc.date.available2012-08-08T08:25:06Z-
dc.date.issued2006en_HK
dc.identifier.citationPhytotherapy Research, 2006, v. 20 n. 4, p. 313-315en_HK
dc.identifier.issn0951-418Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/154399-
dc.description.abstractThe structure of the bones of mice with and without consumption of Gusuibu extracts were compared. Twenty 8-week-old male BALB/c mice were divided into two groups. In the control group ten mice were daily fed a normal diet and distilled water for drinking. In the Gusuibu group ten mice were daily fed a normal diet and distilled water mixed with Gusuibu extract for drinking. The mice were kept for 5 weeks and were then killed. Using micro-computed tomography, 20 micro-tomographic slices with an increment of 0.25 mm were acquired to cover the proximal end of the left tibia of each mouse. Quantitative morphometry of the bone structure was performed. The results showed that consumption of Gusuibu extract increased the bone volume/tissue volume ratio by 6.45%. The bone trabeculae were increased by 10.00% in number so that the bone density was increased. To conclude, Gusuibu extract taken orally increased bone density. Copyright © 2006 John Wiley & Sons, Ltd.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/12567en_HK
dc.relation.ispartofPhytotherapy Researchen_HK
dc.subjectBone formationen_HK
dc.subjectDrynaria fortuneien_HK
dc.subjectMicro-CT scanen_HK
dc.subject.meshAnimalsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred Balb Cen_US
dc.subject.meshOsteogenesis - Drug Effectsen_US
dc.subject.meshPlant Extracts - Pharmacologyen_US
dc.subject.meshPolypodiaceaeen_US
dc.subject.meshRhizomeen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.titleSystemic effect of crude extract from rhizome of Drynaria fortunei on bone formation in miceen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, RWK: fyoung@hku.hken_HK
dc.identifier.emailRabie, ABM: rabie@hku.hken_HK
dc.identifier.authorityWong, RWK=rp00038en_HK
dc.identifier.authorityRabie, ABM=rp00029en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/ptr.1842en_HK
dc.identifier.pmid16557621-
dc.identifier.scopuseid_2-s2.0-33645945867en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645945867&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume20en_HK
dc.identifier.issue4en_HK
dc.identifier.spage313en_HK
dc.identifier.epage315en_HK
dc.identifier.isiWOS:000236946700014-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridWong, RWK=7402127170en_HK
dc.identifier.scopusauthoridRabie, ABM=7007172734en_HK

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