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Article: In vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida species

TitleIn vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida species
Authors
Issue Date2006
PublisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1
Citation
Oral Diseases, 2006, v. 12 n. 1, p. 45-50 How to Cite?
AbstractOBJECTIVE: The combination of amine fluoride and stannous fluoride (AmF/SnF2) was, by chance, found to be antifungal in a clinical trial. This study investigated its effect on pathogenic Candida species with the hypothesis that the antifungal action on different species is variable. MATERIALS AND METHODS: Growth inhibition effect of Meridol® mouth rinse which contains 250 ppm AmF/SnF2 was evaluated on 43 reference and clinical strains of Candida albicans, C. dubliniensis, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis, and C. tropicalis. Meridol® base solution without AmF/SnF2 was used as a negative control. RESULTS: Undiluted Meridol® mouth rinse killed most study strains within a few minutes. In ascending order, C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, C. krusei and C. dubliniensis showed higher resistance against AmF/SnF2 than C. guilliermondii. CONCLUSION: AmF/SnF2 could be used as a potent adjunct to antifungal therapy for oral yeasts. Although different Candida species demonstrated variable sensitivity the most prevalent oral yeast C. albicans appeared sensitive to the AmF/SnF2 combination. © 2005 Blackwell Munksgaard All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/154390
ISSN
2015 Impact Factor: 2.0
2015 SCImago Journal Rankings: 0.828
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMeurman, JHen_US
dc.contributor.authorKari, Ken_US
dc.contributor.authorWaltimo, Ten_US
dc.contributor.authorKotiranta, Aen_US
dc.contributor.authorInkeri, Jen_US
dc.contributor.authorSamaranayake, LPen_US
dc.date.accessioned2012-08-08T08:25:03Z-
dc.date.available2012-08-08T08:25:03Z-
dc.date.issued2006en_US
dc.identifier.citationOral Diseases, 2006, v. 12 n. 1, p. 45-50en_US
dc.identifier.issn1354-523Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/154390-
dc.description.abstractOBJECTIVE: The combination of amine fluoride and stannous fluoride (AmF/SnF2) was, by chance, found to be antifungal in a clinical trial. This study investigated its effect on pathogenic Candida species with the hypothesis that the antifungal action on different species is variable. MATERIALS AND METHODS: Growth inhibition effect of Meridol® mouth rinse which contains 250 ppm AmF/SnF2 was evaluated on 43 reference and clinical strains of Candida albicans, C. dubliniensis, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis, and C. tropicalis. Meridol® base solution without AmF/SnF2 was used as a negative control. RESULTS: Undiluted Meridol® mouth rinse killed most study strains within a few minutes. In ascending order, C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, C. krusei and C. dubliniensis showed higher resistance against AmF/SnF2 than C. guilliermondii. CONCLUSION: AmF/SnF2 could be used as a potent adjunct to antifungal therapy for oral yeasts. Although different Candida species demonstrated variable sensitivity the most prevalent oral yeast C. albicans appeared sensitive to the AmF/SnF2 combination. © 2005 Blackwell Munksgaard All rights reserved.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing, Inc. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1354-523X&site=1en_US
dc.relation.ispartofOral Diseasesen_US
dc.subject.meshAmines - Pharmacologyen_US
dc.subject.meshAntifungal Agents - Pharmacologyen_US
dc.subject.meshCandida - Drug Effectsen_US
dc.subject.meshColony Count, Microbialen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshFluorides, Topical - Pharmacologyen_US
dc.subject.meshMouthwashes - Pharmacologyen_US
dc.subject.meshTin Fluorides - Pharmacologyen_US
dc.titleIn vitro antifungal effect of amine fluoride-stannous fluoride combination on oral Candida speciesen_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1601-0825.2005.01156.xen_US
dc.identifier.pmid16390468-
dc.identifier.scopuseid_2-s2.0-33645027871en_US
dc.identifier.hkuros113071-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645027871&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume12en_US
dc.identifier.issue1en_US
dc.identifier.spage45en_US
dc.identifier.epage50en_US
dc.identifier.isiWOS:000234405300006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridMeurman, JH=7006469347en_US
dc.identifier.scopusauthoridKari, K=6603526983en_US
dc.identifier.scopusauthoridWaltimo, T=7004089148en_US
dc.identifier.scopusauthoridKotiranta, A=6508273064en_US
dc.identifier.scopusauthoridInkeri, J=12785159100en_US
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US
dc.identifier.citeulike455988-

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