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Article: Guided tissue regeneration/deproteinized bovine bone mineral or papilla preservation flaps alone for treatment of intrabony defects. II: Radiographic predictors and outcomes

TitleGuided tissue regeneration/deproteinized bovine bone mineral or papilla preservation flaps alone for treatment of intrabony defects. II: Radiographic predictors and outcomes
Authors
Issue Date2006
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CPE
Citation
Journal Of Clinical Periodontology, 2006, v. 33 n. 5, p. 351-358 How to Cite?
AbstractObjectives: This study reports the secondary analysis of a randomized-controlled clinical trial designed to assess the efficacy of deproteinized bovine mineral and a collagen membrane in the treatment of intrabony defects. The specific aims of this report are (1) to analyse the radiographic bone changes 1 year after therapy and (2) to assess the association between radiographic defect angle and treatment outcomes. Materials and Methods: Baseline and 12-month radiographs were collected from 120 patients with advanced chronic periodontitis from 10 centres in seven countries as part of a multi-centre clinical trial. All patients had at least one intrabony defect ≥3 mm in depth. The treatment consisted of simplified or modified papilla preservation flaps to access the defect. After debridement of the area, a deproteinized bovine mineral and a collagen membrane were applied in the test subjects, and omitted in the controls. Main outcome measures were radiographic bone fill and defect resolution 1 year after surgery. Results: One hundred and twenty pairs of radiographs were obtained, of which 110 pairs were measurable (57 tests and 53 controls). One year after treatment, radiographic resolution of the intrabony component was significantly higher in the test group (3.2±1.7 mm) when compared with the controls (1.7±1.9 mm). Multivariate analysis indicated that the treatment and the baseline radiographic depth of the intrabony defect significantly influenced the radiographic bone fill of the intrabony defect 1 year following treatment. The percentage of resolution of the defect was influenced by the treatment provided and the baseline plaque score. The baseline radiographic defect angle did not show a significant impact on the clinical and radiographic outcomes. Conclusions: Regenerative periodontal surgery with a deproteinized bovine bone mineral and a collagen membrane offered additional benefits in terms of radiographic resolution of the intrabony defect and predictability of outcomes with respect to papilla preservation flaps alone. © 2006 Blackwell Munksgaard.
Persistent Identifierhttp://hdl.handle.net/10722/154396
ISSN
2015 Impact Factor: 3.915
2015 SCImago Journal Rankings: 1.848
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLiñares, Aen_US
dc.contributor.authorCortellini, Pen_US
dc.contributor.authorLang, NPen_US
dc.contributor.authorSuvan, Jen_US
dc.contributor.authorTonetti, MSen_US
dc.date.accessioned2012-08-08T08:25:05Z-
dc.date.available2012-08-08T08:25:05Z-
dc.date.issued2006en_US
dc.identifier.citationJournal Of Clinical Periodontology, 2006, v. 33 n. 5, p. 351-358en_US
dc.identifier.issn0303-6979en_US
dc.identifier.urihttp://hdl.handle.net/10722/154396-
dc.description.abstractObjectives: This study reports the secondary analysis of a randomized-controlled clinical trial designed to assess the efficacy of deproteinized bovine mineral and a collagen membrane in the treatment of intrabony defects. The specific aims of this report are (1) to analyse the radiographic bone changes 1 year after therapy and (2) to assess the association between radiographic defect angle and treatment outcomes. Materials and Methods: Baseline and 12-month radiographs were collected from 120 patients with advanced chronic periodontitis from 10 centres in seven countries as part of a multi-centre clinical trial. All patients had at least one intrabony defect ≥3 mm in depth. The treatment consisted of simplified or modified papilla preservation flaps to access the defect. After debridement of the area, a deproteinized bovine mineral and a collagen membrane were applied in the test subjects, and omitted in the controls. Main outcome measures were radiographic bone fill and defect resolution 1 year after surgery. Results: One hundred and twenty pairs of radiographs were obtained, of which 110 pairs were measurable (57 tests and 53 controls). One year after treatment, radiographic resolution of the intrabony component was significantly higher in the test group (3.2±1.7 mm) when compared with the controls (1.7±1.9 mm). Multivariate analysis indicated that the treatment and the baseline radiographic depth of the intrabony defect significantly influenced the radiographic bone fill of the intrabony defect 1 year following treatment. The percentage of resolution of the defect was influenced by the treatment provided and the baseline plaque score. The baseline radiographic defect angle did not show a significant impact on the clinical and radiographic outcomes. Conclusions: Regenerative periodontal surgery with a deproteinized bovine bone mineral and a collagen membrane offered additional benefits in terms of radiographic resolution of the intrabony defect and predictability of outcomes with respect to papilla preservation flaps alone. © 2006 Blackwell Munksgaard.en_US
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CPEen_US
dc.relation.ispartofJournal of Clinical Periodontologyen_US
dc.subject.meshAlveolar Bone Loss - Radiography - Surgeryen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBone Matrix - Transplantationen_US
dc.subject.meshBone Regenerationen_US
dc.subject.meshBone Transplantation - Methodsen_US
dc.subject.meshCattleen_US
dc.subject.meshCollagenen_US
dc.subject.meshFemaleen_US
dc.subject.meshGingiva - Surgeryen_US
dc.subject.meshGuided Tissue Regeneration, Periodontal - Methodsen_US
dc.subject.meshHumansen_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshMaleen_US
dc.subject.meshMembranes, Artificialen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshOral Surgical Procedures - Methodsen_US
dc.subject.meshPeriodontitis - Surgeryen_US
dc.subject.meshRadiography, Dentalen_US
dc.subject.meshSurgical Flapsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleGuided tissue regeneration/deproteinized bovine bone mineral or papilla preservation flaps alone for treatment of intrabony defects. II: Radiographic predictors and outcomesen_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1600-051X.2006.00911.xen_US
dc.identifier.pmid16634957en_US
dc.identifier.scopuseid_2-s2.0-33645741207en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645741207&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume33en_US
dc.identifier.issue5en_US
dc.identifier.spage351en_US
dc.identifier.epage358en_US
dc.identifier.isiWOS:000236664100009-
dc.publisher.placeDenmarken_US
dc.identifier.scopusauthoridLiñares, A=12806692000en_US
dc.identifier.scopusauthoridCortellini, P=7004422576en_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US
dc.identifier.scopusauthoridSuvan, J=19637686000en_US
dc.identifier.scopusauthoridTonetti, MS=35602248900en_US
dc.identifier.citeulike580518-

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