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Article: Experimental gingivitis in cigarette smokers: A clinical and microbiological study

TitleExperimental gingivitis in cigarette smokers: A clinical and microbiological study
Authors
Issue Date2005
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CPE
Citation
Journal Of Clinical Periodontology, 2005, v. 32 n. 5, p. 441-447 How to Cite?
AbstractObjective: To assess clinical and microbiological changes during experimental gingivitis in cigarette smokers and non-smokers. Material and Methods: Eleven current smokers (≥ 5 years) and 11 (never-) non-smokers periodontally healthy or with gingivitis (PPD ≤ 4 mm) were included. According to the original model (Löe et al. 1965), an experimental 3-week plaque accumulation period resulting in experimental gingivitis and a subsequent 2-week period of optimal plaque control were performed. Subgingival plaque samples were collected at Days 0, 21 and 35 from one site per quadrant, pooled and analysed using checkerboard DNA-DNA hybridization. Results: Smokers {mean age: 24.7 ±2.2 [standard deviation (SD)] years, range 21-28 years} had a mean lifetime cigarette exposure of 6.4 ± 2.8 (SD) pack-years, while non-smokers presented with a mean age of 23.1 ± 2.2 (SD) years (range 21-29 years). Between Days 0, 21 and 35, no statistically significant differences in mean Plaque and mean Gingival Index scores were observed between smokers and non-smokers. In both smokers and non-smokers, mean total DNA probe counts did not significantly differ nor increase between Days 0 and 21. Also, between Days 21 and 35 they did not significantly differ nor decrease. This was also true for the various proportions of bacterial complexes. Conclusion: Both current smokers and (never-) non-smokers reacted to experimental plaque accumulation with gingival inflammation. Periodontal and microbiological parameters assessed in current cigarette smokers did not significantly differ from those in non-smokers during an identical period of experimental plaque accumulation. Hence, the early host response to the bacterial challenge appears to be of similar magnitude and timing in both groups. Copyright © Blackwell Munksgaard 2005.
Persistent Identifierhttp://hdl.handle.net/10722/154319
ISSN
2015 Impact Factor: 3.915
2015 SCImago Journal Rankings: 1.848
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorSalvi, GEen_US
dc.contributor.authorRamseier, CAen_US
dc.contributor.authorKandylaki, Men_US
dc.contributor.authorSigrist, Len_US
dc.contributor.authorAwedowa, Een_US
dc.contributor.authorLang, NPen_US
dc.date.accessioned2012-08-08T08:24:35Z-
dc.date.available2012-08-08T08:24:35Z-
dc.date.issued2005en_US
dc.identifier.citationJournal Of Clinical Periodontology, 2005, v. 32 n. 5, p. 441-447en_US
dc.identifier.issn0303-6979en_US
dc.identifier.urihttp://hdl.handle.net/10722/154319-
dc.description.abstractObjective: To assess clinical and microbiological changes during experimental gingivitis in cigarette smokers and non-smokers. Material and Methods: Eleven current smokers (≥ 5 years) and 11 (never-) non-smokers periodontally healthy or with gingivitis (PPD ≤ 4 mm) were included. According to the original model (Löe et al. 1965), an experimental 3-week plaque accumulation period resulting in experimental gingivitis and a subsequent 2-week period of optimal plaque control were performed. Subgingival plaque samples were collected at Days 0, 21 and 35 from one site per quadrant, pooled and analysed using checkerboard DNA-DNA hybridization. Results: Smokers {mean age: 24.7 ±2.2 [standard deviation (SD)] years, range 21-28 years} had a mean lifetime cigarette exposure of 6.4 ± 2.8 (SD) pack-years, while non-smokers presented with a mean age of 23.1 ± 2.2 (SD) years (range 21-29 years). Between Days 0, 21 and 35, no statistically significant differences in mean Plaque and mean Gingival Index scores were observed between smokers and non-smokers. In both smokers and non-smokers, mean total DNA probe counts did not significantly differ nor increase between Days 0 and 21. Also, between Days 21 and 35 they did not significantly differ nor decrease. This was also true for the various proportions of bacterial complexes. Conclusion: Both current smokers and (never-) non-smokers reacted to experimental plaque accumulation with gingival inflammation. Periodontal and microbiological parameters assessed in current cigarette smokers did not significantly differ from those in non-smokers during an identical period of experimental plaque accumulation. Hence, the early host response to the bacterial challenge appears to be of similar magnitude and timing in both groups. Copyright © Blackwell Munksgaard 2005.en_US
dc.languageengen_US
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CPEen_US
dc.relation.ispartofJournal of Clinical Periodontologyen_US
dc.subject.meshAdulten_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshDna, Bacterial - Analysisen_US
dc.subject.meshDental Plaque - Complicationsen_US
dc.subject.meshDental Plaque Indexen_US
dc.subject.meshFemaleen_US
dc.subject.meshGingivitis - Etiology - Microbiology - Pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshNucleic Acid Hybridizationen_US
dc.subject.meshPeriodontal Indexen_US
dc.subject.meshSmoking - Adverse Effectsen_US
dc.subject.meshStatistics, Nonparametricen_US
dc.titleExperimental gingivitis in cigarette smokers: A clinical and microbiological studyen_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1600-051X.2005.00691.xen_US
dc.identifier.pmid15842257-
dc.identifier.scopuseid_2-s2.0-18244409896en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-18244409896&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume32en_US
dc.identifier.issue5en_US
dc.identifier.spage441en_US
dc.identifier.epage447en_US
dc.identifier.isiWOS:000228361000002-
dc.publisher.placeDenmarken_US
dc.identifier.scopusauthoridSalvi, GE=35600695300en_US
dc.identifier.scopusauthoridRamseier, CA=8921696800en_US
dc.identifier.scopusauthoridKandylaki, M=8262053200en_US
dc.identifier.scopusauthoridSigrist, L=8402080100en_US
dc.identifier.scopusauthoridAwedowa, E=8402080200en_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US
dc.identifier.citeulike161713-

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