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Article: Estimating reproduction numbers for adults and children from case data

TitleEstimating reproduction numbers for adults and children from case data
Authors
Issue Date2011
PublisherThe Royal Society. The Journal's web site is located at http://publishing.royalsociety.org/index.cfm?page=1572
Citation
Journal Of The Royal Society Interface, 2011, v. 8 n. 62, p. 1248-1259 How to Cite?
AbstractWe present a method for estimating reproduction numbers for adults and children from daily onset data, using pandemic influenza A(H1N1) data as a case study. We investigate the impact of different underlying transmission assumptions on our estimates, and identify that asymmetric reproduction matrices are often appropriate. Under-reporting of cases can bias estimates of the reproduction numbers if reporting rates are not equal across the two age groups. However, we demonstrate that the estimate of the higher reproduction number is robust to disproportionate data-thinning. Applying the method to 2009 pandemic influenza H1N1 data from Japan, we demonstrate that the reproduction number for children was considerably higher than that of adults, and that our estimates are insensitive to our choice of reproduction matrix. © 2011 The Royal Society.
Persistent Identifierhttp://hdl.handle.net/10722/151749
ISSN
2015 Impact Factor: 3.818
2015 SCImago Journal Rankings: 1.622
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGlass, Ken_US
dc.contributor.authorMercer, GNen_US
dc.contributor.authorNishiura, Hen_US
dc.contributor.authorMcbryde, ESen_US
dc.contributor.authorBecker, NGen_US
dc.date.accessioned2012-06-26T06:27:49Z-
dc.date.available2012-06-26T06:27:49Z-
dc.date.issued2011en_US
dc.identifier.citationJournal Of The Royal Society Interface, 2011, v. 8 n. 62, p. 1248-1259en_US
dc.identifier.issn1742-5689en_US
dc.identifier.urihttp://hdl.handle.net/10722/151749-
dc.description.abstractWe present a method for estimating reproduction numbers for adults and children from daily onset data, using pandemic influenza A(H1N1) data as a case study. We investigate the impact of different underlying transmission assumptions on our estimates, and identify that asymmetric reproduction matrices are often appropriate. Under-reporting of cases can bias estimates of the reproduction numbers if reporting rates are not equal across the two age groups. However, we demonstrate that the estimate of the higher reproduction number is robust to disproportionate data-thinning. Applying the method to 2009 pandemic influenza H1N1 data from Japan, we demonstrate that the reproduction number for children was considerably higher than that of adults, and that our estimates are insensitive to our choice of reproduction matrix. © 2011 The Royal Society.en_US
dc.languageengen_US
dc.publisherThe Royal Society. The Journal's web site is located at http://publishing.royalsociety.org/index.cfm?page=1572en_US
dc.relation.ispartofJournal of the Royal Society Interfaceen_US
dc.subject.meshAdulten_US
dc.subject.meshBasic Reproduction Numberen_US
dc.subject.meshChilden_US
dc.subject.meshData Interpretation, Statisticalen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshHumansen_US
dc.subject.meshInfluenza A Virus, H1n1 Subtype - Growth & Developmenten_US
dc.subject.meshInfluenza, Human - Epidemiology - Transmissionen_US
dc.subject.meshJapan - Epidemiologyen_US
dc.titleEstimating reproduction numbers for adults and children from case dataen_US
dc.typeArticleen_US
dc.identifier.emailNishiura, H:nishiura@hku.hken_US
dc.identifier.authorityNishiura, H=rp01488en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1098/rsif.2010.0679en_US
dc.identifier.pmid21345858-
dc.identifier.scopuseid_2-s2.0-79961110734en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79961110734&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume8en_US
dc.identifier.issue62en_US
dc.identifier.spage1248en_US
dc.identifier.epage1259en_US
dc.identifier.isiWOS:000293069800003-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridGlass, K=7006027026en_US
dc.identifier.scopusauthoridMercer, GN=36440043700en_US
dc.identifier.scopusauthoridNishiura, H=7005501836en_US
dc.identifier.scopusauthoridMcBryde, ES=24080701400en_US
dc.identifier.scopusauthoridBecker, NG=15024329600en_US
dc.identifier.citeulike9661361-

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