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Article: The effect of chlorhexidine and benzydamine mouthwashes on mucositis induced by therapeutic irradiation

TitleThe effect of chlorhexidine and benzydamine mouthwashes on mucositis induced by therapeutic irradiation
Authors
Issue Date1988
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/crad
Citation
Clinical Radiology, 1988, v. 39 n. 3, p. 291-294 How to Cite?
AbstractA variety of mouthwashes are frequently used in the management of irradiation-induced mucositis. Benzydamine has recently been introduced for alleviating this condition. Its efficacy as a mouthwash was compared with chlorhexidine in two groups of patients receiving radiotherapy for oral carcinoma. Mucositis and pain were recorded over a 6 week period and oral carriage of Candida species, coliforms and Staphylococcus aureus was assessed using an oral rinse technique. There was no significant difference in the mucositis scores, overall pain scores or the yeast and bacterial species isolated between the two treatment groups. However, 58% (7 out of 12) and 92% (12 out of 13) patients reported oral discomfort when rinsing the mouth with chlorhexidine and benzydamine, respectively. In both groups, the most common coliform isolated was Klebsiella pneumoniae and the carriage of yeasts was significantly greater than that of coliforms. These results indicate that, although the individual patient acceptance of chlorhexidine is better than benzydamine, there is little difference between the two mouthwashes both in controlling pain and mucositis or in the oral carriage of the micro-organisms studied.
Persistent Identifierhttp://hdl.handle.net/10722/153645
ISSN
2015 Impact Factor: 2.151
2015 SCImago Journal Rankings: 0.864
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSamaranayake, LPen_US
dc.contributor.authorRobertson, AGen_US
dc.contributor.authorMacfarlane, TWen_US
dc.contributor.authorHunter, IPen_US
dc.contributor.authorMacfarlane, Gen_US
dc.contributor.authorSoutar, DSen_US
dc.contributor.authorFerguson, MMen_US
dc.date.accessioned2012-08-08T08:20:49Z-
dc.date.available2012-08-08T08:20:49Z-
dc.date.issued1988en_US
dc.identifier.citationClinical Radiology, 1988, v. 39 n. 3, p. 291-294en_US
dc.identifier.issn0009-9260en_US
dc.identifier.urihttp://hdl.handle.net/10722/153645-
dc.description.abstractA variety of mouthwashes are frequently used in the management of irradiation-induced mucositis. Benzydamine has recently been introduced for alleviating this condition. Its efficacy as a mouthwash was compared with chlorhexidine in two groups of patients receiving radiotherapy for oral carcinoma. Mucositis and pain were recorded over a 6 week period and oral carriage of Candida species, coliforms and Staphylococcus aureus was assessed using an oral rinse technique. There was no significant difference in the mucositis scores, overall pain scores or the yeast and bacterial species isolated between the two treatment groups. However, 58% (7 out of 12) and 92% (12 out of 13) patients reported oral discomfort when rinsing the mouth with chlorhexidine and benzydamine, respectively. In both groups, the most common coliform isolated was Klebsiella pneumoniae and the carriage of yeasts was significantly greater than that of coliforms. These results indicate that, although the individual patient acceptance of chlorhexidine is better than benzydamine, there is little difference between the two mouthwashes both in controlling pain and mucositis or in the oral carriage of the micro-organisms studied.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/craden_US
dc.relation.ispartofClinical Radiologyen_US
dc.subject.meshAgeden_US
dc.subject.meshBenzydamine - Therapeutic Useen_US
dc.subject.meshCandida - Isolation & Purificationen_US
dc.subject.meshCarcinoma, Squamous Cell - Radiotherapyen_US
dc.subject.meshChlorhexidine - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshKlebsiella Pneumoniae - Isolation & Purificationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMouth Mucosaen_US
dc.subject.meshMouth Neoplasms - Radiotherapyen_US
dc.subject.meshMouthwashes - Therapeutic Useen_US
dc.subject.meshPyrazoles - Therapeutic Useen_US
dc.subject.meshRadiotherapy - Adverse Effectsen_US
dc.subject.meshStomatitis - Etiology - Microbiology - Therapyen_US
dc.titleThe effect of chlorhexidine and benzydamine mouthwashes on mucositis induced by therapeutic irradiationen_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid3293887-
dc.identifier.scopuseid_2-s2.0-0023940578en_US
dc.identifier.volume39en_US
dc.identifier.issue3en_US
dc.identifier.spage291en_US
dc.identifier.epage294en_US
dc.identifier.isiWOS:A1988N567500018-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US
dc.identifier.scopusauthoridRobertson, AG=35553857700en_US
dc.identifier.scopusauthoridMacFarlane, TW=7005128465en_US
dc.identifier.scopusauthoridHunter, IP=7101836923en_US
dc.identifier.scopusauthoridMacFarlane, G=36729843300en_US
dc.identifier.scopusauthoridSoutar, DS=7004787094en_US
dc.identifier.scopusauthoridFerguson, MM=7402593127en_US

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