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Article: Antimicrobial treatment of peri-implant infections.

TitleAntimicrobial treatment of peri-implant infections.
Authors
Issue Date1992
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLR
Citation
Clinical Oral Implants Research, 1992, v. 3 n. 4, p. 162-168 How to Cite?
AbstractThe purpose of this study was to investigate the possibility of antimicrobial treatment of peri-implant infections associated with a periodontitis-like subgingival microbiota. Nine partially or fully edentulous patients with titanium hollow cylinder implants were selected which showed loss of bone and probing depths > or = 5 mm on one or several implants after at least 6 months following installation. They also yielded subgingival microbial samples with > or = 10(6) CFU/ml, including > or = 20% gram-negative anaerobic bacteria. The treatment included mechanical cleaning, irrigation of all peri-implant pockets > 3 mm with 0.5% chlorhexidine and systemic antimicrobial therapy (1000 mg ornidazole for 10 consecutive days). After therapy, bleeding scores decreased immediately and, over a one-year observation period, remained significantly lower than before treatment. A significant gradual reduction in mean probing depths was detected over this one-year period; only one case showed no improvement of local probing depth. Microbiological parameters indicated an instantaneous quantitative and qualitative change following treatment. Subsequently, several of these parameters tended to shift back towards pretreatment values. In the second half of the observation period, however, this tendency was reversed, and levels significantly different from baseline were eventually established. This study demonstrated that treatment aiming at reducing the subgingival bacterial mass and suppressing the anaerobic segment had a beneficial effect in patients suffering from peri-implantitis.
Persistent Identifierhttp://hdl.handle.net/10722/153810
ISSN
2015 Impact Factor: 3.464
2015 SCImago Journal Rankings: 1.427

 

DC FieldValueLanguage
dc.contributor.authorMombelli, Aen_US
dc.contributor.authorLang, NPen_US
dc.date.accessioned2012-08-08T08:21:42Z-
dc.date.available2012-08-08T08:21:42Z-
dc.date.issued1992en_US
dc.identifier.citationClinical Oral Implants Research, 1992, v. 3 n. 4, p. 162-168en_US
dc.identifier.issn0905-7161en_US
dc.identifier.urihttp://hdl.handle.net/10722/153810-
dc.description.abstractThe purpose of this study was to investigate the possibility of antimicrobial treatment of peri-implant infections associated with a periodontitis-like subgingival microbiota. Nine partially or fully edentulous patients with titanium hollow cylinder implants were selected which showed loss of bone and probing depths > or = 5 mm on one or several implants after at least 6 months following installation. They also yielded subgingival microbial samples with > or = 10(6) CFU/ml, including > or = 20% gram-negative anaerobic bacteria. The treatment included mechanical cleaning, irrigation of all peri-implant pockets > 3 mm with 0.5% chlorhexidine and systemic antimicrobial therapy (1000 mg ornidazole for 10 consecutive days). After therapy, bleeding scores decreased immediately and, over a one-year observation period, remained significantly lower than before treatment. A significant gradual reduction in mean probing depths was detected over this one-year period; only one case showed no improvement of local probing depth. Microbiological parameters indicated an instantaneous quantitative and qualitative change following treatment. Subsequently, several of these parameters tended to shift back towards pretreatment values. In the second half of the observation period, however, this tendency was reversed, and levels significantly different from baseline were eventually established. This study demonstrated that treatment aiming at reducing the subgingival bacterial mass and suppressing the anaerobic segment had a beneficial effect in patients suffering from peri-implantitis.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLRen_US
dc.relation.ispartofClinical oral implants researchen_US
dc.subject.meshBacteria, Anaerobic - Isolation & Purificationen_US
dc.subject.meshBacterial Infections - Drug Therapy - Etiologyen_US
dc.subject.meshChlorhexidine - Therapeutic Useen_US
dc.subject.meshColony Count, Microbialen_US
dc.subject.meshDental Implants - Adverse Effectsen_US
dc.subject.meshDental Plaque Indexen_US
dc.subject.meshHumansen_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshOrnidazole - Therapeutic Useen_US
dc.subject.meshPeriodontal Indexen_US
dc.subject.meshPeriodontitis - Drug Therapy - Microbiologyen_US
dc.subject.meshProsthesis Failureen_US
dc.subject.meshProsthesis-Related Infections - Drug Therapy - Etiologyen_US
dc.subject.meshRegression Analysisen_US
dc.titleAntimicrobial treatment of peri-implant infections.en_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1298430en_US
dc.identifier.scopuseid_2-s2.0-0027032001en_US
dc.identifier.volume3en_US
dc.identifier.issue4en_US
dc.identifier.spage162en_US
dc.identifier.epage168en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridMombelli, A=7006180872en_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US

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