Article: Ultrastructural identification of cells involved in the healing of intramembranous and endochondral bones

File Download Links for fulltext
(May Require Subscription)
Supplementary
  • Basic View
  • Metadata View
  • XML View
TitleUltrastructural identification of cells involved in the healing of intramembranous and endochondral bones
AuthorsRabie, ABM1 2
Dan, Z1
Samman, N1
KeywordsDemineralized bone matrix
Endochondral bone graft
Endochondral ossification
Intramembranous bone graft
Intramembranous ossification
Ultrastructure
Issue Date1996
PublisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom
CitationInternational Journal Of Oral And Maxillofacial Surgery, 1996, v. 25 n. 5, p. 383-388 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S0901-5027(06)80038-X
AbstractThis study was designed to identify the cells involved in the healing of autogenous intramembranous (IM) and of endochondral (EC) bone grafts. Thirty-six defects were created in the skulls of 18 adult New Zealand White rabbits. Defects were filled with IM graft alone, EC graft alone, demineralized bone matrix (DBM) alone, or combined DBM-IM and DBM-EC bone. Cellular identification was carried out at 7 and 14 days by light and electron microscopy. In IM bone, preosteoblasts, osteoblasts, and osteocytes were observed with no cartilage intermediate stage, while in EC bone, chondroblasts and chondrocytes were observed. DBM implant and DBM-IM were characterized by the presence of a cartilage stage. In conclusion, IM bone healed through an osteogenic ossification route, while EC bone healed through an EC ossification route. In the presence of demineralized EC bone matrix, IM bone adopts an EC ossification route.
ISSN0901-5027
2011 Impact Factor: 1.506
2011 SCImago Journal Rankings: 0.089
DOIhttp://dx.doi.org/10.1016/S0901-5027(06)80038-X
ISI Accession Number IDWOS:A1996VV65000015
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorRabie, ABM
dc.contributor.authorDan, Z
dc.contributor.authorSamman, N
dc.date.accessioned2012-08-08T08:22:38Z
dc.date.available2012-08-08T08:22:38Z
dc.date.issued1996
dc.description.abstractThis study was designed to identify the cells involved in the healing of autogenous intramembranous (IM) and of endochondral (EC) bone grafts. Thirty-six defects were created in the skulls of 18 adult New Zealand White rabbits. Defects were filled with IM graft alone, EC graft alone, demineralized bone matrix (DBM) alone, or combined DBM-IM and DBM-EC bone. Cellular identification was carried out at 7 and 14 days by light and electron microscopy. In IM bone, preosteoblasts, osteoblasts, and osteocytes were observed with no cartilage intermediate stage, while in EC bone, chondroblasts and chondrocytes were observed. DBM implant and DBM-IM were characterized by the presence of a cartilage stage. In conclusion, IM bone healed through an osteogenic ossification route, while EC bone healed through an EC ossification route. In the presence of demineralized EC bone matrix, IM bone adopts an EC ossification route.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationInternational Journal Of Oral And Maxillofacial Surgery, 1996, v. 25 n. 5, p. 383-388 [How to Cite?]
DOI: http://dx.doi.org/10.1016/S0901-5027(06)80038-X
dc.identifier.doihttp://dx.doi.org/10.1016/S0901-5027(06)80038-X
dc.identifier.epage388
dc.identifier.hkuros21692
dc.identifier.isiWOS:A1996VV65000015
dc.identifier.issn0901-5027
2011 Impact Factor: 1.506
2011 SCImago Journal Rankings: 0.089
dc.identifier.issue5
dc.identifier.pmid8961024
dc.identifier.scopuseid_2-s2.0-0030255304
dc.identifier.spage383
dc.identifier.urihttp://hdl.handle.net/10722/153981
dc.identifier.volume25
dc.languageeng
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/ijom
dc.publisher.placeUnited Kingdom
dc.relation.ispartofInternational Journal of Oral and Maxillofacial Surgery
dc.relation.referencesReferences in Scopus
dc.subject.meshAnimals
dc.subject.meshBone Matrix - Transplantation - Ultrastructure
dc.subject.meshBone Regeneration - Physiology
dc.subject.meshBone Transplantation - Methods - Pathology
dc.subject.meshCartilage - Cytology - Ultrastructure
dc.subject.meshDecalcification Technique
dc.subject.meshMicroscopy, Electron
dc.subject.meshOsteoblasts - Ultrastructure
dc.subject.meshOsteocytes - Ultrastructure
dc.subject.meshOsteogenesis - Physiology
dc.subject.meshRabbits
dc.subject.meshSkull - Surgery - Ultrastructure
dc.subject.meshTransplantation, Autologous
dc.subject.meshWound Healing - Physiology
dc.subjectDemineralized bone matrix
dc.subjectEndochondral bone graft
dc.subjectEndochondral ossification
dc.subjectIntramembranous bone graft
dc.subjectIntramembranous ossification
dc.subjectUltrastructure
dc.titleUltrastructural identification of cells involved in the healing of intramembranous and endochondral bones
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Prince Philip Dental Hospital